Gene News and Research

Latest Gene News and Research

New DisCo method allows scRNA-seq to efficiently process samples with fewer cells

Single-cell RNA sequencing, or "scRNA-seq" for short, is a technique that allows scientists to study the expression of genes in an individual cell within a mixed population – which is virtually how all cells exist in the body's tissues.

15 Feb 2022

SARS-CoV-2 ORF6 inhibits mRNA export to favour viral translation and suppress innate signalling

A recent study posted to the bioRxiv* pre-print server investigated the ability of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to inhibit the human immune response against viral infection.

15 Feb 2022

Cardiovascular markers for predicting clinical outcomes in SARS-CoV-2 infection

In a recent study posted to the medRxiv* preprint server, an interdisciplinary team of researchers from Toronto, Canada, characterized the markers of endothelial function and developed micro ribonucleic acid (miRNA) expression atlas in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-positive and -negative patients admitted to the intensive care unit (ICU).

15 Feb 2022

UCI biologists discover how a protective mutation may reduce Alzheimer's risk

While the word "mutation" may conjure up alarming notions, a mutation in brain immune cells serves a positive role in protecting people against Alzheimer's disease.

14 Feb 2022

Surprising discovery about genetic form of microcephaly has potential to inform treatment strategies

Virginia Tech researchers publishing in the Journal of Medical Genetics made a discovery about a genetic form of microcephaly -- a condition where babies' heads and brains are smaller and grow more slowly than those of unaffected children.

14 Feb 2022

Hundreds of new proteins that could play a role in cystic fibrosis discovered

Researchers at the University of Toronto have identified hundreds of new proteins that could play a role in cystic fibrosis, and which may shed light on why some patients respond better than others to current therapies.

14 Feb 2022

Physicists investigate the usefulness of gene expression tests for cancer therapy

Following surgery, patients with breast cancer are faced with the question of whether additional chemotherapy is necessary and really effective.

14 Feb 2022

New research could deliver a breakthrough for kids suffering from severe form of genetic epilepsy

New research from the University of South Australia could deliver a breakthrough for children suffering one of the most severe forms of genetic epilepsy, reducing the frequency of their seizures and improving their quality of life.

14 Feb 2022

Testes found to be a viral reservoir for SARS-CoV-2 replication

In a recent study posted to the medRxiv* pre-print server, researchers used a suite of methods to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the testis of patients who died from coronavirus disease 2019 (COVID-19) to gain insights into SARS-CoV-2 tropism inside testis and its impact on male fertility.

13 Feb 2022

Study provides evidence for spike protein-independent attenuation of SARS-CoV-2 Omicron variant

A new study provided the structural basis for a robust interaction between the receptor-binding domain of the SARS-CoV-2 Omicron spike protein and mouse ACE2.

13 Feb 2022

Spatial transcriptomics-driven gene mapping offers new insights into inflammatory bowel disease

Using a technique called spatial transcriptomics, researchers at Karolinska Institutet in Sweden have analyzed the gene expression in the mouse colon and created a map showing where in the tissue individual genes are expressed.

12 Feb 2022

Researchers discover how ovarian cancer hides from the body's immune system

Researchers at the University of Helsinki discovered how ovarian cancer hides from the body's immune system. The findings will help develop novel precision therapies for ovarian cancer, a common and aggressive cancer type.

12 Feb 2022

First unbiased proteome scale study expands the number of known transcriptional activators

Also known as transcriptional activators for their ability to induce transcription of genes into RNA messages, these proteins are essential for the cells to function properly. Yet little is known about these proteins, and it wasn't clear how many activators there might be in human cells – until now.

11 Feb 2022

Yale researchers confirm the health benefits of moderate calorie restrictions in humans

Decades of research has shown that limits on calorie intake by flies, worms, and mice can enhance life span in laboratory conditions. But whether such calorie restriction can do the same for humans remains unclear.

11 Feb 2022

Deactivation of PLa2g7 gene mimics anti-aging effects of caloric restriction in mice

Deactivation of the gene PLa2g7 partially mimics the anti-aging effects of caloric restriction (CR) in mice, researchers report.

11 Feb 2022

Molecular treatment works against metastatic cancer that spread to the brain

Mount Sinai researchers conducting clinical trials of a drug targeting a cancer gene found that it increased metastatic cancer patients' survival and was able to work within the brain, according to a study published in Clinical Cancer Research in February.

10 Feb 2022

Gene News and Research

Latest Gene News and Research

New DisCo method allows scRNA-seq to efficiently process samples with fewer cells

SARS-CoV-2 ORF6 inhibits mRNA export to favour viral translation and suppress innate signalling

Cardiovascular markers for predicting clinical outcomes in SARS-CoV-2 infection

UCI biologists discover how a protective mutation may reduce Alzheimer's risk

Surprising discovery about genetic form of microcephaly has potential to inform treatment strategies

Hundreds of new proteins that could play a role in cystic fibrosis discovered

Physicists investigate the usefulness of gene expression tests for cancer therapy

New research could deliver a breakthrough for kids suffering from severe form of genetic epilepsy

Testes found to be a viral reservoir for SARS-CoV-2 replication

Study provides evidence for spike protein-independent attenuation of SARS-CoV-2 Omicron variant

Spatial transcriptomics-driven gene mapping offers new insights into inflammatory bowel disease

Researchers discover how ovarian cancer hides from the body's immune system

First unbiased proteome scale study expands the number of known transcriptional activators

Yale researchers confirm the health benefits of moderate calorie restrictions in humans

Deactivation of PLa2g7 gene mimics anti-aging effects of caloric restriction in mice

Molecular treatment works against metastatic cancer that spread to the brain

Drugs used to increase insulin signaling may be effective therapeutic strategy for autism

Scientists introduce a genetic mutation to provide protection against Alzheimer's disease

Gene variants associated with acute kidney injury in Black veterans hospitalized with COVID-19

Epigenetic effects of pollutants may persist long enough to influence the evolutionary process

eBook: Using iPSCs models for human disease research and drug discovery eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research