Gene News and Research

Latest Gene News and Research

Foundational characterization of a new bat-borne ebolavirus and its potential as a human pathogen

Researchers sought to evaluate the zoonotic potential of BOMV to assess the level of risk to public health.

24 Feb 2022

Immunomolecular detection method to rapidly and accurately detect complete SARS-CoV-2 virions

Researchers developed a hybrid assay incorporating immunological antibody-based viral spike protein capture with molecular nucleic acid amplification by qRT-PCR.

24 Feb 2022

Omicron BA. 2 reinfections can occur shortly following BA.1 infection

Researchers investigated the probability of Omicron BA.2 reinfections following SARS-CoV-2 Omicron BA.1 initial infection by whole genomic sequencing in the period of dominance of these subvariants in Denmark.

24 Feb 2022

Study shows SARS-CoV-2 hijacks mitochondrial transcriptional machinery resulting in organ failure and death

In a new study, researchers studied SARS-CoV-2 infection on the transcription of mitochondrial oxidative phosphorylation, glycolysis, nutrient sensing, and stress response genes.

24 Feb 2022

Research reveals why a common genetic variant worsens outcomes for people with ALS and FTD

A pioneering new study led by UCL and National Institutes of Health (NIH) scientists has revealed, for the first time, why a common genetic variant worsens disease outcomes for people with the devastating adult-onset neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).

24 Feb 2022

Scientists discover how a rare genetic disorder disrupts key neural interactions in the developing brain

Every time you chew, talk, yawn, or sense the zap of a toothache, cranial nerve cells are shuttling electrochemical signals to your brain.

23 Feb 2022

Tiny lipid-based nanoparticles carry genetic instructions directly into the lungs

Researchers at the Tufts University School of Engineering are building a reputation for precision targeting in drug delivery.

23 Feb 2022

Neanderthal gene makes people susceptible to COVID-19, but protects against HIV

A study recently published in the top-tier journal Proceedings of the National Academy of Sciences of the United States of America (PNAS) shows how a specific gene flow from Neandertals can act as a double-edged sword by increasing the risk for the development of severe coronavirus disease 2019 (COVID-19), and at the same time decreasing the risk for the infection with the human immunodeficiency virus (HIV).

23 Feb 2022

Genetic mutation associated with perceived inadequate milk supply in mothers

Leading health care organizations recommend exclusive breastfeeding for six months after birth, yet some mothers report stopping due to a perceived lack of milk supply.

23 Feb 2022

Study suggests a broader approach to decrease the transmission of pathogens

Scientists have extensively studied water and sanitation interventions to decrease the transmission of pathogens and disease prevention.

23 Feb 2022

Genetics may influence how the body responds to vaccines and boosters

Genetics play an important role in how our bodies respond to vaccines and booster shots, suggesting that certain protective responses elicited by vaccination could be more effective with personalization, according to a new study led by University of Michigan researchers.

23 Feb 2022

Study demonstrates that TMPRSS2, which is key to SARS-CoV-2 cell entry, is a tumor suppressor

The role played by the host enzyme TMPRSS2 in infection and cancer is the focus of a new study.

23 Feb 2022

Study proposes SARS-CoV-2-encoded peptide presented by HLA-E may suppress inhibition of natural killer cells

A recent study reported the abrogation of inhibition of the NK cells by a SARS-CoV-2-encoded protein presented by HLA-E.

23 Feb 2022

Why is it Important to Democratize Proteomics Data?

In this interview, we speak to Steve Kosteski from IsoPlexis about the importance of single-cell proteomics within the life sciences sector.

From Society for Laboratory Automation and Screening (SLAS) 23 Feb 2022

hAELVi cell infection model mimics SARS-CoV-2 Omicron infection in lower respiratory tract of humans

In a recent study posted to the Research Square* preprint server, which is under consideration at Scientific Reports, a team of researchers developed a novel human Alveolar Epithelial Lentivirus immortalized (hAELVi) cell infection model to estimate the replication potential of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other respiratory viruses in the lower respiratory tract of humans.

23 Feb 2022

Gene therapy leads to durable transfusion independence in youngest patients with thalassemia

Over 90 percent of patients with transfusion-dependent thalassemia, an inherited blood disorder, no longer needed monthly blood transfusions years after receiving gene therapy, according to an international Phase 3 clinical trial that for the first time included children younger than 12 years of age.

22 Feb 2022

Gene News and Research

Latest Gene News and Research

Foundational characterization of a new bat-borne ebolavirus and its potential as a human pathogen

Immunomolecular detection method to rapidly and accurately detect complete SARS-CoV-2 virions

Omicron BA. 2 reinfections can occur shortly following BA.1 infection

Study shows SARS-CoV-2 hijacks mitochondrial transcriptional machinery resulting in organ failure and death

Research reveals why a common genetic variant worsens outcomes for people with ALS and FTD

Scientists discover how a rare genetic disorder disrupts key neural interactions in the developing brain

Tiny lipid-based nanoparticles carry genetic instructions directly into the lungs

Neanderthal gene makes people susceptible to COVID-19, but protects against HIV

Genetic mutation associated with perceived inadequate milk supply in mothers

Study suggests a broader approach to decrease the transmission of pathogens

Genetics may influence how the body responds to vaccines and boosters

Study demonstrates that TMPRSS2, which is key to SARS-CoV-2 cell entry, is a tumor suppressor

Study proposes SARS-CoV-2-encoded peptide presented by HLA-E may suppress inhibition of natural killer cells

Why is it Important to Democratize Proteomics Data?

hAELVi cell infection model mimics SARS-CoV-2 Omicron infection in lower respiratory tract of humans

Gene therapy leads to durable transfusion independence in youngest patients with thalassemia

CD91 receptor promotes SARS-CoV-2 infection

Novel platform can become a potential approach for personalized cancer treatments

Study explores the decline in viral load and immune response in COVID-19 patients

Severity of SARS-CoV-2 infections with Omicron BA.2 variant relative to the BA.1 variant in South Africa

eBook: Using iPSCs models for human disease research and drug discovery eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research