Gene News and Research

Latest Gene News and Research

Study explains how the B.1.1.7 SARS-CoV-2 variant is more transmissible

New research led by Thushan I. de Silva from the University of Sheffield proposes that increases in subgenomic RNA (sgRNA) expression cause increased viral transmissibility and subsequent infection. They suggest the ORF9 protein, found in high amounts of sgRNA, could be regulating interferon responses.

4 Mar 2021

New mRNA treatment appears to stop replication of flu and Covid-19 viruses

With a relatively minor genetic change, a new treatment developed by researchers at the Georgia Institute of Technology and Emory University appears to stop replication of both flu viruses and the virus that causes Covid-19.

4 Mar 2021

Menopausal changes may drive a heightened appetite for fatty foods and weight gain

A new study in mice suggests that declining estrogen levels lower the taste buds' sensitivity to fats, which may drive a heightened appetite for fatty foods - and weight gain - after menopause.

4 Mar 2021

Study reports persistent SARS-CoV-2 with increasing viral variants in pediatric patients

New research, published on medRxiv preprint server, has reported the effect of prolonged SARS-CoV-2 infection in immunocompromised children and young adults.

4 Mar 2021

Genetic variation associated with COVID-19 outcome

Host genetics play a role in disease progression and prognosis. A paper recently uploaded to the preprint server medRxiv by Dubé et al. (1st March 2021) identifies several alleles associated with the gene natriuretic peptide receptor C (NPR3) that may impact disease severity.

3 Mar 2021

People diagnosed with alpha-1 antitrypsin deficiency more likely to stop smoking, study shows

New research shows that people diagnosed with a genetic condition, called alpha-1 antitrypsin deficiency (AATD), are far more likely to stop smoking and therefore prevent the development of lung disease.

3 Mar 2021

Report: Probabilistic forecasts of the impact of vaccines and variants on the U.S. COVID trajectory

In a report summary released today Thomas McAndrew, a computational scientist and assistant professor at Lehigh University's College of Health includes probabilistic forecasts of the impact of vaccines and variants on the U.S. COVID trajectory over the next few weeks.

3 Mar 2021

PICI awards $3 million to support early career cancer researchers

From improving immunotherapy response in childhood cancer patients, to better understanding how cancer's spread to the liver affects the body's immune system, to helping T cells stay energized to fight cancer, The Parker Institute for Cancer Immunotherapy (PICI)'s 2021 class of early career researchers award recipients are pursuing ideas that have the potential to change the face of oncology.

3 Mar 2021

New transcriptome‐based aging clock reads the biological age of an organism

Using the model organism Caenorhabditis elegans, researchers at the University of Cologne have developed an 'aging clock' that reads the biological age of an organism directly from its gene expression, the transcriptome.

3 Mar 2021

UK public health authorities review early data on the effectiveness of Pfizer and AstraZeneca COVID-19 vaccines

A team of UK scientists has recently evaluated the effectiveness of the Pfizer (BNT162b2) and AstraZeneca (ChAdOx1) vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The findings reveal that both vaccines are effective in significantly reducing SARS-CoV-2 infection in older adults and providing long-term protection.

3 Mar 2021

Combination of therapies may benefit patients with mitochondrial respiratory chain disorders

Researchers from the Mitochondrial Medicine Frontier Program at Children's Hospital of Philadelphia (CHOP) have demonstrated how one combination of therapies may be beneficial for patients with mitochondrial respiratory chain disorders.

3 Mar 2021

How SARS-CoV-2 proteins affect vascular functionality

The study, published on the pre-print server medRxiv, can pinpoint and isolate how each of the SARS-CoV-2 proteins independently affects the endothelial response and directly gauge endothelial functionality.

3 Mar 2021

Quantifying SARS-CoV-2 viral load in hospitalized patients

A new paper, published on the medRxiv preprint server, investigates the role of subgenomic RNA transcripts in SARS-CoV-2 infection. Earlier, scientists believed that subgenomic RNA could be traceable infective markers to monitor infectivity.

2 Mar 2021

Disruption of lung biological clock may explain flu risk in adults who survived premature birth

Disruptions in the circadian rhythms in lung cells may explain why adults who survived premature birth are often more at risk of severe influenza infections, suggests a study in mice published today in eLife.

2 Mar 2021

Yale researchers identify multiple genes involved in suppression of axon regeneration

When central nervous system cells in the brain and spine are damaged by disease or injury, they fail to regenerate, limiting the body's ability to recover.

2 Mar 2021

Sequential administration of immunotherapy and targeted therapy prolongs anti-tumor responses

Advanced melanoma is one of the deadliest types of cancer, with a 5-year survival rate of only 27% for patients with distant metastases.

2 Mar 2021

Researchers develop a genetic patch to prevent hereditary deafness

They can hear well up to about forty years old, but then suddenly deafness strikes people with DFNA9. The cells of the inner ear can no longer reverse the damage caused by a genetic defect in their DNA.

2 Mar 2021

Scientists reprogram a common bacterium to make designer sugar-based drug

Envisioning an animal-free drug supply, scientists have - for the first time - reprogrammed a common bacterium to make a designer polysaccharide molecule used in pharmaceuticals and nutraceuticals.

2 Mar 2021

Evonik partners with BioNTech to manufacture lipids for COVID-19 vaccine

Caused by SARS-CoV-2, the coronavirus disease 2019 (COVID-19) pandemic continues to spread across the globe.

From Evonik 2 Mar 2021

Optimal storage protocols of wastewater samples for SARS-CoV-2 RNA detection

A new preprint released on the medRxiv* server by researchers at the University of Innsbruck, Austria, takes this further in order to establish the limits of storage procedures while working on viral surveillance in this area.

2 Mar 2021

Gene News and Research

Latest Gene News and Research

Study explains how the B.1.1.7 SARS-CoV-2 variant is more transmissible

New mRNA treatment appears to stop replication of flu and Covid-19 viruses

Menopausal changes may drive a heightened appetite for fatty foods and weight gain

Study reports persistent SARS-CoV-2 with increasing viral variants in pediatric patients

Genetic variation associated with COVID-19 outcome

People diagnosed with alpha-1 antitrypsin deficiency more likely to stop smoking, study shows

Report: Probabilistic forecasts of the impact of vaccines and variants on the U.S. COVID trajectory

PICI awards $3 million to support early career cancer researchers

New transcriptome‐based aging clock reads the biological age of an organism

UK public health authorities review early data on the effectiveness of Pfizer and AstraZeneca COVID-19 vaccines

Combination of therapies may benefit patients with mitochondrial respiratory chain disorders

How SARS-CoV-2 proteins affect vascular functionality

Quantifying SARS-CoV-2 viral load in hospitalized patients

Disruption of lung biological clock may explain flu risk in adults who survived premature birth

Yale researchers identify multiple genes involved in suppression of axon regeneration

Sequential administration of immunotherapy and targeted therapy prolongs anti-tumor responses

Researchers develop a genetic patch to prevent hereditary deafness

Scientists reprogram a common bacterium to make designer sugar-based drug

Evonik partners with BioNTech to manufacture lipids for COVID-19 vaccine

Optimal storage protocols of wastewater samples for SARS-CoV-2 RNA detection

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging