Gene News and Research

Latest Gene News and Research

Study: Heart problems cause disturbed gene activity in the brain's memory center

Heart problems cause disturbed gene activity in the brain's memory center, from which cognitive deficits arise.

27 Feb 2021

Study finds novel way to diagnose Alzheimer's disease before symptoms occur

Early diagnosis of Alzheimer's disease has been shown to reduce cost and improve patient outcomes, but current diagnostic approaches can be invasive and costly.

26 Feb 2021

NLRP3 inflammasome inhibitors may help treat early COVID-19, says study

A new study by researchers in the U.S. further supports the hypothesis that the unregulated release of inflammatory cytokines is responsible for the local and systemic inflammation that is associated with multi-organ damage and death in severe COVID-19.

26 Feb 2021

A missing protein explains the appearance of tumor cells in people with Mulibrey syndrome

Researchers from the Andalusian Centre for Molecular Biology and Regenerative Medicine (CABIMER), in collaboration with the Swiss Institute for Experimental Cancer Research (ISREC) have studied the mechanisms behind the higher tendency of people with Mulibrey syndrome to develop tumors.

26 Feb 2021

Proteins play crucial role in muscle growth

When a muscle grows, because its owner is still growing too or has started exercising regularly, some of the stem cells in this muscle develop into new muscle cells.

26 Feb 2021

Retroviruses invading the koala germline contribute to high cancer rates

Koalas are facing multiple environmental and health issues which threaten their survival. Along with habitat loss - accelerated by last year’s devastating bush fires – domestic dog attacks and road accidents, they suffer from deadly chlamydial infections and extremely high frequency of cancer.

26 Feb 2021

Catalent to Acquire Delphi Genetics and Launch US Plasmid Manufacturing Site to Establish Global pDNA Development and Manufacturing Capabilities

Catalent and Delphi Genetics today announced that they have entered into a final and definitive agreement whereby Catalent will acquire 100% of the shares of Delphi Genetics.

26 Feb 2021

Catalent to Acquire Delphi Genetics and Launch US Plasmid Manufacturing Site to Establish Global pDNA Development and Manufacturing Capabilities

Catalent and Delphi Genetics today announced that they have entered into a final and definitive agreement whereby Catalent will acquire 100% of the shares of Delphi Genetics.

26 Feb 2021

Immunologists map unknown biological machinery to produce memory T cells

Immunologists at St. Jude Children's Research Hospital have mapped the previously unknown biological machinery by which the immune system generates T cells that kill bacteria, viruses and tumor cells.

26 Feb 2021

Study describes the sequencing of 64 full human genomes

Researchers at the University of Maryland School of Medicine (UMSOM) co-authored a study, published today in the journal Science, that details the sequencing of 64 full human genomes.

26 Feb 2021

New approach can help treat hypertrophic cardiomyopathy with precision medicine

Hypertrophic cardiomyopathy (HCM) is a cardiovascular disease characterized by thickening of the left ventricle, otherwise known as the main squeezing chamber of the heart. HCM is best known for causing sudden death in athletes but can occur in persons of any age, often without symptoms.

26 Feb 2021

Study reveals information about risk genes in schizophrenia

Dr. Felix-Martin Werner, working at the Euro Academy Pößneck in Germany and Prof. Rafael Coveñas, working at the Institute of Neurosciences of Castilla and León, Salamanca in Spain, have been working on neurological and psychiatric disease for over ten years.

26 Feb 2021

CRISPR screen identifies clinically approved immunosuppressants that could treat coronavirus infections

Researchers in Switzerland and Germany have identified host cell factors required for coronavirus replication that could serve as targets for treatment with clinically-approved drugs.

25 Feb 2021

Study shows direct connection between the gut microbiome and Alzheimer's-like behavior

New research in mice published today in the journal Scientific Reports strengthens the growing scientific consensus regarding the role of the gut microbiome in neurodegenerative disorders including Alzheimer's disease.

25 Feb 2021

FDA approval provides targeted treatment option for patients with rare DMD mutation

Today, the U.S. Food and Drug Administration granted approval for Amondys 45 (casimersen) injection for the treatment of Duchenne muscular dystrophy (DMD) in patients who have a confirmed mutation of the DMD gene that is amenable to exon 45 skipping (Exons are pieces of DNA that provide information for making proteins in a person's genome).

25 Feb 2021

World's largest study of genetic factors reveals link between depression and stomach ulcers

University of Queensland researchers have confirmed a link between depression and stomach ulcers, in the world's largest study of genetic factors in peptic ulcer disease.

25 Feb 2021

SARS-CoV-2 ORF7a mutation limits host immune suppression, finds study

Researchers have identified a high variability in the C-terminal end of ORF7a in SARS-CoV-2 sequences collected from around the globe. They noted that mutations result in a defective suppression of interferon and lowered replication rate.

25 Feb 2021

Canadian pilot study uses gene therapy to successfully treat patients with Fabry disease

Results of a world-first Canadian pilot study on patients treated with gene therapy for Fabry disease show that the treatment is working and safe.

25 Feb 2021

Study explores individual differences of SARS-CoV-2 infection in ACE2-expressing stem cells

The clinical phenotype of COVID-19, caused by SARS-CoV-2, is remarkable for its wide range of severity among individual patients. Genetic variations are known to mediate part of these differences. To examine these differences, researchers in a new study used human induced pluripotent stem cells (iPSCs) from different genetically diverse individuals. These cells are used to model genetic disease since they contain the donor’s genetic information. Researchers use a panel of iPSCs from over 500 individuals. The researchers preferred undifferentiated iPSCs to reduce the time required to differentiate them, especially since infection is not always reliable.

25 Feb 2021

Study provides new insight into the genetics of coronary artery disease

According to a new study published in The American Journal of Human Genetics, more than one third of genetic variants that increase the risk of coronary artery disease regulate the expression of genes in the liver. These variants have an impact on the expression of genes regulating cholesterol metabolism, among other things.

25 Feb 2021

Gene News and Research

Latest Gene News and Research

Study: Heart problems cause disturbed gene activity in the brain's memory center

Study finds novel way to diagnose Alzheimer's disease before symptoms occur

NLRP3 inflammasome inhibitors may help treat early COVID-19, says study

A missing protein explains the appearance of tumor cells in people with Mulibrey syndrome

Proteins play crucial role in muscle growth

Retroviruses invading the koala germline contribute to high cancer rates

Catalent to Acquire Delphi Genetics and Launch US Plasmid Manufacturing Site to Establish Global pDNA Development and Manufacturing Capabilities

Catalent to Acquire Delphi Genetics and Launch US Plasmid Manufacturing Site to Establish Global pDNA Development and Manufacturing Capabilities

Immunologists map unknown biological machinery to produce memory T cells

Study describes the sequencing of 64 full human genomes

New approach can help treat hypertrophic cardiomyopathy with precision medicine

Study reveals information about risk genes in schizophrenia

CRISPR screen identifies clinically approved immunosuppressants that could treat coronavirus infections

Study shows direct connection between the gut microbiome and Alzheimer's-like behavior

FDA approval provides targeted treatment option for patients with rare DMD mutation

World's largest study of genetic factors reveals link between depression and stomach ulcers

SARS-CoV-2 ORF7a mutation limits host immune suppression, finds study

Canadian pilot study uses gene therapy to successfully treat patients with Fabry disease

Study explores individual differences of SARS-CoV-2 infection in ACE2-expressing stem cells

Study provides new insight into the genetics of coronary artery disease

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Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

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