Gene News and Research

Latest Gene News and Research

Could rotavirus vaccine platforms aid in the immunization campaign against SARS-CoV-2?

The study began with the generation of recombinant (r)SA11 rotaviruses, into which segment 7 modified RNAs were introduced. These encoded sequences for the non-structural protein NSP3 and some parts of the viral spike.

23 Feb 2021

DNA origami used to analyze the ultra-fast movements of CRISPR enzymes

The remarkable genetic scissors called CRISPR/Cas9, the discovery that won the 2020 Nobel Prize in Chemistry, sometimes cut in places that they are not designed to target.

23 Feb 2021

Study findings help explain the diversity of cancers in different Li-Fraumeni patients

The most frequently mutated gene in human cancers is called p53. Patients with Li-Fraumeni syndrome, which is a rare disorder that increases the risk of developing several types of cancer, often have an increased risk to develop cancers at early ages if they inherit p53 mutations.

23 Feb 2021

Researchers investigate how CF patients respond to COVID-19

So far, based on clinical data, patients with cystic fibrosis (CF) don't appear to be especially susceptible to COVID-19, and when they do get infected, they don't seem to get sicker. But Ruobing (Ruby) Wang, MD, a physician-scientist in the Division of Pulmonary Medicine at Boston Children's Hospital, cares for patients with CF and thinks there is more to the story.

23 Feb 2021

Study shows how m6A regulators influence metabolic heterogeneity of hepatocellular carcinoma

Cancer cells acquire growth advantages over normal cells in myriad ways. Changes in cell programming allow these cells to grow in an uncontrolled fashion, thereby forming the cancer mass.

23 Feb 2021

Genetic mechanism enables TB-causing bacterium to remember and rapidly respond to stress

Tuberculosis bacteria have evolved to remember stressful encounters and react quickly to future stress, according to a study by computational bioengineers at Rice University and infectious disease experts at Rutgers New Jersey Medical School (NJMS).

22 Feb 2021

Researchers expand understanding of hop genome with implications for brewing industry

Oregon State University and U.S. Department of Agriculture researchers have significantly expanded the understanding of the hop genome, a development with important implications for the brewing industry and scientists who study the potential medical benefits of hops.

22 Feb 2021

Study reveals mechanism for translation of maternally inherited mitochondrial genome

An international collaboration among researchers from Finland, Sweden, UK and the USA has captured ribosomes translating messenger RNA expressed from the maternally inherited mitochondrial genome.

22 Feb 2021

HIV-positive people with severe immunosuppression, APOE4 gene may have increased risk for dementia

People living with the human immunodeficiency virus (HIV) who have a history of severe immunosuppression and at least one copy of the Alzheimer's disease-related gene variant APOE4, might see a compounded adverse effect on the circuitry that impacts memory.

22 Feb 2021

POU1F1 gene variant linked to pituitary dwarfism in Karelian Bear Dogs

A study carried out at the University of Helsinki investigated pituitary dwarfism in Karelian Bear Dogs and found a link to a variant of the POU1F1 gene. The results can also help understand the gene's significance to the human pituitary gland's development and function.

22 Feb 2021

Scientists find new therapeutic approach to effectively treat age-related macular degeneration

Runt-related transcription factor 1 (RUNX1) has been linked to retinal neovascularization and the development of abnormal blood vessels, which result in vision loss in diabetic retinopathy.

22 Feb 2021

Novel vectors reduce the risks associated with ocular gene therapies

Strategies based on the use of gene therapy to mitigate the effects of mutations that cause blindness are undergoing rapid development.

22 Feb 2021

Study illuminates the role of HAND2 gene in timing of human labor

A new study illuminates how a gene called HAND2 may have a hand in the timing of human labor.

22 Feb 2021

Children exposed to air pollution may be at higher risk of disease in adulthood

Children exposed to air pollution, such as wildfire smoke and car exhaust, for as little as one day may be doomed to higher rates of heart disease and other ailments in adulthood, according to a new Stanford-led study.

22 Feb 2021

Neanderthal gene can confer protection against severe COVID-19, finds study

A new study has detailed how some of the genes in the human genome inherited from Neanderthals appear to confer a protective effect against severe COVID-19.

22 Feb 2021

Rest during holidays has a restorative effect on DNA changes in shift workers with sleep disorder

Long-term sleep deprivation is detrimental to health, increasing the risk of psychiatric and somatic disorders, such as depression and cardiovascular diseases.

22 Feb 2021

Could an intranasal adjuvant to vaccines boost immunity against SARS-CoV-2 variants?

A research team from the University of Michigan Medical School, USA, developed a supplementary intranasal treatment to improve COVID-19 vaccine response and its effects on long-lasting immunity from other variants, such as the B.1.351 variant first found in South Africa.

22 Feb 2021

Study identifies immune profile of people with severe COVID-19

A team of researchers at Georgetown University Medical Center, USA, investigated how SARS-CoV-2 affects the immune system’s response during and after infection and contributes to the severity of COVID-19.

22 Feb 2021

Mucosal delivery of IFNs a good strategy for COVID-19 prophylaxis post-exposure

Researchers from the UK and Germany recently reported a comprehensive characterization of the SARS-CoV-2 response of human nasal epithelial cells, revealing a response dominated by IFN-I/IIIs. Also, recombinant IFN-I/III treatment was found to efficiently block the replication of SARS-CoV-2, which suggests that mucosal delivery of IFNs may be a good strategy for prophylaxis post-exposure.

22 Feb 2021

Eating low-quality diet during pregnancy is linked to late-childhood obesity

Eating a low quality diet, high in foods and food components associated with chronic inflammation, during pregnancy may be associated with an increased risk of obesity and excess body fat in children, especially during late-childhood. The findings are published the open access journal BMC Medicine.

21 Feb 2021

Gene News and Research

Latest Gene News and Research

Could rotavirus vaccine platforms aid in the immunization campaign against SARS-CoV-2?

DNA origami used to analyze the ultra-fast movements of CRISPR enzymes

Study findings help explain the diversity of cancers in different Li-Fraumeni patients

Researchers investigate how CF patients respond to COVID-19

Study shows how m6A regulators influence metabolic heterogeneity of hepatocellular carcinoma

Genetic mechanism enables TB-causing bacterium to remember and rapidly respond to stress

Researchers expand understanding of hop genome with implications for brewing industry

Study reveals mechanism for translation of maternally inherited mitochondrial genome

HIV-positive people with severe immunosuppression, APOE4 gene may have increased risk for dementia

POU1F1 gene variant linked to pituitary dwarfism in Karelian Bear Dogs

Scientists find new therapeutic approach to effectively treat age-related macular degeneration

Novel vectors reduce the risks associated with ocular gene therapies

Study illuminates the role of HAND2 gene in timing of human labor

Children exposed to air pollution may be at higher risk of disease in adulthood

Neanderthal gene can confer protection against severe COVID-19, finds study

Rest during holidays has a restorative effect on DNA changes in shift workers with sleep disorder

Could an intranasal adjuvant to vaccines boost immunity against SARS-CoV-2 variants?

Study identifies immune profile of people with severe COVID-19

Mucosal delivery of IFNs a good strategy for COVID-19 prophylaxis post-exposure

Eating low-quality diet during pregnancy is linked to late-childhood obesity

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging