Gene News and Research

Latest Gene News and Research

Optimal antibody combinations and Fc binding inhibit SARS-CoV-2 in vivo

A recent study by researchers at the University of North Carolina at Chapel Hill and The Rockefeller University and published on the preprint server bioRxiv in September 2020 shows that a combination of neutralizing antibodies with intact Fc effector function can effectively reduce the viral load and prevent infection.

17 Sep 2020

ERS Genomics and Applied StemCell sign agreement on commercialization of CRISPR gene editing tools

ERS Genomics Limited, which was formed to provide broad access to the foundational CRISPR/Cas9 intellectual property (IP) co-owned by Dr. Emmanuelle Charpentier, today announced it has signed an agreement with Applied StemCell, Inc., a leading provider of stem cell, animal model, antibody discovery services and reagents.

17 Sep 2020

Study implicates new gene as driver of motor neuron diseases

Failures in a quality control system that protects protein-building fidelity in cells can lead to motor neuron degeneration and related diseases, according to a new study from an international team co-directed by Scripps Research molecular biologist Claudio Joazeiro, PhD.

16 Sep 2020

Researchers compare developed carriers for delivery of genome editing tools with existing analogs

Researchers from Peter the Great St.Petersburg Polytechnic University in collaboration with colleagues from the Pavlov University, ITMO University, and the University of Hamburg compared their developed carriers for delivery of genome editing (GE) tools with other available analogs.

16 Sep 2020

UC Davis uses microneedles to deliver gene therapy for retinal diseases

A novel approach to delivering gene therapy for retinal diseases eliminates the need for complex eye surgery and treats more damaged cells than existing methods, a team of UC Davis physicians and veterinary eye specialists has found.

16 Sep 2020

Study provides insight into lymphomagenesis and patterns of resistance to immunotherapy

Lymphomas are a diverse group of cancers of the immune system, which is the body's primary defense against autoimmune disease, infections, and malignancy.

16 Sep 2020

Curi Bio Announces Mantarray™ Platform for Analysis of 3D Engineered Muscle Tissues for Discovery of New Therapeutics

Curi Bio today announced the Mantarray™ platform for human-relevant 3D engineered muscle tissue (EMT) analysis.

From Curi Bio 16 Sep 2020

Study provides valuable insights on effects of APOE gene on health and disease

From Alzheimer's to obesity, life can change dramatically if you discover you have a genetic risk of disease. Now, a new study from the Australian Centre for Precision Health, University of South Australia is challenging these predispositions, showing that some of the genes traditionally labelled as 'bad' are not always what they seem.

16 Sep 2020

Study highlights role of specific protein in the mass production of antibodies

Antibodies play a fundamental role in medicine, and antibody-mediated immune response is the ultimate target in the quest for a vaccine to defeat the current pandemic.

16 Sep 2020

Genetic risk factor for late-onset Alzheimer's disease has early effects on the brain

A genetic predisposition to late-onset Alzheimer's disease affects how the brains of young adults cope with certain memory tasks.

15 Sep 2020

Study uncovers a promising new therapeutic approach for Duchenne muscular dystrophy

Scientists at Sanford Burnham Prebys Medical Discovery Institute, Fondazione Santa Lucia IRCCS, and Università Cattolica del Sacro Cuore in Rome have shown that pharmacological (drug) correction of the content of extracellular vesicles released within dystrophic muscles can restore their ability to regenerate muscle and prevent muscle scarring (fibrosis).

15 Sep 2020

LRRK2 enzyme suppresses protein synthesis in Parkinson’s disease

In a recently published study, researchers from the Turku Bioscience Centre at the University of Turku and Åbo Akademi University in Finland monitored the production of new proteins as they were produced by the cells' protein building machinery, the ribosome.

15 Sep 2020

Scientists unlock crucial molecular details regarding tau's activity

Frontotemporal lobar degeneration (FTLD) is a type of dementia that appears earlier in life than Alzheimer's disease (AD).

15 Sep 2020

Scientists unravel the molecular mechanism underlying the causes of colorectal cancer

A team of scientists has unraveled the molecular mechanism behind one of the causes of colorectal cancer, and a treatment target.

15 Sep 2020

Researchers identify specific potential therapeutic targets for aggressive form of pancreatic cancer

A team of researchers led by Mayo Clinic and the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, has identified specific potential therapeutic targets for the most aggressive and lethal form of pancreatic cancer.

15 Sep 2020

Evonetix partners with Analog Devices to fast track the development of DNA desktop writer

EVONETIX LTD, the synthetic biology company developing a desktop platform for scalable, high-fidelity and rapid gene synthesis, today announced a collaboration with leading, global high-performance analog technology company, Analog Devices, Inc.

15 Sep 2020

Central nervous system immune responses to COVID-19

A recent study published on the preprint server bioRxiv by scientists from Yale School of Medicine, University of California, Yale School of Public Health, Yale University, and Howard Hughes Medical Institute examined the impact of SARS-CoV-2 infection on the central nervous system.

14 Sep 2020

RCas9 gene therapy clears toxic RNA buildup in mouse model of myotonic dystrophy

Myotonic dystrophy type I is the most common type of adult-onset muscular dystrophy. People with the condition inherit repeated DNA segments that lead to the toxic buildup of repetitive RNA, the messenger that carries a gene's recipe to the cell's protein-making machinery.

14 Sep 2020

Tiny antibody component shows high potency in SARS-CoV-2 animal models

University of Pittsburgh School of Medicine scientists have isolated the smallest biological molecule to date that completely and specifically neutralizes the SARS-CoV-2 virus, which is the cause of COVID-19.

14 Sep 2020

Circadian rhythm affects SARS-CoV-2 infection and host immune response

In an interesting bioRxiv preprint paper, French researchers show that the time day can affect infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as well as guide subsequent host immune response – implying that circadian rhythm may well be a novel target for managing viral progression.

14 Sep 2020

Gene News and Research

Latest Gene News and Research

Optimal antibody combinations and Fc binding inhibit SARS-CoV-2 in vivo

ERS Genomics and Applied StemCell sign agreement on commercialization of CRISPR gene editing tools

Study implicates new gene as driver of motor neuron diseases

Researchers compare developed carriers for delivery of genome editing tools with existing analogs

UC Davis uses microneedles to deliver gene therapy for retinal diseases

Study provides insight into lymphomagenesis and patterns of resistance to immunotherapy

Curi Bio Announces Mantarray™ Platform for Analysis of 3D Engineered Muscle Tissues for Discovery of New Therapeutics

Study provides valuable insights on effects of APOE gene on health and disease

Study highlights role of specific protein in the mass production of antibodies

Genetic risk factor for late-onset Alzheimer's disease has early effects on the brain

Study uncovers a promising new therapeutic approach for Duchenne muscular dystrophy

LRRK2 enzyme suppresses protein synthesis in Parkinson’s disease

Scientists unlock crucial molecular details regarding tau's activity

Scientists unravel the molecular mechanism underlying the causes of colorectal cancer

Researchers identify specific potential therapeutic targets for aggressive form of pancreatic cancer

Evonetix partners with Analog Devices to fast track the development of DNA desktop writer

Central nervous system immune responses to COVID-19

RCas9 gene therapy clears toxic RNA buildup in mouse model of myotonic dystrophy

Tiny antibody component shows high potency in SARS-CoV-2 animal models

Circadian rhythm affects SARS-CoV-2 infection and host immune response

eBook: Using iPSCs models for human disease research and drug discovery eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging