Gene News and Research

Latest Gene News and Research

Scientists uncover why developing nerve cells take a wrong turn

A group of scientists from CECAD, the Cluster of Excellence 'Cellular Stress Responses in Aging-Associated Diseases,' have found a mechanism by which neurodevelopmental diseases concerning neurons can be explained: The loss of a certain enzyme, UBE2K, impeded the differentiation of stem cells by silencing the expression of genes important for neuronal differentiation and, therefore, the development and generation of neurons.

3 Jun 2020

Genetic variations linked to COVID-19 severity

A new report by researchers from Thailand's Mahidol University and published on the preprint server medRxiv in May 2020 reports that the clinical severity of COVID-19 may be linked to the genetic makeup of the patient in addition to external factors.

3 Jun 2020

Study sheds new light on how respiratory virus breaks into cells to cause infection

New research from University of Alberta microbiologists has shed new light on how the respiratory syncytial virus (RSV)--one of the most common viral infections--breaks into our cells to cause infection.

3 Jun 2020

Blood group type may affect susceptibility to COVID-19 respiratory failure

A group of over 120 researchers from various institutions across Europe has performed the first genome-wide association study to reveal host genetic factors that may contribute to respiratory failure in cases of coronavirus disease 209 (COVID-19).

3 Jun 2020

New test identifies CAD-affected children who may benefit from uridine

Scientists at Sanford Burnham Prebys Medical Discovery Institute and the Centro de Biología Molecular Severo Ochoa in Spain have created a test that determines which children with CAD deficiency - a rare metabolic disease - are likely to benefit from receiving uridine, a nutritional supplement that has dramatically improved the lives of other children with the condition.

3 Jun 2020

Researchers discover key gene essential for survival of leukemia stem cells

Acute myeloid leukemia (AML) is one of the most common forms of blood cancer among adults and is associated with a low survival rate, and leads to the inhibition of normal blood formation.

3 Jun 2020

Researchers examine the role of two genes that cause triple-negative breast cancer

Researchers at Tulane University School of Medicine identified a gene that causes an aggressive form of breast cancer to rapidly grow.

3 Jun 2020

Sample inactivation may contribute to false-negative rate of SARS-Cov-2

To protect medical laboratory personnel from infection when testing clinical samples for SARS-CoV-2, most laboratories inactivate the virus before testing.

3 Jun 2020

Despite landscape obstacles, pronghorn exhibit little genetic variation

A University of Wyoming researcher led a study that showed Wyoming pronghorn exhibit little-to-no population genetic differentiation even though their range spans hundreds of kilometers, multiple mountain ranges, and three major interstate highways.

3 Jun 2020

A vectored vaccine candidate against SARS-CoV-2

The current pandemic of COVID-19 is caused by the severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2), a betacoronavirus similar to that which caused the SARS-CoV and MERS-CoV earlier. Scientists are pursuing therapeutic drugs and vaccines to counter the relentless spread of the virus, but so far, none has been established to be effective. However, several are in clinical trials in various parts of the world.

2 Jun 2020

Study reveals how a fat cell's immune response worsens obesity

When obesity occurs, a person's own fat cells can set off a complex inflammatory chain reaction that can further disrupt metabolism and weaken immune response--potentially placing people at higher risk of poor outcomes from a variety of diseases and infections, including COVID-19.

2 Jun 2020

New advance addresses a big challenge with using CRISPR in cancer patients

A mutation unique to certain cancer tumors is a potential homing beacon for safely deploying CRISPR gene editing enzymes to disarm DNA that makes cancer cells resistant to treatment, while ignoring the gene in normal cells where it's critical to healthy function, according to a new study from ChristianaCare's Gene Editing Institute in the journal Molecular Cancer Research.

2 Jun 2020

Expression of certain genes may play role in susceptibility to PTSD

Results from a new study suggest that whether certain genes are expressed -- turned on or off-- may play a role in susceptibility to post-traumatic stress disorder.

2 Jun 2020

Explosion of immune cells in mouse lungs after birth may help protect against infections

An explosion in the number and types of immune cells in the lungs of newborn mice likely helps them adapt to breathing and protects them from infection, says a new study published today in eLife.

2 Jun 2020

CSL Behring and Seattle Children's partner to develop gene therapies for primary immunodeficiency diseases

Seattle Children's Research Institute, one of the top pediatric research institutions in the world, and global biotechnology leader CSL Behring announced a strategic alliance to develop stem cell gene therapies for primary immunodeficiency diseases.

2 Jun 2020

Gene discovery in fruit flies could lead to treatments for age-related hearing loss

Scientists at UCL have discovered sets of regulatory genes, which are responsible for maintaining healthy hearing. The finding, made in fruit flies, could potentially lead to treatments for age-related hearing loss (ARHL) in humans.

2 Jun 2020

Microperimetry can help determine the efficacy of novel treatments for macular diseases

Stargardt disease is an inherited eye disease. Its onset is typically in adolescence and it is among the leading causes of blindness in this age group. Symptoms range from severe loss of sharp vision to almost complete loss of sight.

2 Jun 2020

Study identifies gene that causes eye loss in cavefish

Mexican cavefish spend their entire lives in the dark. With no need for vision, many of them lost functional eyes.

2 Jun 2020

Ciheb awarded $4 million to support COVID-19 response activities

The Center for International Health, Education and Biosecurity at the University of Maryland School of Medicine's Institute of Human Virology was awarded $4 million from the U.S. Centers for Disease Control and Prevention to support coronavirus disease 2019 (COVID-19) response activities in Botswana, Nigeria, Malawi, and Mozambique.

2 Jun 2020

Does interferon therapy work in COVID-19?

A new study published on the preprint site medRxiv in May 2020 reports on the efficacy of interferons in treating COVID-19. The research could help evaluate the place of such therapy in the management of this disease.

2 Jun 2020

Gene News and Research

Latest Gene News and Research

Scientists uncover why developing nerve cells take a wrong turn

Genetic variations linked to COVID-19 severity

Study sheds new light on how respiratory virus breaks into cells to cause infection

Blood group type may affect susceptibility to COVID-19 respiratory failure

New test identifies CAD-affected children who may benefit from uridine

Researchers discover key gene essential for survival of leukemia stem cells

Researchers examine the role of two genes that cause triple-negative breast cancer

Sample inactivation may contribute to false-negative rate of SARS-Cov-2

Despite landscape obstacles, pronghorn exhibit little genetic variation

A vectored vaccine candidate against SARS-CoV-2

Study reveals how a fat cell's immune response worsens obesity

New advance addresses a big challenge with using CRISPR in cancer patients

Expression of certain genes may play role in susceptibility to PTSD

Explosion of immune cells in mouse lungs after birth may help protect against infections

CSL Behring and Seattle Children's partner to develop gene therapies for primary immunodeficiency diseases

Gene discovery in fruit flies could lead to treatments for age-related hearing loss

Microperimetry can help determine the efficacy of novel treatments for macular diseases

Study identifies gene that causes eye loss in cavefish

Ciheb awarded $4 million to support COVID-19 response activities

Does interferon therapy work in COVID-19?

eBook: Using iPSCs models for human disease research and drug discovery eBook

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