Gene News and Research

Latest Gene News and Research

Study highlights triptolide as valuable therapeutic approach for IDH1-mutated glioma

Findings of a new study led by Prof. XU Guowang from the Dalian Institute of Chemical Physics of the Chinese Academy of Sciences and Prof. YANG Chunzhang from the National Cancer Institute shed light on the selective therapeutics for IDH1-mutated glioma by targeting glutathione synthesis pathway.

13 Apr 2020

Reprimo gene may play a role in menopause-related weight gain

A new study published in the journal Nature Metabolism in April 2020 indicates that some genes could allow women in menopause to remain healthy without hormone replacement therapy, which has been linked to a higher risk of heart disease and breast cancer.

13 Apr 2020

Toxic cell atlas can guide discovery of new drugs for neurodegeneration

A common thread in many inflammatory and neurodegenerative diseases, including multiple sclerosis (MS), is damage caused by oxidative stress. Oxidative stress occurs when cells produce toxic substances known as reactive oxygen species, which are damaging nerve cells and other cells in the body.

13 Apr 2020

CRISPR may help in kidney-transplants by detecting viruses

An exciting new study published in the journal Nature Biomedical Engineering in April 2020 reports excellent results with a new test for two common viruses that infect kidney transplant patients. The levels of these viruses shoot up during the acute phase of rejection.

13 Apr 2020

Stanford scientists find gene variant that staves off Alzheimer's in some people

Stanford Medicine researchers have found a gene variant that protects carriers of another gene variant, ApoE4, from developing Alzheimer’s disease — the first demonstration of that beneficial effect.

13 Apr 2020

New Vietnamese enterovirus C4 strains possibly more virulent than B5 strains

A new study published in January 2020 in the journal Scientific Reports reports the presence of a new lineage of enterovirus responsible for the hand-foot-and-mouth disease (HFMD). They think this could be more virulent than the earlier B5 subtype.

12 Apr 2020

First detailed map of transcriptome and epitranscriptome for novel coronavirus (SARS-CoV-2)

A team of researchers has come out with the first detailed map of the transcriptome and epitranscriptome of the virulent SARS-CoV-2 that causes COVID-19 disease, the illness that has become a pandemic ravaging both developed and less developed countries of the world. The study, published in the journal Cell in April 2020, may assist in the development of new vaccines and therapeutics.

12 Apr 2020

PARP inhibitor drugs can be structurally modified to better kill tumor cells

A prospective "PARP inhibitor" drug that has struggled to show effectiveness in clinical trials against cancers can be structurally modified to greatly increase its power to kill tumor cells, researchers from Penn Medicine report this week in Science.

12 Apr 2020

Researchers identify new risk gene for Parkinson's disease

Screening DNA of Parkinson's patients in the Christine Van Broeckhoven laboratory (VIB-UAntwerpen Center for Molecular Neurology) identified a new risk gene for Parkinson's disease. Mutations in ATP10B resulted in loss of ATP10B protein.

12 Apr 2020

Scientists make plant genome public to help combat COVID-19

Plant Nicotiana benthamiana is currently used as a bio-factory for several experimental vaccines against SARS-COV-2.

11 Apr 2020

Researchers pinpoint genetic variation responsible for development of IBD

Researchers at Children's Hospital of Philadelphia have pinpointed a genetic variation responsible for driving the development of inflammatory bowel disease.

9 Apr 2020

Combination of rare, damaging mutations negatively affects healthspan and longevity

Scientists report that the combined effects of rare, damaging mutations present at birth have a negative impact on healthspan and longevity, according to a study published this week in eLife.

9 Apr 2020

Researchers identify protein that plays critical role in cancer treatment-related heart damage

Many cancers can be successfully treated, but treatment itself often comes with risks as well. Cancer therapy that uses anthracyclines--a class of commonly used chemotherapy drugs--has been associated with heart damage that can eventually result in heart failure. It is thought to be the reason why heart disease is a leading cause of death in cancer survivors, immediately following cancer recurrence.

9 Apr 2020

Missing BAP1 gene renders immunotherapies ineffectual in uveal melanomas

New study from researchers in Finland and the United Kingdom reveals that tumors lacking a protein called BAP1 have an ineffective immune reaction against cancer, thus rendering immunotherapies ineffectual, particularly in uveal melanomas.

9 Apr 2020

Researchers discover novel role for dopamine that impacts gene expression related to cocaine abuse

A new role for dopamine independent of classic neurotransmission may be critical gene expression changes related to cocaine use.

9 Apr 2020

Novel coronavirus targets specific secretory cells in the lungs

Viruses attack specific host cells, which can cause chaos in the body. The novel coronavirus, now called severe acute respiratory syndrome coronavirus 2 or SARS-CoV-2 for short, infects respiratory epithelial cells in the lining of the lung, causing difficulty of breathing. The usual cause of death of those who contract the virus is pneumonia and acute respiratory distress syndrome (ARDS). Now, a new study has found that SARS-CoV-2 specifically attack certain progenitor cells called bronchial transient secretory cells in the lungs.

9 Apr 2020

LGC launches new proficiency testing program for SARS-CoV-2 detection

LGC today launched a Proficiency Testing service for the detection of SARS-CoV-2 (COVID 19) by nucleic acid amplification testing, one of the first global schemes for COVID-19.

From ATCC 9 Apr 2020

Smokers have more ACE2 receptors making it easier for SARS-CoV-2 to infect

A new study published in the European Respiratory Journal in April 2020 reveals that people with smoking-damaged lungs and those with chronic obstructive pulmonary disease (COPD) are likely to have a higher level of the angiotensin-converting enzyme II (ACE2).

9 Apr 2020

PIV5-based MERS vaccine shows promise for COVID-19

The coronavirus disease (COVID-19) has spread to 184 countries and territories. Currently, there is no vaccine available for COVID-19 disease, or SARS-CoV-2 infection. However, scientists around the world are racing to find ways to block the virus.

8 Apr 2020

Researchers develop online resource to refine results from RNA sequencing

DNA sequencing is becoming a more commonplace method for detecting diseases and improving precision medicine.

8 Apr 2020

Gene News and Research

Latest Gene News and Research

Study highlights triptolide as valuable therapeutic approach for IDH1-mutated glioma

Reprimo gene may play a role in menopause-related weight gain

Toxic cell atlas can guide discovery of new drugs for neurodegeneration

CRISPR may help in kidney-transplants by detecting viruses

Stanford scientists find gene variant that staves off Alzheimer's in some people

New Vietnamese enterovirus C4 strains possibly more virulent than B5 strains

First detailed map of transcriptome and epitranscriptome for novel coronavirus (SARS-CoV-2)

PARP inhibitor drugs can be structurally modified to better kill tumor cells

Researchers identify new risk gene for Parkinson's disease

Scientists make plant genome public to help combat COVID-19

Researchers pinpoint genetic variation responsible for development of IBD

Combination of rare, damaging mutations negatively affects healthspan and longevity

Researchers identify protein that plays critical role in cancer treatment-related heart damage

Missing BAP1 gene renders immunotherapies ineffectual in uveal melanomas

Researchers discover novel role for dopamine that impacts gene expression related to cocaine abuse

Novel coronavirus targets specific secretory cells in the lungs

LGC launches new proficiency testing program for SARS-CoV-2 detection

Smokers have more ACE2 receptors making it easier for SARS-CoV-2 to infect

PIV5-based MERS vaccine shows promise for COVID-19

Researchers develop online resource to refine results from RNA sequencing

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging