Gene News and Research

Latest Gene News and Research

Novel immunotherapy targeting myeloid immune cells reduces tumor growth

Checkpoint inhibitors, a type of immunotherapy, that target myeloid immune cells and slow tumor growth were discovered by a team from the Perelman School of Medicine at the University of Pennsylvania and other institutions.

27 May 2020

Findings provide new insights into future cancer treatment

An early age of pregnancy (25 years and younger) is known to reduce the overall risk of breast cancer by over 30%. CSHL Assistant Professor Camila dos Santos spent several years teasing out the molecular details behind the protective effects of pregnancy.

27 May 2020

A new approach to predict the evolutionary mechanisms of melanoma

Melanoma is a malignant tumour resulting from the transformation of melanocytes, the cells in the skin that undertake to synthesise melanin, a complex polymer which protects us from the negative effects of solar radiation.

27 May 2020

Researchers investigate the early development of ovarian cancer

Researchers from the group of Hans Clevers at the Hubrecht Institute have modeled the development and progression of high-grade serous ovarian cancer in mini-versions of the female reproductive organs of the mouse.

27 May 2020

Stand Up To Cancer hails FDA approval of new treatment option for aggressive prostate cancer

A recent FDA approval supported by Stand Up To Cancer research provides a new treatment option for patients with an aggressive form of prostate cancer.

27 May 2020

Research could help identify disturbances in the body's copper metabolism

In biology it is well-known that every living organism is triggered by the hereditary material or DNA that encodes various protein molecules, which in turn perform all the necessary biological functions and it might seem that nothing else is needed to sustain the life of an organism.

26 May 2020

A key player in hepatitis A virus infection discovered

How hepatitis A virus manages to enter liver cells called hepatocytes and initiate infection had remained a mystery for fifty years until now.

26 May 2020

UVA researchers discover essential key to hearing sensitivity in the inner ear

New research from the University of Virginia School of Medicine is shedding light on the biological architecture that lets us hear – and on a genetic disorder that causes both deafness and blindness.

26 May 2020

Collagen maturation regulates PEDF availability, study shows

Cells are like tiny self-contained machines that are constantly fine-tuned in response to both internal and external signals. Some of these signals are induced by extracellular ligands, specialized proteins that bind to specific receptors on the cell surface, stimulating signaling pathways and altering gene expression.

26 May 2020

Study shows antihypertensive drugs do not raise serum levels of ACE2

A new study published on the preprint server medRxiv* by researchers from Iceland and the U.S. shows how treatment with angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs) does not raise angiotensin-converting enzyme 2 (ACE2) levels in human serum – and cautions against the discontinuation of these drugs among patients affected with coronavirus disease (COVID-19).

26 May 2020

Minuscule tracking devices give unprecedented peek into how cells change with time

For the first time, scientists have introduced minuscule tracking devices directly into the interior of mammalian cells, giving an unprecedented peek into the processes that govern the beginning of development.

26 May 2020

Novel testing system predicts outcomes in patients with sepsis

More than 1.7 million Americans develop sepsis each year, and more than 270,000 die from it. The condition--which happens when the body has an extreme response to a bacterial or viral infection, causing a chain reaction that can lead to organ failure and death--has few strategies for treatment.

26 May 2020

New NIH grant will help Pennington Biomedical scientists to study metabolic diseases

A new federal grant will allow young scientists to delve into the mechanisms of emotional eating and preeclampsia and other disorders not considered "classic" metabolic diseases.

26 May 2020

New study reveals complex role of immune-system molecule in Huntington's disease

More than a decade before people with Huntington's disease show symptoms, they can exhibit abnormally high levels of an immune-system molecule called interleukin-6 (IL-6), which has led many researchers to suspect IL-6 of promoting the eventual neurological devastation associated with the genetic condition.

26 May 2020

3D model displays arrangement of intrinsic neurons in the rat heart

An interdisciplinary team of researchers has developed a virtual 3D heart, digitally showcasing the heart's unique network of neurons for the first time.

26 May 2020

Women with Neandertal gene have increased fertility

One in three women in Europe inherited the receptor for progesterone from Neandertals - a gene variant associated with increased fertility, fewer bleedings during early pregnancy and fewer miscarriages.

26 May 2020

New technique for fast, easy optimization of antibodies using chicken cells

Antibodies for potential use as medicines can be made rapidly in chicken cells grown in laboratories. Researchers refer to their technique as the human ADLib system, short for autonomously diversifying libraries.

26 May 2020

Rejuvenated fibroblasts could be used in regenerative medicine, stem cell engineering

Fibroblasts are the most common connective tissue cells. They produce the structural framework for animal tissues, synthesize the extracellular matrix and collagen, and play a critical role in wound healing.

26 May 2020

Researchers identify genetic mechanisms that produce radioresistance in cancer cells

Cancer stem cells are a cell type that was previously little known. They are resistant to irradiation and prevent the effective treatment of many types of cancer. A research group from Innsbruck has now identified two genetic mechanisms that produce this radioresistance.

26 May 2020

Genes associated with dementia doubles the risk of developing severe COVID-19

Having a faulty gene linked to dementia doubles the risk of developing severe COVID-19, according to a large-scale study.

26 May 2020

Gene News and Research

Latest Gene News and Research

Novel immunotherapy targeting myeloid immune cells reduces tumor growth

Findings provide new insights into future cancer treatment

A new approach to predict the evolutionary mechanisms of melanoma

Researchers investigate the early development of ovarian cancer

Stand Up To Cancer hails FDA approval of new treatment option for aggressive prostate cancer

Research could help identify disturbances in the body's copper metabolism

A key player in hepatitis A virus infection discovered

UVA researchers discover essential key to hearing sensitivity in the inner ear

Collagen maturation regulates PEDF availability, study shows

Study shows antihypertensive drugs do not raise serum levels of ACE2

Minuscule tracking devices give unprecedented peek into how cells change with time

Novel testing system predicts outcomes in patients with sepsis

New NIH grant will help Pennington Biomedical scientists to study metabolic diseases

New study reveals complex role of immune-system molecule in Huntington's disease

3D model displays arrangement of intrinsic neurons in the rat heart

Women with Neandertal gene have increased fertility

New technique for fast, easy optimization of antibodies using chicken cells

Rejuvenated fibroblasts could be used in regenerative medicine, stem cell engineering

Researchers identify genetic mechanisms that produce radioresistance in cancer cells

Genes associated with dementia doubles the risk of developing severe COVID-19

eBook: Using iPSCs models for human disease research and drug discovery eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting