Gene News and Research

Latest Gene News and Research

New analysis links DNA variations to risks of specific breast cancer subtypes

An analysis of genetic studies covering 266,000 women has revealed 32 new sites on the human genome where variations in DNA appear to alter the risks of getting breast cancer.

18 May 2020

Researchers reveal the molecular biology behind Hyaline Fibromatosis Syndrome

Hyaline Fibromatosis Syndrome (HFS) is a rare but severe genetic disease that affects babies, children, and adults. Hyaline, a glassy substance, accumulates in the skin and various organs, and causes painful deformities that can lead to an early death.

18 May 2020

Novel microRNA biomarker could help detect lymph node metastases in pancreatic cancer patients

For years, surgeons have operated on pancreatic cancer patients to remove what they thought was a localized tumor only to discover that the disease had spread to other, inoperable parts of the body. Now, a City of Hope molecular scientist thinks he may have found a way to prevent ineffective surgeries and prolong the lives of these patients.

18 May 2020

Potential new treatment approach to fatal COVID-19

Researchers from the University of Colorado Anschutz Medical Campus and Pathways Bioscience in the United States have found that activating a transcription factor involved in oxidative stress regulation, antiviral activity, and inflammation may serve as a new treatment approach to coronavirus disease 2019 (COVID-19).

18 May 2020

Fibroblasts of different pancreatic diseases exhibit distinct properties, study reveals

Fibroblasts present in different pancreatic diseases are genetically distinct and their functions are 'programmed' by the unique environment of each disease, according to new research from the University of Liverpool (UK).

18 May 2020

Cigarette smoke spurs the lungs to make more SARS-CoV-2 receptors

New research from CSHL scientists suggests that cigarette smoke spurs the lungs to make more ACE2 (angiotensin-converting enzyme 2), the protein that the coronavirus responsible for COVID-19 grabs and uses to enter human cells.

18 May 2020

Neuroscientists discover anti-aging molecule that repairs age-related DNA damage

MIT neuroscientists have discovered that an enzyme called HDAC1 is critical for repairing age-related DNA damage to genes involved in memory and other cognitive functions.

18 May 2020

Host-virus interaction drives adaptive mutation in bat CoV related to SARS-CoVs

Virus and receptor diversity is shaped by the need to evolve advanced weaponry to facilitate virus entry and infection, on the one hand, and host resistance, on the other. A new paper published on the preprint server bioRxiv* shows how this mechanism operates in a bat coronavirus, which is related to the earlier SARS coronavirus.

17 May 2020

Study shows human monoclonal antibodies can effectively neutralize SARS-CoV-2

US researchers have published a proof of concept on the efficacy of human monoclonal antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in laboratory conditions, as well as their pioneering use in a mouse model. The study is available on the preprint server bioRxiv*.

17 May 2020

Study shows broad geographic and evolutionary dispersal of betacoronaviruses from African bats

A research group from Nigeria found evidence of long-distance transmission and dispersal between bat coronaviruses isolated in Africa and the ones Europe and Asia, as described in a new paper available on the preprint server bioRxiv.

17 May 2020

New algorithm could help investigate the genetic clues behind immunity

Scientists with UC San Diego's Jacobs School of Engineering and the Qualcomm Institute have developed a new gene prediction algorithm, called MINING-D, that could help researchers investigate the genetic clues behind the variation of symptoms shown in COVID-19 patients - information that is key to creating a versatile and effective vaccine.

15 May 2020

Genome-wide pattern found in glioblastoma tumors predicts patients' life expectancy

For the past 70 years, the best indicator of life expectancy for a patient with glioblastoma (GBM) -- the most common and the most aggressive brain cancer -- has simply been age at diagnosis.

15 May 2020

ChIP kits for high throughput antibody validation

Porvair Sciences report how its Chromatrap® ChIP kits provide an outstanding solution for antibodies suppliers looking to validate the performance of the antibodies they produce for chromatin immunoprecipitation (ChIP) assay kits.

From Porvair Sciences Limited 15 May 2020

Study shows the combined effect of inherited and acquired mutations on cancer development

The common belief that tumors arise via activation of a few genes that "drive" cancer development is unsupported by a widespread investigation into those genes and others in three large patient genetic databases, according to a study led by Yale Cancer Center researchers.

15 May 2020

Mouse model helps track organism’s development from embryonic stage to adulthood

Scientists at the Stem Cell Research program at Boston Children's Hospital and Dana-Farber Cancer Institute/Harvard Medical School have devised a mouse model that lets researchers track every cell in the body, from the embryonic stage until adulthood.

15 May 2020

Activity of malaria-causing parasite is driven by the parasite's own inherent clocks

The activity of the parasite that causes malaria is driven by the parasite's own inherent clock, new research led by UT Southwestern scientists suggests. The findings, published this week in Science, could lead to new ways to fight this pervasive and deadly disease.

15 May 2020

Precision medicine can determine the best drug treatment for severe heart disease

Is personalized medicine cost-effective? University of Alabama at Birmingham researcher Nita Limdi, Pharm.D., Ph.D., and colleagues across the United States have answered that question for one medical treatment.

15 May 2020

Genome-based monitoring of multi-resistant pathogen can help improve infection control

S. maltophilia strains occur in several natural and human associated ecosystems. The bacterium was long regarded as relatively unproblematic but is now considered to be one of the most feared hospital pathogens, as it frequently causes infections and is resistant to a number of antibiotics.

15 May 2020

Researchers study how brain cancer cells acquire resistance to radiation

In a vertical climb to avoid collision with a towering mountain, a plane ejects cargo to gain altitude. Investigators at the University of Minnesota showed that cancer cells perform similar feats in escaping the killing effects of radiation.

14 May 2020

Researchers identify new breast cancer gene in young women

Over the past 20 years, our knowledge of hereditary diseases has taken a quantum leap, and several hereditary gene variants have been found that may predispose to the development of cancer.

14 May 2020

Gene News and Research

Latest Gene News and Research

New analysis links DNA variations to risks of specific breast cancer subtypes

Researchers reveal the molecular biology behind Hyaline Fibromatosis Syndrome

Novel microRNA biomarker could help detect lymph node metastases in pancreatic cancer patients

Potential new treatment approach to fatal COVID-19

Fibroblasts of different pancreatic diseases exhibit distinct properties, study reveals

Cigarette smoke spurs the lungs to make more SARS-CoV-2 receptors

Neuroscientists discover anti-aging molecule that repairs age-related DNA damage

Host-virus interaction drives adaptive mutation in bat CoV related to SARS-CoVs

Study shows human monoclonal antibodies can effectively neutralize SARS-CoV-2

Study shows broad geographic and evolutionary dispersal of betacoronaviruses from African bats

New algorithm could help investigate the genetic clues behind immunity

Genome-wide pattern found in glioblastoma tumors predicts patients' life expectancy

ChIP kits for high throughput antibody validation

Study shows the combined effect of inherited and acquired mutations on cancer development

Mouse model helps track organism’s development from embryonic stage to adulthood

Activity of malaria-causing parasite is driven by the parasite's own inherent clocks

Precision medicine can determine the best drug treatment for severe heart disease

Genome-based monitoring of multi-resistant pathogen can help improve infection control

Researchers study how brain cancer cells acquire resistance to radiation

Researchers identify new breast cancer gene in young women

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