Gene News and Research

Latest Gene News and Research

ACMG: Technical standard on CFTR variant testing updated

It has been nearly two decades since the American College of Medical Genetics and Genomics, together with the American College of Obstetricians and Gynecologists, made the landmark recommendation that cystic fibrosis (CF) become the first target of pan-ethnic universal carrier screening, with ACMG identifying a core panel of 23 pathogenic variants to be tested.

14 May 2020

Using supercomputers to screen drugs for deadly heart arrhythmias

Death from sudden cardiac arrest makes headlines when it strikes athletes. But it also causes the most deaths by natural causes in the U.S. estimated at 325,000 per year.

14 May 2020

Researchers identify a group of dysregulated genes in autism

Autism has long been associated only with behavioral and environmental factors, but the role of genetics in its development is now increasingly evident. Some 100 genes have been found to play a role in autism spectrum disorder, and another thousand are being studied to the same end.

14 May 2020

A 'window of vulnerability' for re-infection with HIV after stem cell transplantation

Some people with HIV need to undergo an allogeneic stem cell transplantation in order to treat different types of blood cancer. Most of the patient's immune cells are eliminated during these transplantations.

14 May 2020

Rotavirus infection mainly affects children under 5 years of age

A research team from the University of Valencia has carried out a study of infection and immunity markers by detecting antibodies in the blood of 7 different genotypes of the rotavirus VP8 protein, the virus that causes infectious diarrhoea, and concludes that more frequent types mainly affect the child population.

14 May 2020

Study provides new insights on mechanisms that promote cancer

Like subway com muters on a crowded train, cells generally prefer not to be packed in too tightly. In fact, they have set up mechanisms to avoid this, a phenomenon called "contact inhibition." A hallmark of cancer cells is that they lack this contact inhibition, and instead become pushy, facilitating their spread.

14 May 2020

Variations in genome’s 'dark matter' region can make patients susceptible to inflammatory diseases

A study led by researchers at the Babraham Institute in collaboration with the Wellcome Sanger Institute has uncovered how variations in a non-protein coding 'dark matter' region of the genome could make patients susceptible to complex autoimmune and allergic diseases such as inflammatory bowel disease.

14 May 2020

Ori Biotech and CellGenix to collaborate in order to promote innovation within closed-system cell and gene therapy manufacturing

Ori Biotech Ltd announced a partnership to achieve closed-system preparation and the addition of CellGenix media and growth factors within CGT manufacturing.

14 May 2020

A deep look into hormone-producing cells of the gut

Researchers from the Hubrecht Institute and Utrecht University generated an in-depth description of the human hormone-producing cells of the gut, in a large collaborative effort with other research teams. The results are presented in the scientific journal Cell on the 13th of May.

13 May 2020

Research identifies a disease trigger for pancreatitis

One factor contributing to the development of pancreatitis lies in mutations within a cell membrane ion channel that is characterized by its specific permeability for calcium ions.

13 May 2020

Study shows why older individuals are vulnerable to COVID-19

A group of tiny RNA that should attack the virus causing COVID-19 when it tries to infect the body are diminished with age and chronic health problems, a decrease that likely helps explain why older individuals and those with preexisting medical conditions are vulnerable populations, investigators report.

13 May 2020

Researchers use “gene drive” technology to eliminate malaria mosquitoes in lab experiments

A modification that creates more male offspring was able to eliminate populations of malaria mosquitoes in lab experiments.

13 May 2020

Could JAK blockers help treat COVID-19?

A new study published in the journal Science Immunology in May 2020 reports that compounds that safely inhibit the JAK protein could be useful in treating COVID-19.

12 May 2020

A 'multi-omics' approach to the development of drugs against COVID-19

A new study published on the preprint server medRxiv* in May 2020 reports a multi-omics approach that could make it easier to develop drugs that are effective against COVID-19.

12 May 2020

Fasting-mimicking diet plus vitamin C could be effective at treating some cancer types

Scientists from USC and the IFOM Cancer Institute in Milan have found that a fasting-mimicking diet could be more effective at treating some types of cancer when combined with vitamin C.

12 May 2020

New discovery may contribute to early identification of aggressive breast tumors

Immune system cells in the blood of breast cancer patients undergo alterations early in the disease course, according to a study published in the journal Clinical & Translational Immunology.

12 May 2020

Potential for COVID-19 transmission from human eye

A new study published on the preprint server bioRxiv* in May 2020 reports the presence of ACE2 receptors in the eye at high concentrations. These molecules are the entry points for the SARS-CoV-2 virus that is causing the ongoing COVID-19 pandemic.

12 May 2020

Study shows how diarrhea-causing bug finds its way through the human gut

A study from UT Southwestern researchers sheds new light on how the bug that's the No. 1 cause of bacterial diarrhea finds its way through the human gut.

12 May 2020

Single-cell RNA-seq addresses key question in islet cell biology and diabetes research

The pancreas is an abdominal organ that produces digestive enzymes as well as hormones that regulate blood sugar levels. This hormone-producing function is localized to the islets of Langerhans, which constitute clusters of different endocrine cell types.

12 May 2020

Study provides genetic explanation behind the sex bias observed in certain diseases

Some diseases exhibit a clear sex bias, occurring more often, hitting harder or eliciting different symptoms in men or women.

12 May 2020

Gene News and Research

Latest Gene News and Research

ACMG: Technical standard on CFTR variant testing updated

Using supercomputers to screen drugs for deadly heart arrhythmias

Researchers identify a group of dysregulated genes in autism

A 'window of vulnerability' for re-infection with HIV after stem cell transplantation

Rotavirus infection mainly affects children under 5 years of age

Study provides new insights on mechanisms that promote cancer

Variations in genome’s 'dark matter' region can make patients susceptible to inflammatory diseases

Ori Biotech and CellGenix to collaborate in order to promote innovation within closed-system cell and gene therapy manufacturing

A deep look into hormone-producing cells of the gut

Research identifies a disease trigger for pancreatitis

Study shows why older individuals are vulnerable to COVID-19

Researchers use “gene drive” technology to eliminate malaria mosquitoes in lab experiments

Could JAK blockers help treat COVID-19?

A 'multi-omics' approach to the development of drugs against COVID-19

Fasting-mimicking diet plus vitamin C could be effective at treating some cancer types

New discovery may contribute to early identification of aggressive breast tumors

Potential for COVID-19 transmission from human eye

Study shows how diarrhea-causing bug finds its way through the human gut

Single-cell RNA-seq addresses key question in islet cell biology and diabetes research

Study provides genetic explanation behind the sex bias observed in certain diseases

eBook: Using iPSCs models for human disease research and drug discovery eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting