Gene News and Research

Latest Gene News and Research

Drug tolerant Tuberculosis could soon be tracked using genes

A team of researchers from the Rutgers New Jersey Medical School have found genetic foot prints of tuberculosis bacteria that are resistant to the commonly used anti-tubercular drugs. This could help scientists develop drugs to combat drug resistance in tuberculosis.

8 Sep 2019

Researchers discover role of GABA neurons in the central circadian clock

The research team led by Dr. Daisuke Ono and Prof. Akihiro Yamanaka of the Graduate School of Medicine, Nagoya University, collaborating with Prof. Ken-ichi Honma and Prof. Sato Honma of Hokkaido University Graduate School of Medicine, and Prof. Yuchio Yanagawa of Gunma University Graduate School of Medicine revealed that inhibitory neurons (GABAergic neurons) of the central circadian clock in the suprachiasmatic nucleus (SCN) refine circadian output rhythms.

8 Sep 2019

Age affects efficacy of immunotherapy treatment for breast cancer, preclinical study reveals

Recent clinical trials have indicated that immune checkpoint blockade (ICB) therapy, which is designed to unleash a patient's immune system to attack cancer, has been revolutionary in its implications for breast cancer treatment, especially for its potential to treat patients with triple negative breast cancer.

8 Sep 2019

UAB researchers identify biomarker for early beta cell death in Type 1 diabetes

Beta cells in the pancreas produce insulin. Their death is a key feature of Type 1 diabetes, and that loss starts long before diagnosis. However, there has been no straightforward way to measure that early loss.

8 Sep 2019

Researchers find synergistic connection between two deadly blood-clotting diseases

Two rare but potentially deadly blood-clotting diseases, namely thrombotic thrombocytopenic purpura, or TTP, and hemolytic uremic syndrome, or HUS, show similar pathologies -- a multitude of painful blockages in small blood vessels that cause varying degrees of organ injury throughout the body. However, the two disorders have distinct biological mechanisms.

8 Sep 2019

Serotonin and anti-depressants can have a major effect on the gut's microbiota

A new study in mice led by UCLA biologists strongly suggests that serotonin and drugs that target serotonin, such as anti-depressants, can have a major effect on the gut's microbiota -- the 100 trillion or so bacteria and other microbes that live in the human body's intestines.

6 Sep 2019

Small-cell clones in epithelial tissues organize differently than their normal-sized counterparts

Small-cell clones in proliferating epithelia – tissues that line all body surfaces – organize very differently than their normal-sized counterparts, according to a recent study from the Stowers Institute for Medical Research.

6 Sep 2019

Newly discovered resistance-spreading mechanism is independent of the use of antibiotics

Bacteria are becoming increasingly resistant to common antibiotics. Often, resistance is mediated by resistance genes, which can simply jump from one bacterial population to the next.

5 Sep 2019

How tuberculosis progresses: genetic factors play a major role

There are almost 1.8 billion people with tuberculosis bacilli in their body, but only about 5% to 15% develop overt infection, usually within 18 months of initial exposure. The reason behind this selective progression has been sought for decades by scientists from a variety of fields.

5 Sep 2019

Researchers receive $2.5 million NIH grant to study role of artemin in oral cancer pain

Researchers at New York University Oral Cancer Center were awarded a $2.5 million grant (R01CA228525) from the National Cancer Institute, part of the National Institutes of Health, to study the role of artemin in oral cancer pain and growth.

5 Sep 2019

Researchers discover a molecule that regulates tumor development in different types of cancers

Researchers from the Josep Carreras Leukemia Research Institute, discover that a non-coding region of the genome originates a key molecule for the proliferation of tumors in breast cancer and some types of sarcoma.

5 Sep 2019

Large-scale study maps the genetic underpinnings of early TB progression

While the vast majority of the 1.8 billion people infected with the TB bacterium never experience active disease, an estimated 5 to 15 percent do develop full-blown infections--roughly half of them within 18 months of exposure.

4 Sep 2019

Resuscitation from hemorrhagic shock via transfusion of anaerobically stored RBCs improves outcomes

Transfusion of red blood cells (RBCs) stored anaerobically – in the absence of oxygen – is a promising technique to improve resuscitation from hemorrhagic shock, according to animal studies reported in SHOCK: Injury, Inflammation, and Sepsis: Laboratory and Clinical Approaches, Official Journal of the Shock Society.

4 Sep 2019

Study aims to achieve earlier diagnosis of ATTR cardiac amyloidosis in minority populations

Researchers at Boston Medical Center and Boston University School of Medicine, in collaboration with Columbia University Irving Medical Center, are leading a national, multi-site study aimed to achieve earlier diagnosis of transthyretin cardiac amyloidosis.

4 Sep 2019

Scientists find receptor protein in the brain that promotes stress resilience

Scientists have discovered that a receptor on the surface of brain cells plays a key role in regulating how both animals and people respond to stress.

4 Sep 2019

Researchers develop new technique for rapid breakdown of cellular proteins

Cellular functions depend on the functionality of proteins, and these functions are disturbed in diseases. A core aim of cell biological research is to determine the functions of individual proteins and how their disturbances result in disease.

4 Sep 2019

Neurobiological pathophysiology of schizophrenia differs based on gender

The neurobiological pathophysiology of schizophrenia differs significantly between males and females, according to a new study.

4 Sep 2019

Melatonin promises to help reduce bone loss in space flight

New research suggests that the problem of bone loss caused by microgravity conditions in space flight may be successfully treated using the time-tested drug melatonin. Melatonin increases the level of calcitonin in bone, which suppresses the bone-destroying activity of osteoclastic cells and helps maintain bone density.

4 Sep 2019

Breast cancer gene could be key to developing targeted therapy for hepatoblastoma

Hepatoblastoma is a rare form of liver cancer affecting just a few individuals per million. However, it is the leading cause of liver cancer in infants and young children, with most patients diagnosed before their third birthday.

4 Sep 2019

Artificial intelligence learns complex patterns between genes and diseases

Artificial intelligence is being harnessed by researchers to track down genes that cause disease. A KAUST team is taking a creative, combined deep learning approach that uses data from multiple sources to teach algorithms how to find patterns between genes and diseases.

4 Sep 2019

Gene News and Research

Latest Gene News and Research

Drug tolerant Tuberculosis could soon be tracked using genes

Researchers discover role of GABA neurons in the central circadian clock

Age affects efficacy of immunotherapy treatment for breast cancer, preclinical study reveals

UAB researchers identify biomarker for early beta cell death in Type 1 diabetes

Researchers find synergistic connection between two deadly blood-clotting diseases

Serotonin and anti-depressants can have a major effect on the gut's microbiota

Small-cell clones in epithelial tissues organize differently than their normal-sized counterparts

Newly discovered resistance-spreading mechanism is independent of the use of antibiotics

How tuberculosis progresses: genetic factors play a major role

Researchers receive $2.5 million NIH grant to study role of artemin in oral cancer pain

Researchers discover a molecule that regulates tumor development in different types of cancers

Large-scale study maps the genetic underpinnings of early TB progression

Resuscitation from hemorrhagic shock via transfusion of anaerobically stored RBCs improves outcomes

Study aims to achieve earlier diagnosis of ATTR cardiac amyloidosis in minority populations

Scientists find receptor protein in the brain that promotes stress resilience

Researchers develop new technique for rapid breakdown of cellular proteins

Neurobiological pathophysiology of schizophrenia differs based on gender

Melatonin promises to help reduce bone loss in space flight

Breast cancer gene could be key to developing targeted therapy for hepatoblastoma

Artificial intelligence learns complex patterns between genes and diseases

eBook: Using iPSCs models for human disease research and drug discovery eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

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