Gene News and Research

Latest Gene News and Research

Mount Sinai awarded more than $10 million in federal funding for research on glioblastoma

The Department of Neurosurgery at the Icahn School of Medicine at Mount Sinai has received more than $10 million in federal funding for several projects focusing on brain tumor research.

2 Jan 2020

Study reveals key insight into the development of hair bundles

New research reveals a key insight into the development of hair bundles, the intricately complex assemblies in the inner ear responsible for hearing.

2 Jan 2020

Researchers discover how c-Cbl protein modulates tumor growth

Immune checkpoints are surface proteins that cancer cells use to evade immune response. These surface proteins are critical for cancer cell growth and drugs targeting these proteins have revolutionized the management of patients with a wide array of cancers.

2 Jan 2020

Promega and MilliporeSigma sign license agreement to expand the potential of CRISPR

Promega announce license agreement with MilliporeSigma, a leader in genome editing, to access MilliporeSigma’s foundational CRISPR genome-editing technology.

From Promega Corporation 2 Jan 2020

Advancement in reconstitution of the blood system from human pluripotent stem cells

The reconstitution of the blood system in humans holds great therapeutic potential to treat many disorders, like blood cancers, sickle-cell anemia and others.

31 Dec 2019

New dementia vaccine may proceed to clinical trials after successful testing

A preventive treatment for dementia may proceed to clinical trials after successful animal testing.

31 Dec 2019

Grizzly bears' strategy could help prevent muscle atrophy in humans

Grizzly bears spend many months in hibernation, but their muscles do not suffer from the lack of movement. In the journal "Scientific Reports", a team led by Michael Gotthardt reports on how they manage to do this.

30 Dec 2019

Study provides better understanding of mechanisms that limit cilia number in cells

One of the wonders of cell biology is its symmetry. Mammalian cells have one nucleus and one cell membrane, and most humans have 23 pairs of chromosomes.

30 Dec 2019

Scientists discover potential drug compounds that target common type of liver cancer

Scientists from the Cancer Science Institute of Singapore at the National University of Singapore, and the Agency for Science, Technology and Research (A*STAR)'s Genome Institute of Singapore have discovered four potential drug compounds that target hepatocellular carcinoma, the most common type of liver cancer.

30 Dec 2019

Study uncovers key protein that supports the growth of many colorectal cancers

Researchers at the University of Toronto have identified a key protein that supports the growth of many colorectal cancers.

28 Dec 2019

Study reveals rapid effects of diet on sperm quality

Sperm are influenced by diet, and the effects arise rapidly. This is the conclusion of a study by researchers at Linköping University, in which healthy young men were fed a diet rich in sugar.

28 Dec 2019

Lab-grown brain organoids may hold the answers to personalized treatments for glioblastomas

Lab-grown brain organoids developed from a patient's own glioblastoma, the most aggressive and common form of brain cancer, may hold the answers on how to best treat it.

26 Dec 2019

Researchers identify new insecticide resistance mechanism by mosquitoes

Researchers at LSTM have identified a completely new mechanism by which mosquitoes that carry malaria are becoming resistant to insecticide.

26 Dec 2019

CD4 T cells are not to be blamed for pushing dengue fever from bad to worse

No one knows what makes a mild dengue viral infection morph into a severe and sometimes deadly dengue hemorrhagic fever/dengue shock syndrome.

26 Dec 2019

New spatiomolecular map may advance understanding of the brain's decision-making area

Researchers at Karolinska Institutet have come one step closer toward understanding how the part of our brain that is central for decision-making and the development of addiction is organized on a molecular level.

26 Dec 2019

Synthetic mRNA nanoparticles restore tumor suppressor gene, make cancer cells susceptible to drugs

In preclinical experiments, investigators restored p53 using synthetic mRNA nanoparticles, making lung and liver cancer cells susceptible to available cancer drugs.

23 Dec 2019

Inserting end-modified DNA fragments with CRISPR-Cas9 yields highest efficiency

University of Illinois researchers achieved the highest reported rates of inserting genes into human cells with the CRISPR-Cas9 gene-editing system, a necessary step for harnessing CRISPR for clinical gene-therapy applications.

23 Dec 2019

Ancestral-sequence reconstruction of FMO genes unveils structure of important enzyme

To disarm toxic substances, many organisms - including humans - possess enzymes called flavin-containing monooxygenases. Despite their importance, the structure of the enzymes has not been resolved, as the protein is too unstable to study in detail.

23 Dec 2019

Research findings may one day help keep ALS at bay

A new study published in the journal Nature Medicine on December 23, 2019, shows how to silence a defective gene responsible for the degeneration of the motor neurons in Lou Gehrig’s disease, or amyotrophic lateral sclerosis (ALS), in adult mice. This could help prevent disease progression if the condition is already symptomatic, and even suppress the illness if it has not yet started.

23 Dec 2019

Immunosupressant combination therapy for glioblastoma shows promise

Researchers from the University of Texas have found an immunosuppressing target for the treatment of glioblastoma. In mice studies the team has identified CD73 macrophages which could be used to treat the cancers. The team also performed studies on human tumours to arrive at their conclusions. The study was published in the latest issue of the journal Nature Medicine this week.

23 Dec 2019

Gene News and Research

Latest Gene News and Research

Mount Sinai awarded more than $10 million in federal funding for research on glioblastoma

Study reveals key insight into the development of hair bundles

Researchers discover how c-Cbl protein modulates tumor growth

Promega and MilliporeSigma sign license agreement to expand the potential of CRISPR

Advancement in reconstitution of the blood system from human pluripotent stem cells

New dementia vaccine may proceed to clinical trials after successful testing

Grizzly bears' strategy could help prevent muscle atrophy in humans

Study provides better understanding of mechanisms that limit cilia number in cells

Scientists discover potential drug compounds that target common type of liver cancer

Study uncovers key protein that supports the growth of many colorectal cancers

Study reveals rapid effects of diet on sperm quality

Lab-grown brain organoids may hold the answers to personalized treatments for glioblastomas

Researchers identify new insecticide resistance mechanism by mosquitoes

CD4 T cells are not to be blamed for pushing dengue fever from bad to worse

New spatiomolecular map may advance understanding of the brain's decision-making area

Synthetic mRNA nanoparticles restore tumor suppressor gene, make cancer cells susceptible to drugs

Inserting end-modified DNA fragments with CRISPR-Cas9 yields highest efficiency

Ancestral-sequence reconstruction of FMO genes unveils structure of important enzyme

Research findings may one day help keep ALS at bay

Immunosupressant combination therapy for glioblastoma shows promise

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research