Gene News and Research

Latest Gene News and Research

Conformance of genetic characteristics found to be crucial for longer preservation of kidney graft

The conformance of genetic characteristics is essential for the long-term function after kidney transplantation. This is the central result of a recent study in the top journal “The Lancet” with more than 500 patients after kidney transplantation, conducted by a global consortium led by Rainer Oberbauer and his colleagues Roman Reindl-Schwaighofer and Andreas Heinzel from the Division of Nephrology and Dialysis at MedUni Vienna.

15 Feb 2019

UVA scientists find potential explanation for mysterious cell death in Alzheimer’s, Parkinson’s

Scientists at the University of Virginia School of Medicine have identified a potential explanation for the mysterious death of specific brain cells seen in Alzheimer’s, Parkinson’s and other neurodegenerative diseases.

15 Feb 2019

Scientists implicate hidden genes in the severity of autism symptoms

Scientists at the University of Colorado Anschutz Medical Campus have implicated a largely hidden part of the human genome in the severity of autism symptoms, a discovery that could lead to new insights into the disorder and eventually to clinical therapies for the condition.

15 Feb 2019

New method for improved visualization of single-cell RNA- sequencing data

Like going from a pinhole camera to a Polaroid, a significant mathematical update to the formula for a popular bioinformatics data visualization method will allow researchers to develop snapshots of single-cell gene expression not only several times faster but also at much higher-resolution.

15 Feb 2019

Discovery of weakness in a rare cancer could be exploited with drugs

Cancer cells are, in some respects, impressive: They can grow relentlessly, sidestep the aging process by becoming immortal, and evade the immune system's persistent attacks. But in the process of acquiring such superpowers, the cells must occasionally relinquish other, more mundane skills--including the ability to produce certain nutrients.

15 Feb 2019

New study seeks to understand how colibactin causes cancer

For more than a decade, scientists have worked to understand the connection between colibactin, a compound produced by certain strains of E. coli, and colorectal cancer, but have been hampered by their inability to isolate the compound.

15 Feb 2019

Researchers study animal venoms to identify new medicines for treating diseases

Animal venoms are the subject of study at research center based at the Butantan Institute in São Paulo. But in this case, the idea is not to find antidotes, but rather to use the properties of the venoms themselves to identify molecular targets of diseases and, armed with that knowledge, develop new compounds that can be used as medicines.

15 Feb 2019

Genetic variations in a fourth gene associated with higher ALL risk in Hispanic children

St. Jude Children's Research Hospital scientists have identified genetic variations in a fourth gene that are associated with an increased risk of acute lymphoblastic leukemia in Hispanic children. The research appears today in the journal Blood.

15 Feb 2019

Human cells can change their original function to battle against diabetes

For the first time, researchers have shown that ordinary human cells can change their original function. This may give new hope for diabetes patients.

14 Feb 2019

Blood-based liquid biopsies can accurately track cancer treatment responses

Results of two clinical studies have added to evidence that blood-based liquid biopsies can accurately track lung cancer treatment responses by measuring circulating tumor DNA (ctDNA) during immunotherapy and related treatments.

14 Feb 2019

Study shows how neuroactive steroids inhibit activity of pro-inflammatory proteins

For the first time, scientists discovered how neuroactive steroids naturally found in the brain and bloodstream inhibit the activity of a specific kind of protein called Toll-like receptors, which have been known to play a role in inflammation in many organs, including the brain.

14 Feb 2019

Researchers comprehensively sequence the human immune system

For the first time ever, researchers are comprehensively sequencing the human immune system, which is billions of times larger than the human genome. In a new study published in Nature from the Human Vaccines Project, scientists have sequenced a key part of this vast and mysterious system -- the genes encoding the circulating B cell receptor repertoire.

14 Feb 2019

Study identifies protein regulator that induces Th17 cells to cause multiple sclerosis

Inflammatory and autoimmune diseases such as psoriasis, rheumatoid arthritis, and multiple sclerosis (MS) are a major healthcare burden worldwide and are life-altering conditions for afflicted patients.

14 Feb 2019

Novel approach uses small amounts of tissue to quantify PD-L1 expression levels in tumors

Immune checkpoint inhibitors, such as the anti-PD-1 antibody pembrolizumab, have become important tools for managing non-small-cell lung cancer.

14 Feb 2019

Movement impairments in autism can be reversed through behavioral training

Researchers from Cardiff University have established a link between a genetic mutation and developmental movement impairments in autism.

13 Feb 2019

Study discovers new therapy for aggressive blood cancer

Acute myeloid leukemia is the most common form of acute leukemia. It is characterized by an increase of malignant myeloid progenitor cells at the expense of mature blood cells.

13 Feb 2019

Increased activity of EHMT2 gene deficient neurons could cause autism in humans

A novel investigation into the impacts of neuronal mutations on autism-related characteristics in humans has been described in the open-access journal eLife.

13 Feb 2019

New study provides insights into developmental organization of the brain

What makes us human, and where does this mysterious property of "humanness" come from? Humans are genetically similar to chimpanzees and bonobos, yet there exist obvious behavioral and cognitive differences.

13 Feb 2019

New process efficiently reprograms stem cells in one step using measles virus vector

Induced pluripotent stem cells, the workhorse of many regenerative medicine projects, start out as differentiated cells that are reprogrammed to pluripotent stem cells by exposure to a complex set of genetic cocktails.

13 Feb 2019

Microbiologists identify enzyme that makes Helicobacter so adaptable

The bacterial pathogen Helicobacter pylori owes its worldwide distribution to its genetic adaptability. Ludwig-Maximilians-Universitaet Munich microbiologists have identified an enzyme that plays a vital role in the flexible control of global gene expression in the species.

13 Feb 2019

Gene News and Research

Latest Gene News and Research

Conformance of genetic characteristics found to be crucial for longer preservation of kidney graft

UVA scientists find potential explanation for mysterious cell death in Alzheimer’s, Parkinson’s

Scientists implicate hidden genes in the severity of autism symptoms

New method for improved visualization of single-cell RNA- sequencing data

Discovery of weakness in a rare cancer could be exploited with drugs

New study seeks to understand how colibactin causes cancer

Researchers study animal venoms to identify new medicines for treating diseases

Genetic variations in a fourth gene associated with higher ALL risk in Hispanic children

Human cells can change their original function to battle against diabetes

Blood-based liquid biopsies can accurately track cancer treatment responses

Study shows how neuroactive steroids inhibit activity of pro-inflammatory proteins

Researchers comprehensively sequence the human immune system

Study identifies protein regulator that induces Th17 cells to cause multiple sclerosis

Novel approach uses small amounts of tissue to quantify PD-L1 expression levels in tumors

Movement impairments in autism can be reversed through behavioral training

Study discovers new therapy for aggressive blood cancer

Increased activity of EHMT2 gene deficient neurons could cause autism in humans

New study provides insights into developmental organization of the brain

New process efficiently reprograms stem cells in one step using measles virus vector

Microbiologists identify enzyme that makes Helicobacter so adaptable

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