Gene News and Research

Latest Gene News and Research

Mutations linked with sensitivity or resistance to immunotherapy in mNSCLC

The relationship between gene alterations and response to anti-PD-L1 with and without anti-CTLA-4 are not well characterized.

10 Sep 2019

Salk researchers develop method to reveal epigenetic features of brain cells

The brain's prefrontal cortex, which gives us our ability to solve problems and plan ahead, contains billions of cells. But understanding the large diversity of cell types in this critical region, each with unique genetic and molecular properties, has been challenging.

10 Sep 2019

Lung-MAP study: Majority of cancer patients don't understand genomic test results

A majority of cancer patients don't understand key aspects of the genomic test results they receive as participants in biomarker-driven clinical trials, according to a first-of-its-kind pilot study conducted under the Lung Cancer Master Protocol.

10 Sep 2019

Fatty food changes the brain to affect homeostasis and metabolism

While we all know that eating fatty food pushes up our body weight, a new study now shows it also affects the way the brain keeps track of and corrects all metabolic irregularities in the body. Soon after tucking into a high-fat, high-carb meal – as soon as three days later – the hypothalamus shows inflammation.

10 Sep 2019

Brain networks develop differently in boys and girls at puberty, research shows

Scientists have found that brain networks develop differently in males and females at puberty, with boys showing an increase in connectivity in certain brain areas, and girls showing a decrease in connectivity as puberty progresses.

9 Sep 2019

Researchers develop new cocktail of drugs that shrink pancreatic tumors

Cancer is relentless and resilient. When a drug blocks a cancer cell's main survival pathway, the cell avoids the obstacle by taking different pathways or detours to save itself. This tactic is called "developing resistance," and it's one of the key challenges researchers face when seeking effective therapeutics to combat pancreatic ductal adenocarcinoma (PDA).

9 Sep 2019

Hemophilia much more prevalent than previously thought

More than 1,125,000 men around the world have the inherited bleeding disorder of hemophilia, and 418,000 of those have a severe version of the mostly undiagnosed disease, says a new study led by McMaster University researchers.

9 Sep 2019

Eradicating malaria by 2050 would be 'an achievement of historic proportions', say experts

According to a major report by 41 leading scientists, health-policy experts and economists, the world could be free of malaria by 2050.

9 Sep 2019

Rutgers study finds genetically tractable cause of drug-tolerant tuberculosis

A Rutgers New Jersey Medical School study has found a genetically tractable cause of drug tolerant tuberculosis, paving the way for researchers to develop new drugs to combat the global TB epidemic and cure the disease.

9 Sep 2019

Drug tolerant Tuberculosis could soon be tracked using genes

A team of researchers from the Rutgers New Jersey Medical School have found genetic foot prints of tuberculosis bacteria that are resistant to the commonly used anti-tubercular drugs. This could help scientists develop drugs to combat drug resistance in tuberculosis.

8 Sep 2019

Researchers discover role of GABA neurons in the central circadian clock

The research team led by Dr. Daisuke Ono and Prof. Akihiro Yamanaka of the Graduate School of Medicine, Nagoya University, collaborating with Prof. Ken-ichi Honma and Prof. Sato Honma of Hokkaido University Graduate School of Medicine, and Prof. Yuchio Yanagawa of Gunma University Graduate School of Medicine revealed that inhibitory neurons (GABAergic neurons) of the central circadian clock in the suprachiasmatic nucleus (SCN) refine circadian output rhythms.

8 Sep 2019

Age affects efficacy of immunotherapy treatment for breast cancer, preclinical study reveals

Recent clinical trials have indicated that immune checkpoint blockade (ICB) therapy, which is designed to unleash a patient's immune system to attack cancer, has been revolutionary in its implications for breast cancer treatment, especially for its potential to treat patients with triple negative breast cancer.

8 Sep 2019

UAB researchers identify biomarker for early beta cell death in Type 1 diabetes

Beta cells in the pancreas produce insulin. Their death is a key feature of Type 1 diabetes, and that loss starts long before diagnosis. However, there has been no straightforward way to measure that early loss.

8 Sep 2019

Researchers find synergistic connection between two deadly blood-clotting diseases

Two rare but potentially deadly blood-clotting diseases, namely thrombotic thrombocytopenic purpura, or TTP, and hemolytic uremic syndrome, or HUS, show similar pathologies -- a multitude of painful blockages in small blood vessels that cause varying degrees of organ injury throughout the body. However, the two disorders have distinct biological mechanisms.

8 Sep 2019

Serotonin and anti-depressants can have a major effect on the gut's microbiota

A new study in mice led by UCLA biologists strongly suggests that serotonin and drugs that target serotonin, such as anti-depressants, can have a major effect on the gut's microbiota -- the 100 trillion or so bacteria and other microbes that live in the human body's intestines.

6 Sep 2019

Small-cell clones in epithelial tissues organize differently than their normal-sized counterparts

Small-cell clones in proliferating epithelia – tissues that line all body surfaces – organize very differently than their normal-sized counterparts, according to a recent study from the Stowers Institute for Medical Research.

6 Sep 2019

Newly discovered resistance-spreading mechanism is independent of the use of antibiotics

Bacteria are becoming increasingly resistant to common antibiotics. Often, resistance is mediated by resistance genes, which can simply jump from one bacterial population to the next.

5 Sep 2019

How tuberculosis progresses: genetic factors play a major role

There are almost 1.8 billion people with tuberculosis bacilli in their body, but only about 5% to 15% develop overt infection, usually within 18 months of initial exposure. The reason behind this selective progression has been sought for decades by scientists from a variety of fields.

5 Sep 2019

Researchers receive $2.5 million NIH grant to study role of artemin in oral cancer pain

Researchers at New York University Oral Cancer Center were awarded a $2.5 million grant (R01CA228525) from the National Cancer Institute, part of the National Institutes of Health, to study the role of artemin in oral cancer pain and growth.

5 Sep 2019

Researchers discover a molecule that regulates tumor development in different types of cancers

Researchers from the Josep Carreras Leukemia Research Institute, discover that a non-coding region of the genome originates a key molecule for the proliferation of tumors in breast cancer and some types of sarcoma.

5 Sep 2019

Gene News and Research

Latest Gene News and Research

Mutations linked with sensitivity or resistance to immunotherapy in mNSCLC

Salk researchers develop method to reveal epigenetic features of brain cells

Lung-MAP study: Majority of cancer patients don't understand genomic test results

Fatty food changes the brain to affect homeostasis and metabolism

Brain networks develop differently in boys and girls at puberty, research shows

Researchers develop new cocktail of drugs that shrink pancreatic tumors

Hemophilia much more prevalent than previously thought

Eradicating malaria by 2050 would be 'an achievement of historic proportions', say experts

Rutgers study finds genetically tractable cause of drug-tolerant tuberculosis

Drug tolerant Tuberculosis could soon be tracked using genes

Researchers discover role of GABA neurons in the central circadian clock

Age affects efficacy of immunotherapy treatment for breast cancer, preclinical study reveals

UAB researchers identify biomarker for early beta cell death in Type 1 diabetes

Researchers find synergistic connection between two deadly blood-clotting diseases

Serotonin and anti-depressants can have a major effect on the gut's microbiota

Small-cell clones in epithelial tissues organize differently than their normal-sized counterparts

Newly discovered resistance-spreading mechanism is independent of the use of antibiotics

How tuberculosis progresses: genetic factors play a major role

Researchers receive $2.5 million NIH grant to study role of artemin in oral cancer pain

Researchers discover a molecule that regulates tumor development in different types of cancers

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

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Innovating Texture and Culture in Plant-Based Foods

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