Gene News and Research

Latest Gene News and Research

New $400 million donation reinforces Columbia's leadership in biomedical science

Columbia University announced today a new $400 million gift from Roy and Diana Vagelos, which will secure Columbia's leadership in biomedical science research and education and produce a vast array of compelling opportunities for improving society's health and wellbeing.

22 Aug 2024

Study shows frequent mitochondrial DNA insertion in the brain cells

As direct descendants of ancient bacteria, mitochondria have always been a little alien.

22 Aug 2024

New technique speeds up screening of DNA molecules

Studying how single DNA molecules behave helps us to better understand genetic disorders and design better drugs.

22 Aug 2024

Study reveals RAD51D variant enrichment in Chinese ovarian cancer patients

Researchers from BGI Genomics and Fudan University published new findings on OV among Chinese patients in JCO Global Oncology.

22 Aug 2024

Robotic gait training improves mobility in patients with spinal and bulbar muscular atrophy

Spinal and bulbar muscular atrophy (SBMA) is a rare X-linked neuromuscular disorder that results from an abnormal expansion of gene sequences in the androgen receptor gene.

22 Aug 2024

Research shows predation drives evolution of virulence in bacteria

Opportunistic pathogens are typically benign microbes that can sometimes cause infections in individuals with weakened immune systems or when they gain access to sterile areas of the body.

22 Aug 2024

Research unveils how HMGA2 regulates stress responses in stem cells

Kumamoto University researchers have made a groundbreaking discovery that sheds light on how the HMGA2 gene - an essential transcriptional activator involved in chromatin modification - regulates stress responses in hematopoietic stem cells (HSCs), thereby enhancing blood cell production recovery.

22 Aug 2024

Study reveals how macrophages affect cardiac fibroblast fate post-myocardial infarction

The research uncovers a previously unappreciated mechanism by which macrophages influence the fate of CFs post-MI.

22 Aug 2024

New tool could revolutionize cardiovascular risk management: PRESS score validated

The association between platelet hyperreactivity and the risk of cardiovascular events.

22 Aug 2024

Common fatty acid could improve treatment of recurrent bacterial vaginosis infections

Researchers investigated oleic acid as a potential treatment to inhibit Lactobacillus iners dominance in bacterial vaginosis.

22 Aug 2024

Study links fine particulate matter exposure to increased risk of gestational diabetes

Researchers assesses the relationship between exposure to fine particulate matter and the risk of gestational diabetes mellitus.

22 Aug 2024

DNA scavengers break down antibiotic-resistant genes

For nearly a century, scientists have waged war on antibiotic-resistant microbes. Michigan State University researchers say they've found a new way to prevent it – by unleashing "DNA scavengers" in wastewater treatment plants.

22 Aug 2024

mRNA therapy shows promise for maple syrup urine disease

Researchers from the University of Pennsylvania, Perelman School of Medicine, Gene Therapy Program, and Moderna, have shown that repeated administration of lipid nanoparticle-encapsulated mRNA therapy significantly extended survival and reduced serum leucine levels in a mouse model of maple syrup urine disease (MSUD).

22 Aug 2024

The critical role of PGK1 in Parkinson's disease

An enzyme called PGK1 has an unexpectedly critical role in the production of chemical energy in brain cells, according to a preclinical study led by researchers at Weill Cornell Medicine. The investigators found that boosting its activity may help the brain resist the energy deficits that can lead to Parkinson's disease.

21 Aug 2024

New discovery reveals how DNA regulates inheritance of disease mutations

University of Queensland researchers have discovered a mechanism in DNA that regulates how disease-causing mutations are inherited.

21 Aug 2024

Protein encoded by the ASPN gene plays a protective role in pulmonary arterial hypertension

A new study from researchers with UCLA Health and collaborating organizations has found that asporin, a protein encoded by the ASPN gene, plays a protective role in pulmonary arterial hypertension (PAH).

21 Aug 2024

Targeted therapy slows endometrial cancer growth in mice models

There may be a way to slow the growth of endometrial cancer through targeted cancer cell therapy, according to new research from the University of Missouri School of Medicine.

21 Aug 2024

The role of the gut microbiota in multiple sclerosis: A scientometric analysis reveals key research trends

Researchers examine the relationship between gut microbiota and multiple sclerosis.

21 Aug 2024

Study finds potential for antidiabetic drugs to modify osteoarthritis risk

Whether antidiabetic medications could potentially be used as disease-modifying osteoarthritis drugs or DMOADs for the therapeutic management of osteoarthritis.

21 Aug 2024

Spatial transcriptomics unlocks malaria's liver stage secrets

For the malaria parasite to reach the blood of its human host, it must first enter the liver, where only a small number of parasites differentiate and replicate for upwards of seven days, making it a bottleneck in the parasite's lifecycle. This bottleneck makes the liver stage an optimal target for effective and long-lasting vaccines against the disease. Using Spatial Transcriptomics and single-cell RNA-sequencing technologies, researchers at Stockholm University have for the first time managed to create a spatio-temporal map of malaria infection in the mouse liver. A study that was recently published in Nature Communications.

21 Aug 2024

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Gene News and Research

Latest Gene News and Research

New $400 million donation reinforces Columbia's leadership in biomedical science

Study shows frequent mitochondrial DNA insertion in the brain cells

New technique speeds up screening of DNA molecules

Study reveals RAD51D variant enrichment in Chinese ovarian cancer patients

Robotic gait training improves mobility in patients with spinal and bulbar muscular atrophy

Research shows predation drives evolution of virulence in bacteria

Research unveils how HMGA2 regulates stress responses in stem cells

Study reveals how macrophages affect cardiac fibroblast fate post-myocardial infarction

New tool could revolutionize cardiovascular risk management: PRESS score validated

Common fatty acid could improve treatment of recurrent bacterial vaginosis infections

Study links fine particulate matter exposure to increased risk of gestational diabetes

DNA scavengers break down antibiotic-resistant genes

mRNA therapy shows promise for maple syrup urine disease

The critical role of PGK1 in Parkinson's disease

New discovery reveals how DNA regulates inheritance of disease mutations

Protein encoded by the ASPN gene plays a protective role in pulmonary arterial hypertension

Targeted therapy slows endometrial cancer growth in mice models

The role of the gut microbiota in multiple sclerosis: A scientometric analysis reveals key research trends

Study finds potential for antidiabetic drugs to modify osteoarthritis risk

Spatial transcriptomics unlocks malaria's liver stage secrets

eBook: Using iPSCs models for human disease research and drug discovery eBook

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering