Gene News and Research

Latest Gene News and Research

Rare genetic mutation tied to increased risk of tuberculosis

Tuberculosis is a confounding scourge. It's the leading cause of death from infectious disease in the world, and yet it's estimated that those deaths represent perhaps 5% of infections with Mycobacterium tuberculosis (Mtb).

30 Aug 2024

Vutrisiran shows potential to become the new standard of care for rare heart disease

Vutrisiran significantly improved mortality, cardiovascular events and markers of disease progression in patients with transthyretin amyloidosis with cardiomyopathy (ATTR-CM), according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

30 Aug 2024

AI tool RENAISSANCE transforms creation of kinetic models in cellular metabolism

Understanding how cells process nutrients and produce energy - collectively known as metabolism - is essential in biology. However, analyzing the vast amounts of data on cellular processes to determine metabolic states is a complex task.

30 Aug 2024

New consensus on assessing carcinogenic risks of gene therapies

A new article in the peer-reviewed journal Human Gene Therapy describes the consensus reached by invited experts who participated in a meeting to evaluate the potential carcinogenicity of gene therapies.

30 Aug 2024

Redefining 5hmC: More than just a stepping stone in the DNA demethylation pathway

An important DNA modification is methylation, or the addition of a methyl group to the 5th carbon of cytosine. This forms 5-methylcytosine (5mC), typically associated with repression of gene expression.

From biomodal 30 Aug 2024

CBL identified as the most promising potential biomarker for aortic dissection

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Aortic dissection (AD) is a fatal cardiovascular disease for which the key involved genes are largely unknown.

29 Aug 2024

Vancomycin resistance in Staphylococcus aureus may become more stable over time

Staphylococcus aureus has the potential to develop durable vancomycin resistance, according to a study published August 28, 2024, in the open-access journal PLOS Pathogens by Samuel Blechman and Erik Wright from the University of Pittsburgh, USA.

29 Aug 2024

Discovery of borderzone inflammation offers new avenues for heart failure prevention

Ischemic heart disease is the most common cause of death in the world. It begins with a "heart attack", also known as a myocardial infarction (MI), which causes part of the heart to die due to inadequate coronary blood flow.

29 Aug 2024

New bacterial defense mechanism revealed as potential tool for genome editing

Scientists who have described in a new study the step-by-step details of a bacterial defense strategy see the mechanism as a promising platform for development of a new genome-editing method.

29 Aug 2024

Study reveals key role of A20 protein in controlling inflammation in liver disease

Many individuals worldwide suffer from chronic liver disease (CLD), which poses significant concerns for its tendency to lead to hepatocellular carcinoma or liver failure. CLD is characterized by inflammation and fibrosis.

29 Aug 2024

Mapping DNA’s hidden knot-like structures may revolutionize disease treatment

Innovative study of DNA's hidden structures may open up new approaches for treatment and diagnosis of diseases, including cancer.

29 Aug 2024

AI unveils secrets of protein stability

Researchers at the Center for Algorithmic and Robotized Synthesis within the Institute for Basic Science have taken a significant step forward in understanding the stability of proteins by leveraging the power of AI. The research team used AlphaFold2 to explore how mutations affect protein stability - a crucial factor in ensuring proteins function correctly and do not cause diseases like Alzheimer's.

29 Aug 2024

New system can spot genetic markers of autism in brain images with high accuracy

A multi-university research team co-led by University of Virginia engineering professor Gustavo K. Rohde has developed a system that can spot genetic markers of autism in brain images with 89 to 95% accuracy.

28 Aug 2024

Study reveals a new target for universal treatment for autoimmune diseases

More than two decades ago, a research team in the lab of David Hafler, a Yale researcher who at the time was at Harvard, discovered a type of T cell in humans that suppresses the immune system; they later found that these so-called regulatory T cells, when defective, are an underlying cause of autoimmune disease, specifically multiple sclerosis (MS).

28 Aug 2024

Study reveals how bacteria pass on traits without DNA changes

Bacterial cells can "remember" brief, temporary changes to their bodies and immediate surroundings, a new Northwestern University and University of Texas-Southwestern study has found.

28 Aug 2024

16 promising postdoctoral scientists awarded Damon Runyon Fellowships for cancer research

The Damon Runyon Cancer Research Foundation has named 16 new Damon Runyon Fellows, exceptional postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators.

28 Aug 2024

Breakthrough vaccine targets tick-borne bovine anaplasmosis in cattle

University of Missouri researchers are working to develop the first-ever vaccine proven to protect cattle from a devastating tick-borne cattle disease known as bovine anaplasmosis.

28 Aug 2024

Hereditary cardiac amyloidosis more common in the UK than previously thought

More people in the UK are at risk of a hereditary form of cardiac amyloidosis, a potentially fatal heart condition, than previously thought, according to a new study led by researchers at UCL (University College London) and Queen Mary University of London.

28 Aug 2024

CDCA7 identified as key player in hemimethylation sensing

DNA methylation is a process in which a methyl group is attached to the cytosine base of the DNA molecule, and a major way that DNA is epigenetically marked.

28 Aug 2024

Cell therapy commercialization: Streamline your path to cell therapy commercialization

Moving your cell therapy clinical trial beyond Phase I is an exciting time, marking a significant milestone. There are many therapeutic developers working to address critical patient needs in oncology, auto-immune, regenerative medicine, and other spaces.

From Charles Rivers Laboratories Cell and Gene Therapy 28 Aug 2024

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Gene News and Research

Latest Gene News and Research

Rare genetic mutation tied to increased risk of tuberculosis

Vutrisiran shows potential to become the new standard of care for rare heart disease

AI tool RENAISSANCE transforms creation of kinetic models in cellular metabolism

New consensus on assessing carcinogenic risks of gene therapies

Redefining 5hmC: More than just a stepping stone in the DNA demethylation pathway

CBL identified as the most promising potential biomarker for aortic dissection

Vancomycin resistance in Staphylococcus aureus may become more stable over time

Discovery of borderzone inflammation offers new avenues for heart failure prevention

New bacterial defense mechanism revealed as potential tool for genome editing

Study reveals key role of A20 protein in controlling inflammation in liver disease

Mapping DNA’s hidden knot-like structures may revolutionize disease treatment

AI unveils secrets of protein stability

New system can spot genetic markers of autism in brain images with high accuracy

Study reveals a new target for universal treatment for autoimmune diseases

Study reveals how bacteria pass on traits without DNA changes

16 promising postdoctoral scientists awarded Damon Runyon Fellowships for cancer research

Breakthrough vaccine targets tick-borne bovine anaplasmosis in cattle

Hereditary cardiac amyloidosis more common in the UK than previously thought

CDCA7 identified as key player in hemimethylation sensing

Cell therapy commercialization: Streamline your path to cell therapy commercialization

eBook: Using iPSCs models for human disease research and drug discovery eBook

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering