Gene News and Research

Latest Gene News and Research

Fruit fly protein shows protective effect on dopamine-producing neurons

Parkinson's disease is a neurodegenerative disorder that affects dopamine-producing or dopaminergic neurons. The progressive loss of these neurons is what leads to impairment in movement coordination in those suffering from the illness.

3 Oct 2018

Researchers create pseudo-embryos that mimic human embryos

Researchers have created murine pseudo-embryos that form the three major axes of the body and are able to accurately mimic human embryos.

3 Oct 2018

Genentech announces clinical data from studies investigating risdiplam in spinal muscular atrophy

Genentech, a member of the Roche Group, announced today interim clinical data from the dose-finding parts of the pivotal FIREFISH and SUNFISH studies investigating risdiplam in spinal muscular atrophy.

3 Oct 2018

Alnylam submits CTA application to MHRA to initiate Phase 1/2 study of ALN-AAT02

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today that it has submitted a Clinical Trial Authorization application to the Medicines and Healthcare products Regulatory Agency to initiate a Phase 1/2 study of ALN-AAT02, an investigational RNAi therapeutic targeting alpha-1 antitrypsin for the treatment of AAT deficiency-associated liver disease.

3 Oct 2018

Researchers insert just enough human DNA into mice to study preterm birth

Preterm birth remains a global epidemic linked to a lifetime of potential health complications. It also is difficult to study in living creatures--especially the uniquely precise biology of preterm birth in humans.

3 Oct 2018

Gene variant linked to Type 2 diabetes may predispose people to have lower body weight

A research team at the University of North Carolina at Chapel Hill's Gillings School of Global Public Health found that a well-known gene variant linked to Type 2 diabetes, called transcription Factor-7 like 2 gene, may also predispose someone to being leaner, or having a lower body weight.

3 Oct 2018

Hopkins gastroenterologists use endoscopic procedure to deliver therapeutic genes to the liver

Fixing or replacing faulty genes has emerged as a key to unlocking cures for numerous devastating diseases. But if the new, engineered genes can't find their way into the patient's genomic sequence, they won't help.

3 Oct 2018

Aggressive breast cancer hijacks normal protective physiological process to survive

A member of a protein family known for protecting our cells also protects cancer cells in aggressive, metastatic breast cancer, scientists report.

3 Oct 2018

Study sheds light on transport of enzyme involved in stem cell differentiation to DNA

Researchers at the Centre for Genomic Regulation in Barcelona, Spain, have identified the mechanism by which an important enzyme involved in the differentiation of stem cells is brought to the DNA.

3 Oct 2018

Study highlights need for population-specific precision medicine programs in Latin America

Drug safety and effectiveness vary greatly among populations worldwide. Genetics is one of the factors that contribute to variability in drug response.

3 Oct 2018

Carnegie professor receives NIH Director's New Innovator Award

Kathryn Whitehead, assistant professor of chemical engineering at Carnegie Mellon University, has been awarded a 2018 National Institutes of Health (NIH) Director's New Innovator Award for her project titled "Fate, Function, and Genetic Engineering of Breast Milk Cells for Infant Therapy."

3 Oct 2018

Some people can avoid depression by maintaining serotonin level throughout the year

Some people can adjust to environmental stressors to avoid depression. Women need to do this more than men to avoid getting depressed.

3 Oct 2018

Alnylam reports further progress on broadening the therapeutic potential of RNAi

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today further progress on the Company's platform efforts in extrahepatic delivery of novel siRNA conjugates, including central nervous system (CNS) and ocular delivery in rat and non-human primates (NHPs).

3 Oct 2018

Study: Phyloplankton's ability to generate resting stages plays key role in genetic differences

The genetic differences in phyloplankton living in close geographic proximity can be great, something which long has surprised researchers. Now new research shows that the ability of phyloplankton to generate resting stages can be an important part of the explanation.

1 Oct 2018

Study finds disease-causing mutation in French-Canadians

A team of Canadian scientists, including researchers at the Montreal Neurological Institute and Hospital has discovered the first French-Canadian founder mutation gene linked to synucleinopathies, a group of neurodegenerative diseases that includes Parkinson's disease, dementia with Lewy-Bodies and multiple system atrophy

1 Oct 2018

Genetic variants reveal novel therapeutic targets for chronic kidney disease

The kidney does more than double or even triple duty compared to other organs - it extracts waste, balances body fluids, forms urine, regulates blood pressure, and secretes hormones.

1 Oct 2018

TEAD1 protein appears to be important regulator of tumor migration in glioblastoma

A specific protein called TEAD1 is an important regulator of tumor migration in glioblastoma, the most common brain tumor in adults, and deactivating this protein may stop tumor cells from migrating away from the main tumor mass, according to research conducted at the Icahn School of Medicine at Mount Sinai and published October 1 in the journal Nature Communications.

1 Oct 2018

'Kidney-gene' plays role in the central nervous system and controls movement

The WT1 gene fulfills a central role in the development of a healthy, proper functioning kidney. Mutations in WT1 lead to impairments in kidney development and cause Wilms tumors, a pediatric kidney cancer.

1 Oct 2018

FDA permits marketing of ClonoSEQ assay to detect minimal residual disease in blood cancer patients

Today the U.S. Food and Drug Administration permitted marketing of ClonoSEQ assay, a next generation sequencing-based test for minimal residual disease in patients with acute lymphoblastic leukemiaor multiple myeloma. MRD is a measure of the amount of cancer cells remaining in a person's bone marrow.

30 Sep 2018

Researchers deplete key protein for DNA replication using protein degradation system

Researchers from Tokyo Metropolitan University and the FIRC Institute of Molecular Oncology in Italy have succeeded in depleting AND-1, a key protein for DNA replication, by using a recently developed conditional protein degradation system.

29 Sep 2018

Gene News and Research

Latest Gene News and Research

Fruit fly protein shows protective effect on dopamine-producing neurons

Researchers create pseudo-embryos that mimic human embryos

Genentech announces clinical data from studies investigating risdiplam in spinal muscular atrophy

Alnylam submits CTA application to MHRA to initiate Phase 1/2 study of ALN-AAT02

Researchers insert just enough human DNA into mice to study preterm birth

Gene variant linked to Type 2 diabetes may predispose people to have lower body weight

Hopkins gastroenterologists use endoscopic procedure to deliver therapeutic genes to the liver

Aggressive breast cancer hijacks normal protective physiological process to survive

Study sheds light on transport of enzyme involved in stem cell differentiation to DNA

Study highlights need for population-specific precision medicine programs in Latin America

Carnegie professor receives NIH Director's New Innovator Award

Some people can avoid depression by maintaining serotonin level throughout the year

Alnylam reports further progress on broadening the therapeutic potential of RNAi

Study: Phyloplankton's ability to generate resting stages plays key role in genetic differences

Study finds disease-causing mutation in French-Canadians

Genetic variants reveal novel therapeutic targets for chronic kidney disease

TEAD1 protein appears to be important regulator of tumor migration in glioblastoma

'Kidney-gene' plays role in the central nervous system and controls movement

FDA permits marketing of ClonoSEQ assay to detect minimal residual disease in blood cancer patients

Researchers deplete key protein for DNA replication using protein degradation system

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research