Gene News and Research

Latest Gene News and Research

Scientists identify mutation that makes tumor cells resistant to breast and ovarian cancer drug

Scientists have identified a mutation that gives cancer cells resistance to the breakthrough cancer treatment olaparib and other PARP inhibitors.

10 May 2018

Study discovers genetic variations that increase heart attack risk for statin patients

A Vanderbilt-led research team has discovered genetic variations that increase the risk of heart attack even when patients are receiving a statin drug like Lipitor or Crestor to lower their blood cholesterol.

10 May 2018

Researchers identify six genes that predispose carriers to develop medulloblastoma

Researchers have identified six genes that predispose carriers to develop the brain tumor medulloblastoma and have used the discovery to craft genetic counseling and screening guidelines. The study appears today in the journal The Lancet Oncology.

10 May 2018

New case study shows CAR T therapy as viable option for AML patients

Chimeric Antigen Receptor T-cell therapy, also known as CAR T therapy, was named the biggest research breakthrough of 2017 by the American Society of Clinical Oncology. The personal gene therapy utilizes a patient's own immune cells to fight cancer.

9 May 2018

International research collaboration aims to prevent heart arrhythmias with gene therapy

The most common and potentially lethal complication following a heart attack is the heart's inability to do one of its most basic jobs: beat at a normal rate.

9 May 2018

Advances in Cell Lineage Analysis

Dr. Jan Phillip Junker discusses the applications of CRISPR-Cas9 in cell lineage analysis and the development of tomo-seq; a method to study the spatial organization of cells within whole organisms.

9 May 2018

Disruption of the body's circadian rhythm linked to increased risk of breast cancer

For years, doctors have associated the BRCA1 and BRCA2 gene mutations with an increased risk of breast cancer.

9 May 2018

Scientists develop computer algorithm that reveals gene networks activated in cancer cell

Recent headlines have cast suspicion on social network analysis, which can mine data from the internet to target advertisements or potentially influence elections.

9 May 2018

ONC201 disrupts mitochondrial function and kills breast cancer cells, reveals study

TRAIL, a member of the TNF family of ligands, causes caspase-dependent apoptosis through activation of its receptors, death receptor 4 and DR5.

9 May 2018

Findings confirm analytical principle that describes mutational processes and cancer development

When a cell develops into a tumor, something has gone terribly wrong: the uncontrolled growth, invasion of nearby tissues and finally metastasis are the result of many consecutive DNA mutations.

9 May 2018

Researchers uncover the cause of scarring in idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is one of the most challenging and frustrating diseases that pulmonologists face.

9 May 2018

Allen Institute for Cell Science launches first predictive and comprehensive, 3D model of live human cell

The Allen Institute for Cell Science today launched the first predictive and comprehensive, 3D model of a live human cell, the Allen Integrated Cell.

9 May 2018

New findings point to potential therapeutic avenues for leukemia

Scientists have known for decades that the Hox family of transcription factors are key regulators in the formation of blood cells and the development of leukemia.

9 May 2018

Centrosome amplification may contribute to initiation of cancers, research suggests

Cells begin to accumulate centrosomes - organelles that play a vital role during cell division - before they transform into cancer cells, according to a new study of patients with Barrett's esophagus condition, which is associated with esophageal cancer.

8 May 2018

New drug-based treatment to promote weight loss in young patients with genetic obesity

In a new study researchers from the Institute for Experimental Pediatric Endocrinology of the Charité - Universitätsmedizin Berlin have successfully treat patients whose obesity is caused by a genetic defect.

8 May 2018

Alnylam achieves delivery of novel siRNAs conjugates to the central nervous system

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today that the Company has achieved delivery of novel small interfering RNA conjugates to the central nervous system and is planning to advance a pipeline of investigational RNAi therapeutics into clinical development.

8 May 2018

Gene News and Research

Latest Gene News and Research

Scientists identify mutation that makes tumor cells resistant to breast and ovarian cancer drug

Study discovers genetic variations that increase heart attack risk for statin patients

Researchers identify six genes that predispose carriers to develop medulloblastoma

New case study shows CAR T therapy as viable option for AML patients

International research collaboration aims to prevent heart arrhythmias with gene therapy

Advances in Cell Lineage Analysis

Disruption of the body's circadian rhythm linked to increased risk of breast cancer

Scientists develop computer algorithm that reveals gene networks activated in cancer cell

ONC201 disrupts mitochondrial function and kills breast cancer cells, reveals study

Findings confirm analytical principle that describes mutational processes and cancer development

Researchers uncover the cause of scarring in idiopathic pulmonary fibrosis

Allen Institute for Cell Science launches first predictive and comprehensive, 3D model of live human cell

New findings point to potential therapeutic avenues for leukemia

Centrosome amplification may contribute to initiation of cancers, research suggests

New drug-based treatment to promote weight loss in young patients with genetic obesity

Alnylam achieves delivery of novel siRNAs conjugates to the central nervous system

Researchers harness the precision of CRISPR to knock out single genes in yeast

Scientists discover a small family of proteins that control inclusion of DNA methylation marks in genome

PFKFB3 enzyme appears to play a key role in pulmonary hypertension

Using human induced pluripotent stem cells for therapeutic drug testing

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging