Gene News and Research

Latest Gene News and Research

Study uncovers promising new line of attack against aggressive prostate cancer

UC San Francisco researchers have discovered a promising new line of attack against lethal, treatment-resistant prostate cancer. Analysis of hundreds of human prostate tumors revealed that the most aggressive cancers depend on a built-in cellular stress response to put a brake on their own hot-wired physiology.

14 May 2018

Gene variant may be linked to worse psychiatric symptoms in TBI patients

A variant of the APOE gene may be linked to worse psychiatric symptoms in people who have had a traumatic brain injury, found a Veterans Affairs San Diego Healthcare System study. Study participants with both the gene variant and at least one TBI had more severe symptoms of PTSD, anxiety, and depression than comparison participants.

14 May 2018

New drug reduces symptoms of Rett syndrome in preclinical models

A new article published in the Cell Reports describes how a new drug is able to reduce the symptoms and activate the dormant neurons characteristic of Rett Syndrome in preclinical models.

14 May 2018

Scientists uncover genome variation linked to increased risk of developing Alzheimer's

An article published in Nature Medicine with the collaboration of the research group of Dr. Manel Esteller, director of the Epigenetics and Cancer Biology Program of the Bellvitge Biomedical Research Institute, ICREA Researcher and Professor of Genetics of the University of Barcelona, and Drs. Dave Monk and Isidre Ferrer, from the same center, shows that the inheritance of small changes in DNA alters the expression of the PM20D1 gene and is associated with an increased risk of developing Alzheimer's disease.

14 May 2018

Scientists design new computational strategy to enable more personalized cancer treatment

Mathematicians and cancer scientists have found a way to simplify complex biomolecular data about tumors, in principle making it easier to prescribe the appropriate treatment for a specific patient.

14 May 2018

Researchers use spheroids to screen for potential cancer drugs

Researchers from The Scripps Research Institute have reported a new and more effective way of screening for potential cancer drugs.

14 May 2018

Phase 1/2 study evaluates safety, tolerability of multiple-ascending doses of ARO-HBV in hepatitis B patients

Arrowhead Pharmaceuticals Inc. today announced that it has dosed the first 3 hepatitis B virus patients in the multiple-ascending dose portion of its ongoing Phase 1/2 study of ARO-HBV, the company's third generation subcutaneously administered RNA interference therapeutic being developed as a potentially curative therapy for patients with chronic HBV infection.

14 May 2018

Researchers report advances in efforts to improve treatment, prognosis of colorectal cancers

Georgios Margonis, M.D., Ph.D., a surgical oncology fellow at the Johns Hopkins University School of Medicine, and Matthew Weiss, M.D., surgical director of the Johns Hopkins Liver and Pancreas Cancer Multidisciplinary Clinics, report advances in efforts to improve the treatment and prognosis of colorectal cancers that have spread to the liver.

14 May 2018

LogicBio team to present data on preclinical effectiveness of GeneRide platform

LogicBio Therapeutics, Inc., a genetic medicine company founded to develop safe medicines with lasting therapeutic benefit for children with life-threatening diseases, today announced it will be presenting data on the company's technology and robust preclinical pipeline at the annual meeting of the American Society of Gene & Cell Therapy at the Hilton Chicago, from May 16-19, 2018.

14 May 2018

Havard University grants license to Beam Therapeutics to develop new base editing technology

Harvard University has granted a worldwide license to Beam Therapeutics, Inc., to develop and commercialize a suite of revolutionary DNA base editing technologies for the treatment of human disease.

14 May 2018

Why the drugmaker that paid Trump’s lawyer $1.2 million is so worried

President Donald Trump didn't mention Novartis or other drugmakers by name last year when he said the industry is "getting away with murder."

11 May 2018

CRISPR-based treatment can restore retinal function in mice with eye disease

Researchers from Columbia University have developed a new technique for the powerful gene editing tool CRISPR to restore retinal function in mice afflicted by a degenerative retinal disease, retinitis pigmentosa.

11 May 2018

UAB expert highlights need to do more trials in the epidemic center of disease

Frances Lund, Ph.D., the Charles H. McCauley Chair of Microbiology at the University of Alabama at Birmingham, spoke about chronic inflammatory disease and the striking correlation between location and disease incidence at the recent Fourth International Vatican Conference, "Unite to Cure."

11 May 2018

Scientists discover a mechanism through which HIV determines the fate and function of cells

A stem cell is one with infinite possibilities. So, for decades, scientists have puzzled over how the cell chooses to keep being a stem cell and continue dividing, or specialize into a specific cell type, like a heart or brain cell.

11 May 2018

New therapeutic strategy exploits acquired vulnerability in drug-resistant cancer

Cancer cells that develop resistance to drugs, pay a price for this, by simultaneously developing a new vulnerability. If this acquired vulnerability can be identified, it may be exploited clinically.

10 May 2018

Study finds way to better treat men with locally advanced prostate cancer

A new study published today has found a way to identify men with locally advanced prostate cancer who are less likely to respond well to radiotherapy.

10 May 2018

Enhancing the effects of vitamin D to curb type 2 diabetes

More than 27 million people in the United States are living with type 2 diabetes, according to the Centers for Disease Control and Prevention. As the population ages and a growing percentage of people become overweight or obese, that number is expected to increase.

10 May 2018

Gene News and Research

Latest Gene News and Research

Study uncovers promising new line of attack against aggressive prostate cancer

Gene variant may be linked to worse psychiatric symptoms in TBI patients

New drug reduces symptoms of Rett syndrome in preclinical models

Scientists uncover genome variation linked to increased risk of developing Alzheimer's

Scientists design new computational strategy to enable more personalized cancer treatment

Researchers use spheroids to screen for potential cancer drugs

Phase 1/2 study evaluates safety, tolerability of multiple-ascending doses of ARO-HBV in hepatitis B patients

Researchers report advances in efforts to improve treatment, prognosis of colorectal cancers

LogicBio team to present data on preclinical effectiveness of GeneRide platform

Havard University grants license to Beam Therapeutics to develop new base editing technology

Why the drugmaker that paid Trump’s lawyer $1.2 million is so worried

CRISPR-based treatment can restore retinal function in mice with eye disease

UAB expert highlights need to do more trials in the epidemic center of disease

Scientists discover a mechanism through which HIV determines the fate and function of cells

New therapeutic strategy exploits acquired vulnerability in drug-resistant cancer

Study finds way to better treat men with locally advanced prostate cancer

Enhancing the effects of vitamin D to curb type 2 diabetes

Researchers discover genetic signal common to cerebral palsy and autism

Study reveals the genetics underlying cerebral palsy and autism

Phase 2 study of dexpramipexole in hypereosinophilic syndromes meets its co-primary endpoints

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging