Gene News and Research

Latest Gene News and Research

Researchers make discovery about yeast metabolism that could help drug developers

Researchers at the Francis Crick Institute have developed machine learning algorithms that can predict the metabolism of yeast based on its protein content.

6 Sep 2018

GW researcher receives grant to examine link between liver fluke infection and bile duct cancer

Liver fluke infection is a major public health problem affecting more than 10 million people in Southeast Asia, particularly in Thailand and Laos. Infection has been strongly linked to cholangiocarcinoma, or bile duct cancer, an uncommon but aggressive form of cancer.

5 Sep 2018

Tipping the scales to initiate tumorigenesis in the colon

The regulatory protein c-MYC plays an important role in promoting the development of many types of tumors. c-MYC is a transcription factor that controls the activity of large numbers of genes involved in cell division, and its overexpression leads to excessive cell proliferation.

5 Sep 2018

Link discovered between tumor genome changes and mortality risk across cancer types

Researchers have discovered a link between certain changes in the genome of a tumor and increased chances of death across multiple types of cancer.

5 Sep 2018

Huntington's disease may take effect much earlier in life than previously believed, study suggests

A new study published in the Proceedings of the National Academy of Sciences suggests that Huntington's disease may take effect much earlier in life than was previously believed, and that a new drug may be key in controlling the disease.

5 Sep 2018

Research uncovers new mechanism involved in bone formation

Osteoporosis is a disease that causes bones to fracture easily due to a reduction in both bone mass and quality. Aging is one of its leading causes, and it is estimated that around 200 million people are affected worldwide.

5 Sep 2018

Scientists shed light on new possibilities for prevention of preterm birth

A team from the Research Institute of the McGill University Health Centre has shed light on new possibilities for the prevention of preterm birth.

5 Sep 2018

Gene therapy for rare genetic blindness wins prestigious Champalimaud Vision award

A team of seven researchers collaborating from United States and Britain have found a way to use gene therapy to cure a rare form of childhood blindness that occurs due to a genetic predisposition.

5 Sep 2018

Novel lentiviral model can determine effect of Wnt/β-Catenin inhibition on bone regeneration

Researchers have developed a novel tool for determining the sensitivity of bone healing to inhibition of the Wnt signaling pathway and have validated its use in a study of bone regeneration in mice.

4 Sep 2018

Study finds new clues to understand relapse in breast cancer

A large genomic analysis has linked certain DNA mutations to a high risk of relapse in estrogen receptor positive breast cancer, while other mutations were associated with better outcomes, according to researchers from Washington University School of Medicine in St. Louis, the Baylor College of Medicine and the University of British Columbia.

4 Sep 2018

Easy and inexpensive test could one day help guide epilepsy treatment

An easy and inexpensive test for the HLA-B*15:02 allele could one day allow clinicians to quickly identify which epilepsy patients are at risk of carbamazepine hypersensitivity, according to study results presented by Gita V. Soraya at ILAE's 2018 Asian & Oceanian Epilepsy Congress in Bali.

4 Sep 2018

Study provides absolute 10-year estimates for dementia by age, sex and APOE genotype

A Danish study provides 10-year absolute risk estimates for dementia specific to age, sex and common variation in the APOE gene, which may help identify high-risk individuals who potentially could benefit from early targeted prevention.

4 Sep 2018

Stanford researchers show how to prevent immune response to gene therapy in mouse model

Stanford University School of Medicine researchers have demonstrated that gene therapy can be effective without causing a dangerous side effect common to all gene therapy: an autoimmune reaction to the normal protein, which the patient's immune system is encountering for the first time.

4 Sep 2018

Study sheds light on how vaso-occlusive pain crises arise in sickle-cell disease

One of the most common complications of sickle-cell disease occurs when deformed red blood cells clump together, blocking tiny blood vessels and causing severe pain and swelling in the affected body parts.

4 Sep 2018

Gene editing could prevent the evolution of drug-resistant bacteria

Researchers have found a way of preventing the emergence of antibiotic-resistant bacteria, a promising new discovery in the fight against deadly superbugs.

3 Sep 2018

Genetic disruption strategy effectively stymies evolution of drug-resistant pathogens

A genetic disruption strategy developed by University of Colorado Boulder researchers effectively stymies the evolution of antibiotic-resistant bacteria such as E. coli, giving scientists a crucial leg up in the ongoing battle against deadly superbugs.

3 Sep 2018

Breakthrough study sheds light on mechanism underlying Warsaw Breakage Syndrome

Researchers from Tokyo Metropolitan University and the FIRC Institute of Molecular Oncology in Italy have uncovered a previously unknown function of the DDX11 helicase enzyme.

3 Sep 2018

Severity of asthma depends on genetic profile and air pollution

Asthma patients, with a specific genetic profile, exhibit more intense symptoms following exposure to traffic pollution, according to researchers at the National Institutes of Health and collaborators. The study appeared online in Scientific Reports.

31 Aug 2018

A genetic signal-transmission system for the gut microbiome

More than 1,000 species of bacteria have been identified in the human gut, and understanding this incredibly diverse "microbiome" that can greatly impact health and disease is a hot topic in scientific research.

31 Aug 2018

Arrowhead completes dosing of ARO-AAT Phase 1 study to treat rare genetic liver disease

Arrowhead Pharmaceuticals Inc. today announced that it has completed dosing of a Phase 1 clinical study of ARO-AAT, the company's second generation subcutaneously administered RNA interference therapeutic being developed as a treatment for a rare genetic liver disease associated with alpha-1 antitrypsin deficiency.

31 Aug 2018

Gene News and Research

Latest Gene News and Research

Researchers make discovery about yeast metabolism that could help drug developers

GW researcher receives grant to examine link between liver fluke infection and bile duct cancer

Tipping the scales to initiate tumorigenesis in the colon

Link discovered between tumor genome changes and mortality risk across cancer types

Huntington's disease may take effect much earlier in life than previously believed, study suggests

Research uncovers new mechanism involved in bone formation

Scientists shed light on new possibilities for prevention of preterm birth

Gene therapy for rare genetic blindness wins prestigious Champalimaud Vision award

Novel lentiviral model can determine effect of Wnt/β-Catenin inhibition on bone regeneration

Study finds new clues to understand relapse in breast cancer

Easy and inexpensive test could one day help guide epilepsy treatment

Study provides absolute 10-year estimates for dementia by age, sex and APOE genotype

Stanford researchers show how to prevent immune response to gene therapy in mouse model

Study sheds light on how vaso-occlusive pain crises arise in sickle-cell disease

Gene editing could prevent the evolution of drug-resistant bacteria

Genetic disruption strategy effectively stymies evolution of drug-resistant pathogens

Breakthrough study sheds light on mechanism underlying Warsaw Breakage Syndrome

Severity of asthma depends on genetic profile and air pollution

A genetic signal-transmission system for the gut microbiome

Arrowhead completes dosing of ARO-AAT Phase 1 study to treat rare genetic liver disease

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research