Gene News and Research

Latest Gene News and Research

Study reveals mechanisms underlying inflammatory response in the brain associated with fever

Researchers from Kanazawa University report in Journal of Neuroscience performed a microdialysis study on mice to determine mechanisms underlying the inflammatory response in the brain associated with fever that might be used to develop new strategies for treatment.

31 Aug 2018

Researchers predict how splicing errors impact disease risk

No one knows how many times in a day, or even an hour, the trillions of cells in our body need to make proteins.

31 Aug 2018

Research may hold key to unlocking cause and finding treatment for age-related hearing loss

Age-related hearing loss is among the top three chronic conditions affecting adults 65 years or older, according to the National Center for Health Statistics.

31 Aug 2018

Muscle dystrophy treatment in dogs with Crispr gene editing

Researchers in the United States have shown that genetically caused muscular dystrophy in dogs could be corrected using genetic editing tools. Muscular dystrophy is one of the most common fatal genetic conditions seen in children and is also seen in dogs

31 Aug 2018

Study raises possibility of detecting childhood bone cancers earlier

Scientists have discovered that some childhood bone cancers start growing years before they are currently diagnosed.

30 Aug 2018

New genetic marker could improve diagnosis of prostate cancer

Scientists have discovered a link between certain genetic mutations, the aggressiveness of prostate cancer, risk of developing the disease and poorer survival rates of patients.

30 Aug 2018

Pfizer terminates clinical studies evaluating domagrozumab for treatment of Duchenne muscular dystrophy

Pfizer Inc. announced today that it is terminating two ongoing clinical studies evaluating domagrozumab (PF-06252616) for the treatment of Duchenne muscular dystrophy (DMD): a Phase 2 safety and efficacy study (B5161002) and an open-label extension study (B5161004).

30 Aug 2018

EC grants marketing authorization for ONPATTRO (patisiran) in Europe

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today that the European Commission (EC) has granted marketing authorization for ONPATTRO (patisiran) for the treatment of hereditary transthyretin-mediated (hATTR) amyloidosis in adults with stage 1 or stage 2 polyneuropathy.

30 Aug 2018

Study yields therapeutic clues to combat drug resistance in rare aggressive cancer

Stephen Elledge, PhD, and his team did not set out to find therapies that could render tumors less resistant to therapy or make existing drugs more potent against a rare form of cancer. But these are precisely the clinical insights that their most recent study has yielded.

29 Aug 2018

Using novel gene therapy to cure infants born with severe combined immunodeficiency

Out of every 60,000 births, a baby arrives to face the world without a fully functioning immune system leaving them unequipped to fight even the most common infections.

29 Aug 2018

Researchers uncover why some cancers grow faster than others

University of Toronto researchers have uncovered why some cancers grow faster than others. The team led by Liliana Attisano, Professor in U of T's Donnelly Centre for Cellular and Biomolecular Research, has identified a protein called NUAK2, which is produced by cancer cells to boost their proliferation and whose presence in tumors is associated with poor disease prognosis.

29 Aug 2018

Lack of protein in father's diet can impact long-term health of his offspring

New research has shown that a lack of protein in a father's diet affects sperm quality which can have a direct impact on the long-term health of their offspring.

29 Aug 2018

Researchers discover reason why many bladder cancer patients do not respond to immunotherapy

Mount Sinai researchers have discovered that a particular type of cell present in bladder cancer may be the reason why so many patients do not respond to the groundbreaking class of drugs known as PD-1 and PD-L1 immune checkpoint inhibitors, which enable the immune system to attack tumors.

29 Aug 2018

Research shows proteomics can be used to predict evolution of triple negative breast cancer

The rarest, but also the most aggressive and hard to treat form of breast cancer, is known as triple negative. For this type of cancer, researchers have so far been unable to identify markers that can classify patients by prognosis or probability of responding to different treatments.

29 Aug 2018

Cherwell confirms support for conference addressing key challenges in aseptic manufacturing of ATMPs

Cherwell Laboratories, supplier of environmental monitoring and process validation products, has confirmed its continued support for the Pharmaceutical & Healthcare Sciences Society - UCL Q3P Annual Conference 2018.

29 Aug 2018

Researchers discover mechanism that steers growth of cancer cells in melanoma and liver cancer

Melanoma and liver cancer are becoming more widespread in Europe and the US. Whilst both diseases progress very differently, they are among the types of cancer which are most likely to be fatal in the Western world.

29 Aug 2018

Researchers find how NF2 gene mutations lead to out-of-control cellular proliferation

A team of Massachusetts General Hospital Cancer Center researchers has determined one way that mutations in a gene involved in a rare, hereditary cancer syndrome lead to out-of-control cellular proliferation.

29 Aug 2018

Scientists reveal how immune system strives to protect the lungs of infants with flu

The immune system appears to put a premium on maintaining lung function in infants infected with the influenza virus by mounting a rapid response to repair damaged cells, according to research led by St. Jude Children’s Research Hospital. The findings appear today in the scientific journal Immunity.

29 Aug 2018

Researchers enlist genes that control production of cellular energy stored in ATP molecules

Everything the body does--your brain thinking, your heart beating, your cells growing--requires energy. Consequently, it comes as no surprise that disruptions in energy production can contribute to a wide range of diseases.

29 Aug 2018

Cannabis use and mental illness link found

A large new study has found that people with mental ailments such as schizophrenia are more genetically inclined to use cannabis.

29 Aug 2018

Gene News and Research

Latest Gene News and Research

Study reveals mechanisms underlying inflammatory response in the brain associated with fever

Researchers predict how splicing errors impact disease risk

Research may hold key to unlocking cause and finding treatment for age-related hearing loss

Muscle dystrophy treatment in dogs with Crispr gene editing

Study raises possibility of detecting childhood bone cancers earlier

New genetic marker could improve diagnosis of prostate cancer

Pfizer terminates clinical studies evaluating domagrozumab for treatment of Duchenne muscular dystrophy

EC grants marketing authorization for ONPATTRO (patisiran) in Europe

Study yields therapeutic clues to combat drug resistance in rare aggressive cancer

Using novel gene therapy to cure infants born with severe combined immunodeficiency

Researchers uncover why some cancers grow faster than others

Lack of protein in father's diet can impact long-term health of his offspring

Researchers discover reason why many bladder cancer patients do not respond to immunotherapy

Research shows proteomics can be used to predict evolution of triple negative breast cancer

Cherwell confirms support for conference addressing key challenges in aseptic manufacturing of ATMPs

Researchers discover mechanism that steers growth of cancer cells in melanoma and liver cancer

Researchers find how NF2 gene mutations lead to out-of-control cellular proliferation

Scientists reveal how immune system strives to protect the lungs of infants with flu

Researchers enlist genes that control production of cellular energy stored in ATP molecules

Cannabis use and mental illness link found

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research