Gene News and Research

Latest Gene News and Research

Study shows that rogue proteins may underlie some ALS and frontotemporal dementia cases

ALS -- amyotrophic lateral sclerosis -- is a neurodegenerative disease that attacks motor neurons in the brain and spinal cord, slowly robbing its victims of their ability to walk, talk, breathe and swallow.

20 Aug 2018

New integrated gene logic-chips could have great value in medical care

Gene expression is a fundamental of life, where each cell switches on and off specific genes. Thus, an autonomous device that could control the on-off switching would have great value in medical care.

20 Aug 2018

Understanding How Antibodies Shape the Gut Microbiome

Dr. Keiichiro Suzuki discusses the importance of IgA in the human body, and his recent research study, which showed that IgA interacts with the gut microbiome and promotes the growth of healthy bacteria.

20 Aug 2018

New assay may help improve both sarcoma diagnosis and treatment

Sarcomas are rare tumors that are often misdiagnosed. Specific recurrent chromosomal rearrangements, known as translocations, can serve as essential diagnostic markers and are found in about 20 percent of sarcomas.

20 Aug 2018

Research explores relationship between personal history of infectious fever and cancer risk

Recurring patterns in patient accounts suggest the existence of an inverse relationship between personal history of infectious fever and cancer risk, and these patterns are documented throughout decades of medical literature.

17 Aug 2018

Scientists introduce microfluidics-based chip for manipulation and analysis of single cells

A few little cells that are different from the rest can have a big effect. For example, individual cancer cells may be resistant to a specific chemotherapy--causing a relapse in a patient who would otherwise be cured. In the journal Angewandte Chemie, scientists have now introduced a microfluidics-based chip for the manipulation and subsequent nucleic-acid analysis of individual cells.

17 Aug 2018

Researchers discuss techniques to help combat growing epidemic of obesity

More than 60 percent of American adults weigh more than is healthy, which results in increased health issues for the patient and high health care costs.

17 Aug 2018

Researchers develop new approach to study how tuberculosis infects people

Tuberculosis is one of the top 10 causes of death worldwide. Nearly 2 million people die every year from this infectious disease, and an estimated 2 billion people are chronically infected.

17 Aug 2018

New CRISPR technology may help eliminate mutated gene sequence

In a new study in cells, University of Illinois researchers have adapted CRISPR gene-editing technology to cause the cell's internal machinery to skip over a small portion of a gene when transcribing it into a template for protein building.

17 Aug 2018

New project to combat DMD-related fibrosis receives major funding boost

Duchenne muscular dystrophy is one of the most common congenital diseases in the world, affecting one in 3,500 Canadian males. DMD is caused by mutations in the dystrophin gene that results in progressive muscle degeneration and there are currently no effective treatments for DMD.

17 Aug 2018

Female mosquitoes quickly evolve selective mating behavior when faced with threats

Certain female mosquitoes quickly evolve more selective mating behavior when faced with existential threats from other invasive mosquito species, with concurrent changes to certain genetic regions, according to new research from North Carolina State University.

17 Aug 2018

Bacterial activity in child's mouth may serve as biomarkers for autism spectrum disorder

New research suggests that shifts in the bacteria within a child's mouth could provide objective biomarkers for identifying autism spectrum disorder.

17 Aug 2018

Lowering pH inside tumor cells can slow down spread of cancer

A new study focusing on the environment inside cancer cells may lead to new targeted treatment strategies.

17 Aug 2018

Research uncovers miscarriage cause, identifies potential targets for treatment

Tragic miscarriages for a couple have led to a discovery with potentially broad implications for future disease treatments, according to a team of researchers at the University of North Carolina School of Medicine. They identified a previously undiscovered gene mutation underlying hydrops fetalis – a fatal condition to fetuses due to fluid buildup in the space between organs.

16 Aug 2018

Study finds role of autoimmunity in development of COPD

Autoimmunity plays a role in the development of chronic obstructive pulmonary disease (COPD), according to a study led by Georgia State University and Vanderbilt University Medical Center that analyzed human genome information stored in Vanderbilt's DNA biobank.

16 Aug 2018

FDA expands approval of Vertex' cystic fibrosis medicine to treat children aged 12 to <24 months

Vertex Pharmaceuticals Incorporated today announced the U.S. Food and Drug Administration approved KALYDECO® (ivacaftor) to include use in children with cystic fibrosis ages 12 to <24 months who have at least one mutation in their cystic fibrosis transmembrane conductance regulator gene that is responsive to KALYDECO based on clinical and/or in vitro assay data.

16 Aug 2018

Study provides new insight into how 'trash bag of the cell' traps and seals off waste

The mechanics behind how an important process within the cell traps material before recycling it has puzzled scientists for years. But Penn State researchers have gained new insight into how this process seals off waste, much like a trash bag.

16 Aug 2018

Trial shows PARP inhibitor as novel treatment option for patients with advanced breast cancers

In a randomized, Phase III trial led by researchers at The University of Texas MD Anderson Cancer Center, the PARP inhibitor talazoparib extended progression-free survival (PFS) and improved quality-of-life measures over available chemotherapies for patients with metastatic HER2-negative breast cancer and mutations in the BRCA1/2 genes.

16 Aug 2018

Penn researchers develop first mouse model of idiopathic pulmonary fibrosis

The biggest hurdle to finding effective therapies for idiopathic pulmonary fibrosis (IPF) – a life-threatening condition in which the lungs become scarred and breathing is increasingly difficult – has been the inability to fully model the disease in animals, limiting the ability to observe and understand the disease.

16 Aug 2018

Mount Sinai study could transform treatment for patients with retinal degenerative diseases

Researchers at Mount Sinai have successfully restored vision in mice through activating retinal stem cells, something that has never been done before. Their study, published in the August 15 online issue of Nature, could transform treatment for patients with retinal degenerative diseases, which currently have no cure.

16 Aug 2018

Gene News and Research

Latest Gene News and Research

Study shows that rogue proteins may underlie some ALS and frontotemporal dementia cases

New integrated gene logic-chips could have great value in medical care

Understanding How Antibodies Shape the Gut Microbiome

New assay may help improve both sarcoma diagnosis and treatment

Research explores relationship between personal history of infectious fever and cancer risk

Scientists introduce microfluidics-based chip for manipulation and analysis of single cells

Researchers discuss techniques to help combat growing epidemic of obesity

Researchers develop new approach to study how tuberculosis infects people

New CRISPR technology may help eliminate mutated gene sequence

New project to combat DMD-related fibrosis receives major funding boost

Female mosquitoes quickly evolve selective mating behavior when faced with threats

Bacterial activity in child's mouth may serve as biomarkers for autism spectrum disorder

Lowering pH inside tumor cells can slow down spread of cancer

Research uncovers miscarriage cause, identifies potential targets for treatment

Study finds role of autoimmunity in development of COPD

FDA expands approval of Vertex' cystic fibrosis medicine to treat children aged 12 to <24 months

Study provides new insight into how 'trash bag of the cell' traps and seals off waste

Trial shows PARP inhibitor as novel treatment option for patients with advanced breast cancers

Penn researchers develop first mouse model of idiopathic pulmonary fibrosis

Mount Sinai study could transform treatment for patients with retinal degenerative diseases

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research