Gene News and Research

Latest Gene News and Research

Researchers highlight the need to reconsider mitochondrial replacement moratorium

Mothers with mitochondrial DNA mutations often give birth to children who face incurable and fatal illnesses. But a much-studied form of mitochondrial replacement could prevent the transmission of such diseases from mothers to children, researchers say.

28 Mar 2018

Researchers aim to reveal new direction for Barth syndrome treatment

The Barth Syndrome Foundation recently announced awardees from its 2017 grant cycle. Miriam Greenberg, Ph.D., professor of biological sciences in the College of Liberal Arts and Sciences at Wayne State University and a resident of Ann Arbor, Michigan, received a one-year, $50,000 grant for the project, "Cardiolipin activates pyruvate dehydrogenase (PDH) - a potential new target for treatment of Barth syndrome."

28 Mar 2018

Largest-ever study uncovers new genetic contributors to stroke

An international research group, including scientists at the University of Maryland School of Medicine, studying 520,000 people from around the world has identified 22 new genetic risk factors for stroke, tripling the number of gene regions known to affect stroke risk.

28 Mar 2018

New gene therapy may help the brain to heal following stroke and other injuries

Researchers have discovered a genetic trigger that may improve the brain’s ability to heal in conditions such as stroke, concussion and spinal cord injury.

28 Mar 2018

EPFL researchers uncover how the circadian clock regulates 3D chromatin structure

EPFL biologists and geneticists have uncovered how the circadian clock orchestrates the 24-hour cycle of gene expression by regulating the structure of chromatin, the tightly wound DNA-protein complex of the cell. The work is published in Genes & Development.

28 Mar 2018

FDA-approved inhibitors could be repurposed to target ARID1A-mutant ovarian cancers

Wistar researchers have found rationale for repurposing a class of antitumor compounds called HDAC inhibitors, already approved by the FDA for the treatment of diseases such as leukemia, as a new therapeutic option for ovarian cancer with mutations in the ARID1A gene.

27 Mar 2018

Study uncovers genetic trigger that may help the brain to recover from stroke, other injuries

Scientists have found a genetic trigger that may improve the brain's ability to heal from a range of debilitating conditions, from strokes to concussions and spinal cord injuries.

27 Mar 2018

UC researcher granted patent for potential pulmonary infection treatment

A researcher in the University of Cincinnati (UC) College of Medicine has been granted a U.S. patent for a potential treatment for a pulmonary infection in patients with cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD).

27 Mar 2018

Scientists use CRISPR to develop a genome surveillance tool

Scientists have converted CRISPR/Cas9 into a genome surveillance tool, in an effort to develop a more effective way of fighting disease.

27 Mar 2018

Stigma associated with Alzheimer's may prevent people from getting early diagnosis, treatment

Stigma associated with Alzheimer's disease may be an obstacle for individuals to seek information about their risk of developing Alzheimer's disease and to participate in clinical studies that discover potential therapies.

27 Mar 2018

Study identifies genetic factors linked to severity of acute viral bronchiolitis

A scientific study conducted at the State University of Campinas (UNICAMP) in São Paulo State, Brazil, has identified genetic factors associated with the severity of acute viral bronchiolitis. The study was supported by the Sao Paulo Research Foundation - FAPESP. Its results were published in the journal Gene.

27 Mar 2018

MSU scientists test promising drug to prevent cancer in high-risk patients

Michigan State University scientists are testing a promising drug that may stop a gene associated with obesity from triggering breast and lung cancer, as well as prevent these cancers from growing.

27 Mar 2018

Antibody sweeps away Alzheimer's plaques in mice

Years before people start showing characteristic symptoms of Alzheimer's disease, sticky plaques begin forming in their brains, damaging nearby cells. For decades, doctors have sought ways to clear out these plaques as a way to prevent or treat the disease.

27 Mar 2018

Research provides better understanding of how some cancer cells resist treatment

An international team of researchers led by Lucio Miele, MD, PhD, Professor and Chair of Genetics at LSU Health New Orleans School of Medicine, and Justin Stebbing, BM BCh MA, PhD, Professor of Cancer Medicine and Medical Oncology at Imperial College of Medicine in London, has found new genetic mutations that promote the survival of cancer cells.

23 Mar 2018

Researchers probe RNA epigenetics and chromatin structures to predict drug resistance in leukemia

Drug resistance is a major obstacle to effective treatment for patients with cancer and leukemia. Epigenetic modifying drugs have been proven effective for some patients with hematologic malignancies, such as myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML).

23 Mar 2018

Gene News and Research

Latest Gene News and Research

Researchers highlight the need to reconsider mitochondrial replacement moratorium

Researchers aim to reveal new direction for Barth syndrome treatment

Largest-ever study uncovers new genetic contributors to stroke

New gene therapy may help the brain to heal following stroke and other injuries

EPFL researchers uncover how the circadian clock regulates 3D chromatin structure

FDA-approved inhibitors could be repurposed to target ARID1A-mutant ovarian cancers

Study uncovers genetic trigger that may help the brain to recover from stroke, other injuries

UC researcher granted patent for potential pulmonary infection treatment

Scientists use CRISPR to develop a genome surveillance tool

Stigma associated with Alzheimer's may prevent people from getting early diagnosis, treatment

Study identifies genetic factors linked to severity of acute viral bronchiolitis

MSU scientists test promising drug to prevent cancer in high-risk patients

Antibody sweeps away Alzheimer's plaques in mice

Research provides better understanding of how some cancer cells resist treatment

Researchers probe RNA epigenetics and chromatin structures to predict drug resistance in leukemia

Researchers characterize S. aureus gene involved in virulence and antibiotic resistance

Genetic mutation that may protect people from malaria found to be more common

Mutations found in bassoon gene may help explain cause of rare brain disorder

Researchers uncover cause of rare childhood neurodegenerative disease

Restoring enzyme may help reverse effects of vascular aging, study shows

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