Gene News and Research

Latest Gene News and Research

Researchers discover genetic mutation underlying debilitating childhood brain disorder

Ashleigh Schaffer, PhD, assistant professor of genetics at Case Western Reserve University School of Medicine, and a team of global genetics experts have discovered a genetic mutation and the faulty development process it triggers, causing a debilitating brain-based disorder in children.

9 Aug 2018

Scientists find new molecular biomarker for gastric cancer

Although immunotherapy is seen as a very promising treatment for cancer, currently only 20 to 30 percent of patients respond positively. Being able to identify the people most likely to benefit from the costly therapy is a Holy Grail for oncologists.

9 Aug 2018

Study provides snapshot of mechanism behind cancer metastasis for the first time

Metastasis, or the formation of secondary tumors, is a leading contributor to the vast majority of deaths related to cancer.

9 Aug 2018

Scientists identify key neurobiological mechanisms that control aggression

A number of psychiatric disorders present with aggression and violence, which, needless to say, are destructive to both individuals and societies worldwide: death, disease, disability, and numerous socioeconomic problems can often be traced back to aggressive behavior.

9 Aug 2018

Scientists find genetic marker that indicates a person's risk for tachycardia-induced cardiomyopathy

Scientists in Japan have found a potential marker to identify which people with abnormally fast heartbeats are at high risk of developing heart failure.

9 Aug 2018

ETH scientists discover new cancer-specific molecular changes in tumor tissues

A research team led by Gunnar Raetsch, Professor of Biomedical Informatics at ETH Zurich, has evaluated the largest set of genetic data in cancer medicine: The Cancer Genome Atlas in the United States.

9 Aug 2018

Study finds false negatives in common tests used to determine ROS1 status in lung cancer

Drugs like crizotinib are used to treat patients with ROS1-positive lung cancer. But which patients are ROS1-positive? A University of Colorado Cancer Center study published in the Journal of Thoracic Oncology shows that common laboratory tests used to determine ROS1 status all have inherent limitations that can lead to false-negative results.

9 Aug 2018

Atlas of the nervous system provides new clues about origin of neurological diseases

Researchers at Karolinska Institutet have created a systematic and detailed map of the cell types of the mouse nervous system.

9 Aug 2018

Gene considered as tumor promoter may also halt development of cancer, shows study

A gene that has for decades been considered a tumor promoter, the PLK1 gene, can also perform the exact opposite function: halting the development of cancer.

9 Aug 2018

Study identifies distinct genetic mutations in appendix cancer that may impact treatment

The rarity of appendix cancer, accounting for less than 1 percent of tumors that originate in the gastrointestinal tract, and the lack of scientific data for this disease means that current treatment guidelines recommend applying therapies to people with appendix cancer that are intended for those with colon cancer.

9 Aug 2018

Researchers develop new method for capturing dynamic processes in individual cells

Researchers at Karolinska Institutet and Harvard Medical School report in the journal Nature that they have developed a technique for capturing dynamic processes in individual cells. Apart from studying disease processes, the method can be used to observe in detail how specialised cells are formed during embryonic development.

9 Aug 2018

Scientists identify drug that could reverse pulmonary arterial hypertension

Scientists at Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago took a major step toward developing a new treatment for pulmonary arterial hypertension, a severe lung disease with a five-year survival rate of 50 percent.

9 Aug 2018

LSU Health research may lead to a change in worldwide obesity prevention strategy

A team of LSU Health New Orleans researchers has found a lower prevalence of overweight and obesity among youth in Grenada compared to US adolescents.

7 Aug 2018

Scientists identify two potential new drug targets for treatment of HIV

Johns Hopkins scientists report they have identified two potential new drug targets for the treatment of HIV. The finding is from results of a small, preliminary study of 19 people infected with both HIV - the virus that causes AIDS - and the hepatitis C virus.

7 Aug 2018

New study identifies genes linked to higher risk for triple-negative breast cancer

A new study published in the Journal of the National Cancer Institute has identified specific genes associated with increased risk for triple-negative breast cancer, providing the basis for better risk management.

7 Aug 2018

Silencing of GULP1 gene expression plays important role in ovarian carcinogenesis

Johns Hopkins researchers in collaboration with Insilico Medicine, a biotechnology company based in Rockville Maryland, identify that silencing of the GULP1 gene expression by methylation plays an important role in ovarian carcinogenesis.

7 Aug 2018

Inhibition of NOVA1 gene helps prevent growth of lung cancer tumors

Researchers have identified a gene that when inhibited or reduced, in turn, reduced or prevented human non-small cell lung cancer tumors from growing.

7 Aug 2018

Study could lead to new diagnostic blood test for Kawasaki disease

For the first time, researchers at University of California San Diego School of Medicine and Imperial College London, with international collaborators, have determined that Kawasaki Disease (KD) can be accurately diagnosed on the basis of the pattern of host gene expression in whole blood. The finding could lead to a diagnostic blood test to distinguish KD from other infectious and inflammatory conditions.

6 Aug 2018

Unique experimental vaccine against Zika virus proves powerful in mice

A uniquely designed experimental vaccine against Zika virus has proven powerful in mice, new research has found.

6 Aug 2018

New study finds key factors behind differences in immune responses

Age, sex, and specific human genetic variants are the key factors behind differences between immune responses among healthy humans, finds a study of 1,000 individuals carried out by EPFL and the Pasteur Institute.

6 Aug 2018

Gene News and Research

Latest Gene News and Research

Researchers discover genetic mutation underlying debilitating childhood brain disorder

Scientists find new molecular biomarker for gastric cancer

Study provides snapshot of mechanism behind cancer metastasis for the first time

Scientists identify key neurobiological mechanisms that control aggression

Scientists find genetic marker that indicates a person's risk for tachycardia-induced cardiomyopathy

ETH scientists discover new cancer-specific molecular changes in tumor tissues

Study finds false negatives in common tests used to determine ROS1 status in lung cancer

Atlas of the nervous system provides new clues about origin of neurological diseases

Gene considered as tumor promoter may also halt development of cancer, shows study

Study identifies distinct genetic mutations in appendix cancer that may impact treatment

Researchers develop new method for capturing dynamic processes in individual cells

Scientists identify drug that could reverse pulmonary arterial hypertension

LSU Health research may lead to a change in worldwide obesity prevention strategy

Scientists identify two potential new drug targets for treatment of HIV

New study identifies genes linked to higher risk for triple-negative breast cancer

Silencing of GULP1 gene expression plays important role in ovarian carcinogenesis

Inhibition of NOVA1 gene helps prevent growth of lung cancer tumors

Study could lead to new diagnostic blood test for Kawasaki disease

Unique experimental vaccine against Zika virus proves powerful in mice

New study finds key factors behind differences in immune responses

eBook: Using iPSCs models for human disease research and drug discovery eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research