Gene News and Research

Latest Gene News and Research

Research elucidates maturation of cancer-causing miRNAs

An international research team led by Helmholtz Zentrum München, Technical University of Munich and the University of Edinburgh has used an integrated structural biological approach to elucidate the maturation of a cancer-causing microRNA in gene regulation.

4 Jul 2018

Study explains why men are more at risk for neurodevelopmental disorders

A new study has shed light on the reason why males are more at risk than females for neurodevelopmental disorders such as autism, schizophrenia and ADHD.

4 Jul 2018

SATB1 protein important for maintaining pluripotency of hematopoietic stem cells

Osaka University scientists demonstrate that SATB1 is important for maintaining pluripotency of hematopoietic stem cells

4 Jul 2018

Mount Sinai study identifies potential new treatment target for aggressive bladder cancer

A potential new target for treatment has been identified in an aggressive form of bladder cancer, Mount Sinai researchers report.

4 Jul 2018

People with exposure to paint or other solvents more likely to develop MS

People who have been exposed to paint, varnish and other solvents and who also carry genes that make them more susceptible to developing multiple sclerosis may be at much greater risk of developing the disease than people who have only the exposure to solvents or the MS genes, according to a study published in the July 3, 2018, online issue of Neurology, the medical journal of the American Academy of Neurology.

4 Jul 2018

New clues may lead to rapid detection of sepsis

Sepsis is an infection that kills as many Americans each year as stroke and Alzheimer's combined-about 250,000-but very little has changed in the treatment of this age-old scourge.

3 Jul 2018

New computational strategy used to identify genes associated with childhood cancer

Using a new computational strategy, researchers at UT Southwestern Medical Center have identified 29 genetic changes that can contribute to rhabdomyosarcoma, an aggressive childhood cancer.

3 Jul 2018

Researchers find new metabolic vulnerability in small cell lung cancer

Researchers at the Children's Medical Center Research Institute at UT Southwestern (CRI) have discovered a new metabolic vulnerability in small cell lung cancer (SCLC) that can be targeted by existing drug therapies.

3 Jul 2018

Researchers develop switch that can control genome editing

Researchers have developed a biological switch that reliably triggers protein expression and enables the control of genome editing tools.

3 Jul 2018

Scientists develop new understanding of how psychiatric diseases manifest and can be treated

Research scientists from The Feinstein Institute for Medical Research and the Donald and Barbara Zucker School of Medicine at Hofstra/Northwell in Hempstead, NY, in conjunction with their colleagues at Rockefeller University in New York City, have developed a new understanding of how certain psychiatric diseases - those that involve uncontrollable reactions to stimuli such as the high and low experiences attributed to bi-polar disorder, the impulsivity of an individual suffering from attention deficit hyperactivity disorder, and even suicidality - manifest and potentially can be treated. These findings were published today in Proceedings of the National Academy of Sciences.

3 Jul 2018

Researchers develop new methods for studying evolution of cancer treatment resistance

New methods of studying the evolution of treatment resistance in head and neck cancer are being developed by researchers at the Johns Hopkins Kimmel Cancer Center.

3 Jul 2018

Researchers identify molecular mechanism leading to cortical malformation from brain-only mutations

Focal malformations of cortical development are a heterogeneous group of brain cortical abnormalities.

2 Jul 2018

Compounds found in green tea and red wine offer hope to treat inborn congenital metabolic diseases

A new Tel Aviv University study suggests there is hope of treating certain inborn congenital metabolic diseases -- a hope found in green tea and in red wine.

2 Jul 2018

New biomarker paves way for personalized bladder cancer treatments

Researchers have identified a potential new target for the treatment of a particularly aggressive form of bladder cancer, in the form of microRNA.

2 Jul 2018

Cilia appears to play key role in formation of melanoma

Most cells in the human body have a cilium, a slender cell protuberance that picks up signals from the cell's external environment.

2 Jul 2018

Simple DNA test can predict risk of bad side effects to thiopurine drugs

Screening a tiny section of DNA could help East Asian patients avoid severe reactions to some medications.

2 Jul 2018

Streamlining and translating basic science discoveries into the clinic

To make sure that good ideas to enhance healthcare are not lost due to a lack of resources, a growing number of centers at Penn Medicine organize forums to pitch ideas to improve medical devices and technology, hold annual competitions to fund studies to improve patient care while keeping costs down, and sponsor seed grants for programs focused on patients who need individualized tailoring of their treatment.

2 Jul 2018

Researchers discover gene that plays role in regulating body's immune response to infection

Australia's national science agency CSIRO has identified a new gene that plays a critical role in regulating the body's immune response to infection and disease.

2 Jul 2018

Individuals may react differently to environmental chemicals based upon genetic profile

Why do individuals respond differently to the same environment? Researchers from North Carolina State University and Oregon State University have pinpointed a genetic difference in zebrafish tied to differing responses to the same environmental chemical.

30 Jun 2018

City of Hope receives $3.7 million from CIRM to develop phase 1 glioblastoma trial

The California Institute for Regenerative Medicine board has awarded City of Hope $3.7 million to develop a phase 1 clinical trial for glioblastoma patients that will genetically engineer their stem cells to better tolerate chemotherapy's side effects, allowing them to receive higher doses of the therapy.

30 Jun 2018

Gene News and Research

Latest Gene News and Research

Research elucidates maturation of cancer-causing miRNAs

Study explains why men are more at risk for neurodevelopmental disorders

SATB1 protein important for maintaining pluripotency of hematopoietic stem cells

Mount Sinai study identifies potential new treatment target for aggressive bladder cancer

People with exposure to paint or other solvents more likely to develop MS

New clues may lead to rapid detection of sepsis

New computational strategy used to identify genes associated with childhood cancer

Researchers find new metabolic vulnerability in small cell lung cancer

Researchers develop switch that can control genome editing

Scientists develop new understanding of how psychiatric diseases manifest and can be treated

Researchers develop new methods for studying evolution of cancer treatment resistance

Researchers identify molecular mechanism leading to cortical malformation from brain-only mutations

Compounds found in green tea and red wine offer hope to treat inborn congenital metabolic diseases

New biomarker paves way for personalized bladder cancer treatments

Cilia appears to play key role in formation of melanoma

Simple DNA test can predict risk of bad side effects to thiopurine drugs

Streamlining and translating basic science discoveries into the clinic

Researchers discover gene that plays role in regulating body's immune response to infection

Individuals may react differently to environmental chemicals based upon genetic profile

City of Hope receives $3.7 million from CIRM to develop phase 1 glioblastoma trial

eBook: Using iPSCs models for human disease research and drug discovery eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research