Gene News and Research

Latest Gene News and Research

New clinical practice guideline for using CYP2D6 genotype to guide tamoxifen therapy

An international group of clinicians and scientists representing the Clinical Pharmacogenetics Implementation Consortium published the first-ever clinical practice guideline for using CYP2D6 genotype to guide tamoxifen therapy in Clinical Pharmacology and Therapeutics.

1 Feb 2018

Study unravels developmental splicing program that promotes neuronal maturation

Neurons, or nerve cells, in the brain communicate with each other by transmitting electric signals, or firing action potentials, through long processes named axons (which send out signals) and dendrites (which receive signals).

1 Feb 2018

Two bacterial species collaborate to drive development of colon cancers

Patients with an inherited form of colon cancer harbor two bacterial species that collaborate to encourage development of the disease, and the same species have been found in people who develop a sporadic form of colon cancer, a study led by a Johns Hopkins Bloomberg~Kimmel Institute for Cancer Immunotherapy research team finds.

1 Feb 2018

Study identifies new potential target for treatment of blood disorders

UCLA researchers, in collaboration with the University of Iowa, discovered the contribution of a specific gene in the proper development of blood cells that give rise to hematopoietic stem cells.

1 Feb 2018

Exploring the Future of Breast Cancer Risk Assessment

An interview with Dr Gareth Evans about the future of breast cancer screening and the implementation of single nucleotide polymorphism (SNP) profiling.

1 Feb 2018

Scientists discover the genetic cause of immune disorders

Scientists from the Cincinnati Children’s have successfully identified a gene mutation that affects T cell function and promotes immune disorders.

1 Feb 2018

Researchers develop gene therapy for idiopathic pulmonary fibrosis

Researchers have successfully identified the genetic cause of idiopathic pulmonary fibrosis and have shown success in trials of a new gene therapy.

1 Feb 2018

Houston Methodist researchers have new explanation for why airways close during asthma attacks

Houston Methodist researchers have a new explanation for what causes the lungs' airways to close during asthma attacks.

31 Jan 2018

Steven R. Brant shines light on genetic causes for IBD

Whether he is sailboat racing on the Chesapeake Bay or researching genetic causes for inflammatory bowel disease, Steven R. Brant values one quality above all others: a strong team.

31 Jan 2018

Scientists discover role of two specific HOX genes in colon cancer development

In breakthrough colon cancer research, scientists at Christiana Care Health System's Center for Translational Cancer Research of the Helen F. Graham Cancer Center & Research Institute have discovered that over-expression of HOXA4 and HOXA9 genes in colon cancer stem cells promotes cell replication and contributes to the overpopulation of stem cells that drives colon cancer development.

31 Jan 2018

Research reveals why patients with diabetes have poorer prognosis for prostate cancer

Men with type 2 diabetes are less likely to develop prostate cancer than patients without diabetes. However, the mortality rate is higher.

31 Jan 2018

Small molecule plays huge role in keeping people safe from machinations of cancer

One small molecule that helps regulate gene expression plays a big role in keeping us safe from the machinations of cancer, scientists report.

31 Jan 2018

Stealth gene shuttles open up new avenues to treat aggressive cancers

Viruses have their own genetic material and can infect human cells in a very specific manner. They will then reproduce as directed by their own genes but using the resources of the host cell.

31 Jan 2018

Researchers uncover small molecule that plays key role in protecting against cancer

In a new study, researchers have shown that a small molecule involved in the regulation of gene expression plays an important role in protecting against cancer.

31 Jan 2018

Long-term intake of sunflower, fish oils affects the liver

An international group of scientists led by the University of Granada (UGR) has demonstrated that the long-term intake of sunflower or fish oils damages the liver and can cause a series of alterations in it, giving rise to non-alcoholic steatohepatitis.

31 Jan 2018

Researchers take first step in generating artificial adrenal gland

In a new study, published in Cell Reports, researchers from the William Harvey Research Institute at Queen Mary University of London used cells derived from urine to take the first step in generating an artificial adrenal gland.

30 Jan 2018

Study paves new way for development of vaccines against epidemics

The search for vaccines, treatments and preventive methods against infection by emerging viruses is one of the major challenges of global epidemiology.

30 Jan 2018

Expert panel releases updated guidelines for lung cancer molecular testing

Lung cancer treatment often pairs targeted therapies with genetic alterations driving the disease. This makes detecting these genetic alterations an essential step in diagnosis.

30 Jan 2018

Researchers use gene therapy that lengthens telomeres to cure pulmonary fibrosis in mice

Idiopathic pulmonary fibrosis is a potentially lethal disease associated with the presence of critically short telomeres, currently lacking effective treatment.

30 Jan 2018

Scientists discover how gene mutation affects T cell function to promote immune disorders

Scientists discovered how a gene mutation affects T cell function to promote immune disorders and then tested a treatment based on the discovery - successfully fixing donated immune cells from a 16-year-old boy with an abnormally low level of white blood cells called lymphopenia.

30 Jan 2018

Gene News and Research

Latest Gene News and Research

New clinical practice guideline for using CYP2D6 genotype to guide tamoxifen therapy

Study unravels developmental splicing program that promotes neuronal maturation

Two bacterial species collaborate to drive development of colon cancers

Study identifies new potential target for treatment of blood disorders

Exploring the Future of Breast Cancer Risk Assessment

Scientists discover the genetic cause of immune disorders

Researchers develop gene therapy for idiopathic pulmonary fibrosis

Houston Methodist researchers have new explanation for why airways close during asthma attacks

Steven R. Brant shines light on genetic causes for IBD

Scientists discover role of two specific HOX genes in colon cancer development

Research reveals why patients with diabetes have poorer prognosis for prostate cancer

Small molecule plays huge role in keeping people safe from machinations of cancer

Stealth gene shuttles open up new avenues to treat aggressive cancers

Researchers uncover small molecule that plays key role in protecting against cancer

Long-term intake of sunflower, fish oils affects the liver

Researchers take first step in generating artificial adrenal gland

Study paves new way for development of vaccines against epidemics

Expert panel releases updated guidelines for lung cancer molecular testing

Researchers use gene therapy that lengthens telomeres to cure pulmonary fibrosis in mice

Scientists discover how gene mutation affects T cell function to promote immune disorders

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging