Gene News and Research

Latest Gene News and Research

Researchers discover link between rheumatoid arthritis and bacteria in milk

A strain of bacteria commonly found in milk and beef may be a trigger for developing rheumatoid arthritis in people who are genetically at risk, according to a new study from the University of Central Florida.

30 Jan 2018

Study provides novel insights into evolutionary pathways of pancreatic cancer

Pancreatic cancer is a form of cancer associated with the highest mortality rates in the world. Genetic changes that could explain his aggressiveness and early metastasis had not been found yet.

30 Jan 2018

Researchers describe severe toxicity with AAV9-based high-dose gene therapy in animal models

Researchers have described severe, life-threatening toxicity in monkeys and piglets given high doses of gene therapy delivered using an adeno-associated virus (AAV9) vector capable of accessing spinal cord neurons.

30 Jan 2018

Computational approach can help identify chemoresistant potential targets in cancer stem cells

In cancer, one of the most important features is the methylation of deoxycytosine to form 5-methylcytosine (5mC). DNA methylation is a process by which methyl groups (structural units of organic compounds consisting of three hydrogen atoms bonded to a carbon atom) are added to the DNA molecule.

30 Jan 2018

Muscles possess 'memory' of earlier growth at the DNA level, study shows

A study led by researchers at Keele University has shown for the first time that human muscles possess a 'memory' of earlier growth - at the DNA level.

30 Jan 2018

Study lays groundwork for using PD-1 inhibitors against aggressive form of pediatric brain cancer

One type of immunotherapy removes a genetic blindfold that cancer uses to hide from the immune system. These "PD-1 inhibitors", including drugs like pembrolizumab, nivolumab and atezolizumab, have proven useful and have even in some cases revolutionized the treatment of common adult cancers ranging from melanoma, to lung cancer, to kidney cancer and more.

30 Jan 2018

The effects of Huntington’s disease can be seen as early as conception, finds new study

In a breakthrough study, scientists at the Rockefeller University have observed the effects of Huntington’s disease in neurons as early as conception.

30 Jan 2018

Researchers reverse symptoms associated with Rett syndrome in mouse model

It is a parent's nightmare: a child is born apparently healthy, then stops meeting developmental milestones at one year old. Her verbal and motor skills vanish, and irregular breathing, seizures, and a host of other problems appear.

29 Jan 2018

Role of genetics behind immune disease risk could be missed, scientists suggest

The role of genetics in the risk of having an immune disease could be missed in research, scientists suggest.

29 Jan 2018

Groundbreaking study broadens spectrum of cryopyrin-associated periodic syndromes

A research team from the University of Helsinki, Helsinki University Hospital and Folkhälsan Institute of Genetics in Helsinki, Finland, have identified a new genetic mutation that alters the function of cryopyrin and leads to a life-long periodic inflammation of the cornea, the transparent window of the human eye. Patients who carry the mutation also develop corneal opacities that compromise vision.

29 Jan 2018

Rockefeller scientists develop system to model Huntington’s in human embryonic stem cells

With new findings, scientists may be poised to break a long impasse in research on Huntington's disease, a fatal hereditary disorder for which there is currently no treatment.

29 Jan 2018

Enhanced lifestyle counselling could protect against Alzheimer’s disease, finds new study

Enhanced lifestyle counselling could prevent cognitive decline in people who are genetically predisposed to develop Alzheimer’s disease, finds new study.

29 Jan 2018

New study sheds light on important protein involved in memory formation

A team of researchers have made important discoveries about a protein called AKT that is key to the formation of new memories.

29 Jan 2018

Viral replication process weak spot may help develop cure for infections

Researchers at the Morgridge Institute for Research believe they have identified a weak spot in the replication process of positive-strand RNA viruses, which could yield treatment for viral infections such as Zika, Polio, Chikungunya, Hepatitis C and even common cold viruses.

29 Jan 2018

Researchers reveal important role of estrogen in neuroblastoma

The female sex hormone estrogen can perform an important role in neuroblastoma, a form of cancer mainly affecting young children.

29 Jan 2018

Leiden researcher makes new breakthrough in nanotherapy

Nanoparticles that transport medicines to a specific part of the human body are usually broken down in the liver prematurely. Jeroen Bussmann from Leiden University has discovered a new method to prevent this from happening. Publication in ACS Nano.

29 Jan 2018

Scientists decipher molecular mechanism of the cell with relevance for cancer development

Achievement in the field of cancer research: Biologists and chemists at the University of Konstanz decipher a molecular mechanism of the cell with relevance for the development of cancer and the fight against that disease.

27 Jan 2018

Discovery may offer new therapeutic approach for kids with Prader-Willi syndrome

Stem cell researchers at UConn Health have reversed Prader-Willi syndrome in brain cells growing in the lab, findings they recently published in the Human Molecular Genetics.

27 Jan 2018

Small tweak to mammal's DNA can cause significant physical changes, study finds

The difference between webbed toes and distinct digits may be the result of not just genetic information, but of how the genes regulate that information. Researchers at the National Institute of Genetics, Research Organization of Information and Systems in Japan found that a small, non-specific tweak to a mammal's DNA can potentially cause specific and significant physical changes.

27 Jan 2018

Researchers uncover key protein that rescues progression of adult spinocerebellar ataxia

Spinocerebellar ataxia is a group of neurodegenerative diseases characterized by progressive incoordination of gait, and is often associated with poor coordination of hands, speech, and eye movements.

27 Jan 2018

Gene News and Research

Latest Gene News and Research

Researchers discover link between rheumatoid arthritis and bacteria in milk

Study provides novel insights into evolutionary pathways of pancreatic cancer

Researchers describe severe toxicity with AAV9-based high-dose gene therapy in animal models

Computational approach can help identify chemoresistant potential targets in cancer stem cells

Muscles possess 'memory' of earlier growth at the DNA level, study shows

Study lays groundwork for using PD-1 inhibitors against aggressive form of pediatric brain cancer

The effects of Huntington’s disease can be seen as early as conception, finds new study

Researchers reverse symptoms associated with Rett syndrome in mouse model

Role of genetics behind immune disease risk could be missed, scientists suggest

Groundbreaking study broadens spectrum of cryopyrin-associated periodic syndromes

Rockefeller scientists develop system to model Huntington’s in human embryonic stem cells

Enhanced lifestyle counselling could protect against Alzheimer’s disease, finds new study

New study sheds light on important protein involved in memory formation

Viral replication process weak spot may help develop cure for infections

Researchers reveal important role of estrogen in neuroblastoma

Leiden researcher makes new breakthrough in nanotherapy

Scientists decipher molecular mechanism of the cell with relevance for cancer development

Discovery may offer new therapeutic approach for kids with Prader-Willi syndrome

Small tweak to mammal's DNA can cause significant physical changes, study finds

Researchers uncover key protein that rescues progression of adult spinocerebellar ataxia

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Real-time Raman monitoring for pharmaceutical hot melt extrusion

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