Gene News and Research

Latest Gene News and Research

Family study looks at potential genetic distinctions between bipolar disorder subtypes

The most common subtypes of bipolar disorder, bipolar I and bipolar II, stem-at least in part-from different biological causes, according to a new study published in Biological Psychiatry.

10 Jan 2018

New discovery could help treat breast cancer through precision medicine

University of Alberta researchers have discovered a mechanism that may make cancer cells more susceptible to treatment. The research team found that the protein RYBP prevents DNA repair in cancer cells, including breast cancer.

9 Jan 2018

UC scientists identify protein that acts as mediator of HER2-driven breast cancer

Researchers at the University of Cincinnati College of Medicine have identified for the first time that the estrogen receptor-binding protein MED1 is a critical mediator of HER2-driven breast cancer, identifying it as a potential therapeutic target.

9 Jan 2018

New blood stabilization method prolongs lifespan of blood samples for CTC profiling

A new blood stabilization method, developed at the Massachusetts General Hospital Center for Engineering in Medicine, significantly prolongs the lifespan of blood samples for microfluidic sorting and transcriptome profiling of rare circulating tumor cells (CTCs), living cancer cells carried in the bloodstream.

9 Jan 2018

Scientists find gene that predisposes Greenlanders to obesity

Greenland is like many other countries struggling with overweight and obesity. Both environment and genetics play a role in development of obesity.

9 Jan 2018

Scientists uncover how good bacteria regulate genes

Scientists from the Babraham Institute near Cambridge in collaboration with colleagues from Brazil (here and here) and Italy have discovered a way that good bacteria in the gut can control genes in our cells.

9 Jan 2018

Researchers discover why exercise is good and high blood pressure is bad for the heart

When the heart is put under stress during exercise, it is considered healthy. Yet stress due to high blood pressure is bad for the heart. Why? And is this always the case? Researchers of the German Centre for Cardiovascular Research and of Heidelberg University Hospital have obtained new findings which indicate that a previously undetected signal pathway causes or protects from heart failure - depending on the type of stress.

9 Jan 2018

Regeneron forms consortium to accelerate largest widely-available human sequencing resource

By the end of 2019, Regeneron plans to sequence the exomes of all 500,000 people within the UK Biobank resource, all with associated health records, creating an unprecedented resource linking human genetic variations to human biology and disease.

9 Jan 2018

Variations in singular genes could have large impact on hereditary facial features

Do you have your grandmother's eyes? Or your father's nose? A new study by the Universities of Oxford and Surrey has uncovered variations in singular genes that have a large impact on human facial features, paving the way to understanding what determines the facial characteristics passed on from generation to generation.

9 Jan 2018

Leukemia patients currently ineligible for targeted therapy may benefit from new drugs

Patients with an aggressive form of leukemia, currently ineligible for any type of targeted therapy, may in fact benefit from some of these new drugs, according to new research by Queen Mary University of London.

9 Jan 2018

Common gene test to predict breast cancer recurrence may not be cost-effective

The most commonly used gene expression profile test used to help predict breast cancer recurrence may not be as cost-effective as once thought, say a team of researchers led by Georgetown Lombardi Comprehensive Cancer Center.

9 Jan 2018

Researchers discover mutations in a gene related to obesity

Researchers have discovered mutations in a gene related to obesity, offering new treatment possibilities in the fight against the global epidemic.

8 Jan 2018

Study finds a cellular mechanism that protects plant genes from impacts of mutation

According to a new study conducted at the University of Oxford, a cellular mechanism termed DNA mismatch repair (MMR), preferentially protects plant genes from the damaging impacts of mutation.

8 Jan 2018

Polygenic risk score predicts early-onset heart disease risk

A risk score based on multiple genetic differences, or polygenic risk score, predicted significantly more cases of early-onset heart disease than standard tests for single genetic defects, according to new research in the American Heart Association's journal Circulation: Genomic and Precision Medicine.

8 Jan 2018

Sangamo and Pfizer partner for development of new zinc finger protein gene therapy to treat ALS

Sangamo Therapeutics, Inc. and Pfizer Inc. today announced a collaboration for the development of a potential gene therapy using zinc finger protein transcription factors (ZFP-TFs) to treat amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) linked to mutations of the C9ORF72 gene.

8 Jan 2018

New understanding of how molecules regulate enzyme could lead to potential cancer targets

New understandings of how molecules affect the activity of an enzyme could lead to potential targets for the treatment of cancers and neurodegenerative diseases.

5 Jan 2018

Bielefeld scientists discover cause of initially unclear symptoms

The sequencing of the human genome has made it possible: nowadays scientists can discover potential disorders for which there are no known patients.

5 Jan 2018

University of Montana researchers make discovery on unusual gene evolution in bacteria

University of Montana researchers have made another discovery at the cellular level to help understand the basic processes of all life on our planet - this time within the unusual bacteria that has lived inside cicada insects since dinosaurs roamed Earth.

5 Jan 2018

Newly described super-silenced DNA reveals novel approach to reprogram cells

Newly described stretches of super-silenced DNA reveal a fresh approach to reprogram cell identity to use in regenerative medicine studies and one day in the clinic, according to a study in Molecular Cell last week by investigators from the Perelman School of Medicine at the University of Pennsylvania.

5 Jan 2018

Genetic differences can influence efficiency of medicines

Medicines do not follow the one size fits all principle, because genetic differences can influence their efficiency.

5 Jan 2018

Gene News and Research

Latest Gene News and Research

Family study looks at potential genetic distinctions between bipolar disorder subtypes

New discovery could help treat breast cancer through precision medicine

UC scientists identify protein that acts as mediator of HER2-driven breast cancer

New blood stabilization method prolongs lifespan of blood samples for CTC profiling

Scientists find gene that predisposes Greenlanders to obesity

Scientists uncover how good bacteria regulate genes

Researchers discover why exercise is good and high blood pressure is bad for the heart

Regeneron forms consortium to accelerate largest widely-available human sequencing resource

Variations in singular genes could have large impact on hereditary facial features

Leukemia patients currently ineligible for targeted therapy may benefit from new drugs

Common gene test to predict breast cancer recurrence may not be cost-effective

Researchers discover mutations in a gene related to obesity

Study finds a cellular mechanism that protects plant genes from impacts of mutation

Polygenic risk score predicts early-onset heart disease risk

Sangamo and Pfizer partner for development of new zinc finger protein gene therapy to treat ALS

New understanding of how molecules regulate enzyme could lead to potential cancer targets

Bielefeld scientists discover cause of initially unclear symptoms

University of Montana researchers make discovery on unusual gene evolution in bacteria

Newly described super-silenced DNA reveals novel approach to reprogram cells

Genetic differences can influence efficiency of medicines

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