Gene News and Research

Latest Gene News and Research

Researchers reveal potent new mechanism of action for treatment of IBD

Professor Akiyoshi Fukamizu's research group of Life Science Center for Survival Dynamics, University of Tsukuba, Eisai Co., Ltd. and its gastrointestinal business subsidiary EA Pharma Co., Ltd. have revealed a mechanism in which an analogue (ER-464195-01) of Eisai's in-house discovered E6007 inhibits integrin activation by dissociating interaction between calreticulin (CRT) and integrin α 4 (ITGA4), suppressing adhesion and infiltration of leukocytes overall.

25 May 2018

Research suggests link between faulty gene, alcohol, and heart failure

The researchers investigated faulty versions of a gene called titin which are carried by one in 100 people or 600,000 people in the UK.

25 May 2018

Researchers call for new genetic tests for congenital diseases

Researchers have discovered that genetic mutations called epivariations are the cause of certain neurodevelopmental disorders and congenital diseases.

25 May 2018

Researchers identify novel epigenetic mutations as cause of neurodevelopmental, congenital disorders

Researchers have identified a type of genetic aberration to be the cause of certain neurodevelopmental disorders and congenital diseases, such as autism and congenital heart disease, which are undetectable by conventional genetic testing.

25 May 2018

Immune cells promote lung cancer metastases by forming clots in tumors, study finds

University of North Carolina Lineberger Comprehensive Cancer Center researchers have found that by helping to form clots within tumors, immune cells that flock to a particular type of lung cancer are actually building a foundation for the tumor to spread within the body.

25 May 2018

Children and adolescents growing up in extreme societal conditions more likely to resort to violence

Children and adolescents who grow up with one or more of these environmental risk factors are likely to resort to violence, aggression and crime as adults, irrespective of an underlying mental illness.

24 May 2018

Two genes play vital roles in malignant brain cancer

Two genes play important roles for the formation of malignant cancer in the brain. One gene prevents the formation of the tumor, while another gene promotes the tumor. This is shown in a new dissertation at Umeå University, Sweden.

24 May 2018

International researchers succeed in stopping growth of mesothelioma in model animals

An international team led by researchers from the Technion-Israel Institute of Technology and NYU Langone Health have succeeded in stopping the growth of mesothelioma in model animals by inhibiting the heparanase enzyme.

24 May 2018

Study uncovers why pesticide exposure increases Parkinson's disease risk in some people

A new University of Guelph study has discovered why exposure to pesticides increases some people's risk of developing Parkinson's disease.

24 May 2018

Scientists create small, self-contained spaces inside mammalian cells

How to install new capabilities in cells without interfering with their metabolic processes? A team from the Technical University of Munich and the Helmholtz Zentrum München have altered mammalian cells in such a way that they formed artificial compartments in which sequestered reactions could take place, allowing the detection of cells deep in the tissue and also their manipulation with magnetic fields.

23 May 2018

Small part of cellular protein that helps form long-term memories also drives neurodegeneration

Scientists have just discovered that a small region of a cellular protein that helps long-term memories form also drives the neurodegeneration seen in Amyotrophic Lateral Sclerosis (ALS). This small part of the Ataxin-2 protein thus works for good and for bad.

23 May 2018

Study provides blueprint of how fruit flies can be used to screen potentially pathogenic human genes

It all began with one young patient; a 7-year old boy who was born without a thymus, an important organ of the immune system, and without functional immune cells. The boy also presented with cardiac and skeletal defects, dysmorphic craniofacial features and some signs of autistic behaviors.

23 May 2018

HU researchers explore how simulated microgravity affects gene expression, muscle cell differentiation

Astronauts go through many physiological changes during their time in spaceflight, including lower muscle mass and slower muscle development. Similar symptoms can occur in the muscles of people on Earth's surface, too. In fact, it could affect everyone to some extent later in life.

23 May 2018

Mapping the Genes Responsible for Pluripotency

Dr. Atilgan Yilmaz and his team have developed a method by which they can produce haploid human embryonic stem cells from oocytes. They combined this technique with CRISPR-Cas9 to generate an atlas of the genome, containing the functions of over 18,000 genes.

23 May 2018

Scientists identify new inherited neurodevelopmental disease

Researchers have identified a new inherited neurodevelopmental disease that causes slow growth, seizures and learning difficulties in humans.

23 May 2018

Researchers identify mechanisms that regulate mammary gland development

Publication in Nature Cell Biology: researchers at the Université libre de Bruxelles, ULB define for the first time the mechanisms responsible for the mammary gland development.

23 May 2018

Advanced genetics study of TB bacteria uncovers virulent 'Beijing lineage' strain among young adults

LSTM's Dr Maxine Caws is co-lead investigator on an advanced genetics study published in Nature Genetics(link is external), which has shown that a virulent strain of tuberculosis (TB) has adapted to transmit among young adults in Ho Chi Minh City, Vietnam.

23 May 2018

Researchers discover link between tuberculosis and Parkinson's disease

The mechanism our immune cells use to clear bacterial infections like tuberculosis (TB) might also be implicated in Parkinson's disease, according to a new collaborative study led by the Francis Crick Institute, Newcastle University and GSK.

22 May 2018

Research team uncovers new information that more accurately explains formation of tumors

A collaborative research team has uncovered new information that more accurately explains how cancerous tumors grow within the body.

22 May 2018

Researchers discover unexpected chemosensor pathway for predator odor-evoked innate fear behaviors

Innate fear is an essential emotion for animals to avoid danger in a severe natural environment. Rodents kept in a laboratory also show instinctive fear behavior against the smell of predators such as foxes, cats or snakes despite having never seen them.

22 May 2018

Gene News and Research

Latest Gene News and Research

Researchers reveal potent new mechanism of action for treatment of IBD

Research suggests link between faulty gene, alcohol, and heart failure

Researchers call for new genetic tests for congenital diseases

Researchers identify novel epigenetic mutations as cause of neurodevelopmental, congenital disorders

Immune cells promote lung cancer metastases by forming clots in tumors, study finds

Children and adolescents growing up in extreme societal conditions more likely to resort to violence

Two genes play vital roles in malignant brain cancer

International researchers succeed in stopping growth of mesothelioma in model animals

Study uncovers why pesticide exposure increases Parkinson's disease risk in some people

Scientists create small, self-contained spaces inside mammalian cells

Small part of cellular protein that helps form long-term memories also drives neurodegeneration

Study provides blueprint of how fruit flies can be used to screen potentially pathogenic human genes

HU researchers explore how simulated microgravity affects gene expression, muscle cell differentiation

Mapping the Genes Responsible for Pluripotency

Scientists identify new inherited neurodevelopmental disease

Researchers identify mechanisms that regulate mammary gland development

Advanced genetics study of TB bacteria uncovers virulent 'Beijing lineage' strain among young adults

Researchers discover link between tuberculosis and Parkinson's disease

Research team uncovers new information that more accurately explains formation of tumors

Researchers discover unexpected chemosensor pathway for predator odor-evoked innate fear behaviors

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research