Gene News and Research

Latest Gene News and Research

Genetic link to insomnia found

A new study has found certain genes that predispose a person to develop insomnia or sleep problems. This was one of the largest genome wide studies undertaken on insomnia. The study led by psychiatrist Murray Stein from the University of California San Diego was published in the latest issue of the journal Molecular Psychiatry.

13 Mar 2018

Continuous tracking of melanoma cell invasion helps scientists explain key regulators of metastasis

A team of Italian scientists reported this week that blocking the interaction between urokinase receptor (uPAR) and formyl peptide receptor type 1 (FPR1) suppresses the ability of melanoma cells to migrate, invade through an extracellular matrix, and to burrow through a layer of endothelial cells.

13 Mar 2018

Novel oncolytic virus expressing BiTE molecule elicits T cell-mediated killing of tumor cells

In a research article published in EMBO Molecular Medicine, a group of scientists at the University of Oxford have described a new twist on cancer immunotherapy, combining two independent cell killing approaches in a single therapeutic with high potency and broad applicability.

13 Mar 2018

Precision oncology may improve overall survival, lower healthcare costs for advanced cancer patients

The use of advanced molecular diagnostic technologies, such as Next-Generation Sequencing-based gene panel testing, to select targeted therapies in advanced cancer patients is known as precision oncology.

13 Mar 2018

Study identifies two new biomarkers for common form of childhood cancer

Two new biomarkers for a type of cancer in children called neuroblastoma have been identified in a study published in the journal Cancer Cell. The findings are expected to have immediate significance for disease prognosis, and eventually also for treatment.

13 Mar 2018

International research consortium identifies 22 new genetic risk factors for stroke

An international research consortium studying 520,000 individuals from around the world has identified 22 new genetic risk factors for stroke, thus tripling the number of gene regions known to affect stroke risk.

13 Mar 2018

Scientists link 110 genes to increased risk of breast cancer

Scientists have linked 110 genes to an increased risk of breast cancer in the most comprehensive study ever to unpick the genetics of the disease.

13 Mar 2018

Study identifies gene that influences risk of obesity in adulthood

The importance of good nutrition in the early development of children has been recognized for many decades. Nutritional experiences in early life can have profound and long-lasting effects on body weight in later life.

13 Mar 2018

Study highlights potential of ASO therapy to treat Fuchs endothelial corneal dystrophy patients

A proof-of-concept study carried out at UCL Institute of Ophthalmology with funding from Fight for Sight has highlighted the potential of a targeted antisense oligonucleotide therapy to treat Fuchs endothelial corneal dystrophy patients with a mutation in the TCF4 gene.

12 Mar 2018

Researchers develop new method to increase life span of donated brain tissue samples

Researchers at Lund University in Sweden have developed a method that enables them to use donated brain tissue from people with epilepsy for 48 hours. Previously, the researchers only had 12 hours to test new treatments before the structure of the cells started to break down. The research has now been published in the journal Scientific Reports.

9 Mar 2018

Researchers show role for predictive biomarker in neonatal chronic lung disease pathogenesis

Extremely low birth-weight babies are at risk for a chronic lung disease called bronchopulmonary dysplasia, or BPD.

9 Mar 2018

Novel screening tool aids search for curative kidney treatment

Researchers have developed a screening tool for identifying compounds that restore functionality of the protein that is dysfunctional in Alport syndrome.

9 Mar 2018

Modifying Oncolytic Adenoviruses to Target Pancreatic Cancer

Pancreatic cancer is one of the less common but deadliest cancers. Modified oncolytic adenoviruses represent an alternative to chemotherapy and targeted therapies, which have a high mortality rate.

9 Mar 2018

Scientists uncover detailed map of the brain circuits behind thirst and satiety

Scientists uncovered a high-resolution map of the wiring inside the mouse brain's thirst center. With these blueprints, they could trick mice into becoming light or heavy water drinkers.

8 Mar 2018

Study sheds light on earliest stages in evolution of male-female sexes

A new study published in the journal Communications Biology has shed light on the earliest stages in the evolution of male-female differentiation and sex chromosomes--and found the genetic origins of the two sexes to be unexpectedly modest.

8 Mar 2018

Study seeks to examine whether gut bacteria cause brain dysfunction in sepsis patients

Surviving a critical illness is no small feat, but it's only half the battle for many patients. Serious complications can still result after an illness appears to have cleared.

8 Mar 2018

Newly-discovered hereditary mutation leads to increased production of EPO in the blood

A newly-discovered hereditary mutation is responsible for an increased production of erythropoietin (EPO) in the blood.

8 Mar 2018

Study reveals key function of ALS-linked protein

The protein FUS, whose mutation or disruption causes many cases of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), works as a central component of one of the most important regulatory systems in cells, according to a new study in Molecular Cell from scientists at Johns Hopkins Bloomberg School of Public Health.

8 Mar 2018

Boosting the brain's immune cells may prevent or reduce severity of Alzheimer's disease

Sanford Burnham Prebys Medical Research Institute researchers have published two new studies in Neuron that describe how TREM2, a receptor found on immune cells in the brain, interacts with toxic amyloid beta proteins to restore neurological function.

8 Mar 2018

Research reveals neuroprotective mechanisms of gene and cell medications for spinal cord injuries

A joint paper with Kazan State Medical University appeared in Stem Cells International. The research was based at the Gene and Cell Technologies Lab of Kazan University.

8 Mar 2018

Gene News and Research

Latest Gene News and Research

Genetic link to insomnia found

Continuous tracking of melanoma cell invasion helps scientists explain key regulators of metastasis

Novel oncolytic virus expressing BiTE molecule elicits T cell-mediated killing of tumor cells

Precision oncology may improve overall survival, lower healthcare costs for advanced cancer patients

Study identifies two new biomarkers for common form of childhood cancer

International research consortium identifies 22 new genetic risk factors for stroke

Scientists link 110 genes to increased risk of breast cancer

Study identifies gene that influences risk of obesity in adulthood

Study highlights potential of ASO therapy to treat Fuchs endothelial corneal dystrophy patients

Researchers develop new method to increase life span of donated brain tissue samples

Researchers show role for predictive biomarker in neonatal chronic lung disease pathogenesis

Novel screening tool aids search for curative kidney treatment

Modifying Oncolytic Adenoviruses to Target Pancreatic Cancer

Scientists uncover detailed map of the brain circuits behind thirst and satiety

Study sheds light on earliest stages in evolution of male-female sexes

Study seeks to examine whether gut bacteria cause brain dysfunction in sepsis patients

Newly-discovered hereditary mutation leads to increased production of EPO in the blood

Study reveals key function of ALS-linked protein

Boosting the brain's immune cells may prevent or reduce severity of Alzheimer's disease

Research reveals neuroprotective mechanisms of gene and cell medications for spinal cord injuries

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research