Gene News and Research

Latest Gene News and Research

New therapeutic strategy exploits acquired vulnerability in drug-resistant cancer

Cancer cells that develop resistance to drugs, pay a price for this, by simultaneously developing a new vulnerability. If this acquired vulnerability can be identified, it may be exploited clinically.

10 May 2018

Study finds way to better treat men with locally advanced prostate cancer

A new study published today has found a way to identify men with locally advanced prostate cancer who are less likely to respond well to radiotherapy.

10 May 2018

Enhancing the effects of vitamin D to curb type 2 diabetes

More than 27 million people in the United States are living with type 2 diabetes, according to the Centers for Disease Control and Prevention. As the population ages and a growing percentage of people become overweight or obese, that number is expected to increase.

10 May 2018

Researchers discover genetic signal common to cerebral palsy and autism

University of Adelaide researchers have uncovered a genetic signal common to both cerebral palsy and autism.

10 May 2018

Study reveals the genetics underlying cerebral palsy and autism

Researchers from the Robinson Research Institute at the University of Adelaide have uncovered a genetic signal that is common to both cerebral palsy and autism.

10 May 2018

Phase 2 study of dexpramipexole in hypereosinophilic syndromes meets its co-primary endpoints

Knopp Biosciences LLC today announced the publication of a report in the journal Blood that a Phase 2 study of dexpramipexole in hypereosinophilic syndromes met its co-primary endpoints.

10 May 2018

Scientists identify mutation that makes tumor cells resistant to breast and ovarian cancer drug

Scientists have identified a mutation that gives cancer cells resistance to the breakthrough cancer treatment olaparib and other PARP inhibitors.

10 May 2018

Study discovers genetic variations that increase heart attack risk for statin patients

A Vanderbilt-led research team has discovered genetic variations that increase the risk of heart attack even when patients are receiving a statin drug like Lipitor or Crestor to lower their blood cholesterol.

10 May 2018

Researchers identify six genes that predispose carriers to develop medulloblastoma

Researchers have identified six genes that predispose carriers to develop the brain tumor medulloblastoma and have used the discovery to craft genetic counseling and screening guidelines. The study appears today in the journal The Lancet Oncology.

10 May 2018

New case study shows CAR T therapy as viable option for AML patients

Chimeric Antigen Receptor T-cell therapy, also known as CAR T therapy, was named the biggest research breakthrough of 2017 by the American Society of Clinical Oncology. The personal gene therapy utilizes a patient's own immune cells to fight cancer.

9 May 2018

International research collaboration aims to prevent heart arrhythmias with gene therapy

The most common and potentially lethal complication following a heart attack is the heart's inability to do one of its most basic jobs: beat at a normal rate.

9 May 2018

Advances in Cell Lineage Analysis

Dr. Jan Phillip Junker discusses the applications of CRISPR-Cas9 in cell lineage analysis and the development of tomo-seq; a method to study the spatial organization of cells within whole organisms.

9 May 2018

Disruption of the body's circadian rhythm linked to increased risk of breast cancer

For years, doctors have associated the BRCA1 and BRCA2 gene mutations with an increased risk of breast cancer.

9 May 2018

Scientists develop computer algorithm that reveals gene networks activated in cancer cell

Recent headlines have cast suspicion on social network analysis, which can mine data from the internet to target advertisements or potentially influence elections.

9 May 2018

ONC201 disrupts mitochondrial function and kills breast cancer cells, reveals study

TRAIL, a member of the TNF family of ligands, causes caspase-dependent apoptosis through activation of its receptors, death receptor 4 and DR5.

9 May 2018

Findings confirm analytical principle that describes mutational processes and cancer development

When a cell develops into a tumor, something has gone terribly wrong: the uncontrolled growth, invasion of nearby tissues and finally metastasis are the result of many consecutive DNA mutations.

9 May 2018

Researchers uncover the cause of scarring in idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is one of the most challenging and frustrating diseases that pulmonologists face.

9 May 2018

Allen Institute for Cell Science launches first predictive and comprehensive, 3D model of live human cell

The Allen Institute for Cell Science today launched the first predictive and comprehensive, 3D model of a live human cell, the Allen Integrated Cell.

9 May 2018

New findings point to potential therapeutic avenues for leukemia

Scientists have known for decades that the Hox family of transcription factors are key regulators in the formation of blood cells and the development of leukemia.

9 May 2018

Centrosome amplification may contribute to initiation of cancers, research suggests

Cells begin to accumulate centrosomes - organelles that play a vital role during cell division - before they transform into cancer cells, according to a new study of patients with Barrett's esophagus condition, which is associated with esophageal cancer.

8 May 2018

Gene News and Research

Latest Gene News and Research

New therapeutic strategy exploits acquired vulnerability in drug-resistant cancer

Study finds way to better treat men with locally advanced prostate cancer

Enhancing the effects of vitamin D to curb type 2 diabetes

Researchers discover genetic signal common to cerebral palsy and autism

Study reveals the genetics underlying cerebral palsy and autism

Phase 2 study of dexpramipexole in hypereosinophilic syndromes meets its co-primary endpoints

Scientists identify mutation that makes tumor cells resistant to breast and ovarian cancer drug

Study discovers genetic variations that increase heart attack risk for statin patients

Researchers identify six genes that predispose carriers to develop medulloblastoma

New case study shows CAR T therapy as viable option for AML patients

International research collaboration aims to prevent heart arrhythmias with gene therapy

Advances in Cell Lineage Analysis

Disruption of the body's circadian rhythm linked to increased risk of breast cancer

Scientists develop computer algorithm that reveals gene networks activated in cancer cell

ONC201 disrupts mitochondrial function and kills breast cancer cells, reveals study

Findings confirm analytical principle that describes mutational processes and cancer development

Researchers uncover the cause of scarring in idiopathic pulmonary fibrosis

Allen Institute for Cell Science launches first predictive and comprehensive, 3D model of live human cell

New findings point to potential therapeutic avenues for leukemia

Centrosome amplification may contribute to initiation of cancers, research suggests

eBook: Using iPSCs models for human disease research and drug discovery eBook

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Industry focus eBook: Genomics (4th edition)

Industry Focus eBook - Clinical & Point of Care Diagnostics (1st edition)

Editorial Focus eBook - Peptides and Oligonucleotides (2nd edition)

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

How industrial hygiene flow calibration supports defensible exposure data