Gene News and Research

Latest Gene News and Research

New drug-based treatment to promote weight loss in young patients with genetic obesity

In a new study researchers from the Institute for Experimental Pediatric Endocrinology of the Charité - Universitätsmedizin Berlin have successfully treat patients whose obesity is caused by a genetic defect.

8 May 2018

Alnylam achieves delivery of novel siRNAs conjugates to the central nervous system

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today that the Company has achieved delivery of novel small interfering RNA conjugates to the central nervous system and is planning to advance a pipeline of investigational RNAi therapeutics into clinical development.

8 May 2018

Researchers harness the precision of CRISPR to knock out single genes in yeast

Researchers have used CRISPR-Cas9 to develop a technology that can precisely target any gene in the yeast species Saccharomyces cerevisiae.

8 May 2018

Scientists discover a small family of proteins that control inclusion of DNA methylation marks in genome

Not all of your genome needs to be active at any given time. Some regions are prone to hopping around the genome in problematic ways if left unchecked; others code for genes that need to be turned off in certain cells or at certain times.

8 May 2018

PFKFB3 enzyme appears to play a key role in pulmonary hypertension

A new and early target for treating pulmonary hypertension appears to be an enzyme that's normally key to energy production but destructive in the face of this high blood pressure inside your lungs.

8 May 2018

Using human induced pluripotent stem cells for therapeutic drug testing

Researchers at Li Ka Shing Faculty of Medicine of The University of Hong Kong have successfully demonstrated the use of human induced pluripotent stem cells from patients' skin cells for therapeutic drug testing.

8 May 2018

Night shifts may have negative impact on long-term health

A team of researchers from the McGill University affiliated Douglas Mental Health University Institute (DMHUI) has discovered that genes regulating important biological processes are incapable of adapting to new sleeping and eating patterns and that most of them stay tuned to their daytime biological clock rhythms.

8 May 2018

FDA grants approval for two drugs administered together to treat aggressive form of thyroid cancer

The U.S. Food and Drug Administration approved Tafinlar (dabrafenib) and Mekinist (trametinib), administered together, for the treatment of anaplastic thyroid cancer (ATC) that cannot be removed by surgery or has spread to other parts of the body (metastatic), and has a type of abnormal gene, BRAF V600E (BRAF V600E mutation-positive).

8 May 2018

Study adds robust evidence to higher prevalence of Alzheimer's among women than men

The APOE gene, the strongest genetic risk factor for Alzheimer's disease, may play a more prominent role in disease development among women than men, according to new research from the Vanderbilt Memory and Alzheimer's Center.

8 May 2018

Preclinical study suggests ARID1a mutations may help predict immunotherapy success

Functional loss of ARID1a, a frequently mutated tumor suppressor gene, causes deficiencies in normal DNA repair and may sensitize tumors to immune checkpoint blockade therapies, according to researchers from The University of Texas MD Anderson Cancer Center.

8 May 2018

Nuclear pore complexes are critical for survival of circulating T cells, study shows

Nuclear pore complexes in the nuclear membrane not only control the transport of molecules into and out of the nucleus- they play an essential role in the survival of T cells.

8 May 2018

Cancer scientists confirm oligometastasis hypothesis

In 1995, two University of Chicago-based cancer specialists suggested there was an intermediate state - somewhere between curable localized cancers and lethal widespread disease - for patients with metastatic cancer.

7 May 2018

Scientists shed light on formation of new blood vessels

How new blood vessels form in mammals, for example during development or after injury, was so far not known exactly. Scientists at the Goethe University have now been able to shed light on this process.

7 May 2018

New data supports clinical use of DecisionDx-Melanoma test to inform SLNB options

Castle Biosciences, Inc., the skin cancer diagnostics company providing molecular diagnostics to improve cancer treatment decisions, today announced the presentation of data supporting clinical use of the DecisionDx®-Melanoma test to inform sentinel lymph node biopsy (SLNB) recommendations.

7 May 2018

Gene News and Research

Latest Gene News and Research

New drug-based treatment to promote weight loss in young patients with genetic obesity

Alnylam achieves delivery of novel siRNAs conjugates to the central nervous system

Researchers harness the precision of CRISPR to knock out single genes in yeast

Scientists discover a small family of proteins that control inclusion of DNA methylation marks in genome

PFKFB3 enzyme appears to play a key role in pulmonary hypertension

Using human induced pluripotent stem cells for therapeutic drug testing

Night shifts may have negative impact on long-term health

FDA grants approval for two drugs administered together to treat aggressive form of thyroid cancer

Study adds robust evidence to higher prevalence of Alzheimer's among women than men

Preclinical study suggests ARID1a mutations may help predict immunotherapy success

Nuclear pore complexes are critical for survival of circulating T cells, study shows

Cancer scientists confirm oligometastasis hypothesis

Scientists shed light on formation of new blood vessels

New data supports clinical use of DecisionDx-Melanoma test to inform SLNB options

EPO's neuroprotective effect in preemies may be mediated by epigenetic regulation of genes

Researchers discover how key brain receptor can function in hostile environment

Discovery could be used as starting point for development of new antibiotics

Stimulant use may negatively affect health of HIV-positive persons

Study shows advantages of using decellularized muscle to promote tissue regeneration

New eye drop may be potentially effective in treating seasonal eye allergies

eBook: Using iPSCs models for human disease research and drug discovery eBook

Latest eBooks

Industry Focus eBook - Neurology/Neuroscience - 2nd edition

Industry focus eBook: Genomics (4th edition)

Industry Focus eBook - Clinical & Point of Care Diagnostics (1st edition)

Editorial Focus eBook - Peptides and Oligonucleotides (2nd edition)

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

How industrial hygiene flow calibration supports defensible exposure data