Gene News and Research

Latest Gene News and Research

LMU researchers show how genetic variant in people of African ancestry modulates immune cells

A genetic variant that is particularly prevalent in people of African ancestry confers protection against malaria. LMU researchers have now shown how it modulates the properties of white blood cells that play a major role in immune defenses and inflammation.

1 Jun 2017

Researchers find new way to block type 1 diabetes

Researchers at The Jackson Laboratory, Cyteir Therapeutics and collaborating institutions have found a way to protect beta cells from destruction -- achieving a longtime, elusive goal that could lead to therapies preventing type 1 diabetes (T1D).

1 Jun 2017

New study establishes link between prenatal stress and onset of eating disorders

Stress affects the body and can trigger illness -- from psychiatric disorders to heart disease. Humans are exposed to stress at different intensities throughout life -- as children, in adolescence, and in old age. But when is the impact of stress on our systems most powerful? Many researchers maintain that the critical effect occurs prenatally, inside the womb.

1 Jun 2017

Scientists identify new gene that prompts muscle stem cells to fuse together

A detour on the road to regenerative medicine for people with muscular disorders is figuring out how to coax muscle stem cells to fuse together and form functioning skeletal muscle tissues.

1 Jun 2017

Key metabolic enzyme fuels molecular machinery to turn on memory genes after learning

Understanding how memories are made, retrieved, and eventually fade over a lifetime is the stuff of poems and song. To medical researchers, solving the mysteries of memory is even more elusive.

1 Jun 2017

Micropollutants exert stress on aquatic ecosystems

In Switzerland, more than 30,000 different substances are used on a daily basis in innumerable products - pharmaceuticals, cosmetics, cleaning agents or industrial chemicals.

1 Jun 2017

Single protein allows mycobacteria to generate diverse populations and avoid TB drugs, research shows

Subgroups of tuberculosis (TB)-causing bacteria can persist even when antibiotics wipe out most of the overall population. The need to eliminate these persistent subpopulations is one reason why TB treatment regimens are so lengthy.

1 Jun 2017

Phase 2 clinical study examines Alzheimer's disease drug to treat adults with Down syndrome

A phase 2 clinical trial in young adults with Down syndrome of a drug being investigated for the treatment of Alzheimer's disease supports further investigation of its potential.

1 Jun 2017

Brain's immune cells may play roles in neurodegenerative, psychiatric illnesses

Scientists have, for the first time, characterized the molecular markers that make the brain's front lines of immune defense--cells called microglia--unique.

31 May 2017

Collaborative effort to develop rare disease patient registries

The Orphan Disease Center in the Perelman School of Medicine at the University of Pennsylvania will collaborate with Pulse Infoframe Inc., a medical informatics company, to develop rare disease patient registries aimed at enabling international collaboration to better understand these diseases, as well as accelerate and improve clinical studies to develop new therapies.

31 May 2017

MGH scientists show how Shigella survives journey from mouth to the colon

Surviving the treacherous journey through the human body from the mouth to the colon takes a special kind of bacterial pathogen.

31 May 2017

Moffitt researchers hope to improve personalized radiation therapy for head and neck cancer patients

Radiation therapy is one of the most common treatments used to fight cancer, with an estimated 500,000 people each year receiving radiation therapy either alone or in combination with other treatments.

31 May 2017

Study sheds light on mechanisms that maintain gene activity in embryonic stem cells

Researchers from Turku, Finland, have discovered new information about the mechanisms which maintain gene activity in human embryonic stem cells.

31 May 2017

Cancer treatment may be effective therapy for psoriasis

HDAC inhibitors, already widely used to treat cancer, may be an effective therapy for psoriasis as well, scientists report.

31 May 2017

Combining oral drug with personalized cell therapy can lead to complete remission in CLL patients

Combining the kinase inhibitor ibrutinib with an investigational personalized cellular therapy known as CTL119 can lead to complete remission in patients with high-risk chronic lymphocytic leukemia (CLL), according to new research from the Perelman School of Medicine at the University of Pennsylvania and Penn's Abramson Cancer Center

31 May 2017

TB germs' metabolic 'escape pathways' may be neutralized by new drugs to shorten duration of therapy

New research suggests the bacteria that cause tuberculosis alter their metabolism to combat exposure to antimicrobials, and that these metabolic "escape pathways" might be neutralized by new drugs to shorten the troublesome duration of therapy.

31 May 2017

Researchers make significant advance in treatment of bowel cancer

New research led by Queen's University Belfast has discovered how a genomic approach to understanding bowel (colorectal) cancer could improve the prognosis and quality of life for patients.

31 May 2017

Radboudumc, iMM Lisboa, PATH team up to test new malaria vaccine concept

The Radboud University Medical Center in the Netherlands, the Instituto de Medicina Molecular Lisboa in Portugal, and PATH in Seattle, Washington announced today that they will collaborate to test a new approach to malaria vaccine development in humans for the first time.

31 May 2017

Real-time imaging of influenza infection in mice can be promising evaluation tool

Real-time imaging of influenza infection in mice is a promising new method to quickly monitor disease progression and to evaluate whether candidate vaccines and treatments are effective in this animal model, according to National Institutes of Health scientists.

31 May 2017

GW researcher receives NIH funding to explore ways for standardization of cancer genomics data

One of the biggest challenges facing cancer genomics researchers is the lack normalized data on cancer genes. Multitudes of genomics projects have been funded over the years that have resulted in data being placed on several different databases, making a wide array of data and annotations difficult to integrate and compare.

30 May 2017

Gene News and Research

Latest Gene News and Research

LMU researchers show how genetic variant in people of African ancestry modulates immune cells

Researchers find new way to block type 1 diabetes

New study establishes link between prenatal stress and onset of eating disorders

Scientists identify new gene that prompts muscle stem cells to fuse together

Key metabolic enzyme fuels molecular machinery to turn on memory genes after learning

Micropollutants exert stress on aquatic ecosystems

Single protein allows mycobacteria to generate diverse populations and avoid TB drugs, research shows

Phase 2 clinical study examines Alzheimer's disease drug to treat adults with Down syndrome

Brain's immune cells may play roles in neurodegenerative, psychiatric illnesses

Collaborative effort to develop rare disease patient registries

MGH scientists show how Shigella survives journey from mouth to the colon

Moffitt researchers hope to improve personalized radiation therapy for head and neck cancer patients

Study sheds light on mechanisms that maintain gene activity in embryonic stem cells

Cancer treatment may be effective therapy for psoriasis

Combining oral drug with personalized cell therapy can lead to complete remission in CLL patients

TB germs' metabolic 'escape pathways' may be neutralized by new drugs to shorten duration of therapy

Researchers make significant advance in treatment of bowel cancer

Radboudumc, iMM Lisboa, PATH team up to test new malaria vaccine concept

Real-time imaging of influenza infection in mice can be promising evaluation tool

GW researcher receives NIH funding to explore ways for standardization of cancer genomics data

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