Gene News and Research

Latest Gene News and Research

Alcohol-craving rats offer insights into genetic underpinnings of alcoholism

Alcohol-craving rats have provided researchers with a detailed look into the complicated genetic underpinnings of alcoholism.

5 Aug 2016

Review provides new insights into diagnosis, treatment for PCOS

Polycystic ovary syndrome (PCOS) afflicts over 14 million women in the United States. The disorder increases the risk of endometrial cancer, heart disease, high blood pressure, type 2 diabetes, asthma, obesity, depression and anxiety, as well as infertility and a variety of reproductive disorders.

4 Aug 2016

New study analyzes evolution of epigenetic mechanisms from bacteria to humans

After the emergence of single-celled organisms some billions of years ago, nature started experimenting with how to diversify gene function without changing the sequence of the DNA, such that the blue print remains conserved, but allows gene products to have different functions.

4 Aug 2016

Research shows alcohol abuse drug inhibits ocular conjunctival scarring in mouse model

New research from University College London, Moorfields Eye Hospital and Duke University School of Medicine has identified a gene that drives scarring, together with a rapidly translatable therapy, for the UK's most common cause of blinding conjunctivitis.

4 Aug 2016

Amish farm environment protects children from asthma by shaping immune system

By probing the differences between two farming communities—the Amish of Indiana and the Hutterites of South Dakota—an interdisciplinary team of researchers found that specific aspects of the Amish environment are associated with changes to immune cells that appear to protect children from developing asthma.

4 Aug 2016

Brazilian study discovers promising therapeutic and diagnostic target for treatment of melanoma

A Brazilian study shows that inhibition of an RNA named RMEL3, which is encoded by a previously uncharacterized gene (also named RMEL3), can reduce the viability of cultured melanoma cells by up to 95%.

4 Aug 2016

Sickle cell trait may not increase mortality risk

People who carry a gene for sickle cell disease do not appear to be at an increased risk of premature death, according to a study by researchers from Stanford University School of Medicine.

4 Aug 2016

Research could help develop better therapies for new subtype of adenocarcinoma patients

Lung cancer is the most common cause of cancer deaths, accounting for about a third of all tumor-related deaths. Adenocarcinomas, a non-small cell lung cancer (NSCLC), account for about 40 percent of cancer diagnoses, but few treatments are available for the disease.

4 Aug 2016

New tool helps researchers make connections between proteins, genes, drugs and diseases

Every day, more than 3,000 new abstracts are uploaded to PubMed, the main biomedical literature reference database. Even in a researcher's narrowly-defined field, it is impossible to stay on top of the ever-evolving webs of interconnections between these papers.

4 Aug 2016

Research findings may have implications for ALS and other neurological disorders

Amyotrophic lateral sclerosis (ALS, or Lou Gehrig's disease) is a progressive disorder that devastates motor nerve cells. People diagnosed with ALS slowly lose the ability to control muscle movement, and are ultimately unable to speak, eat, move, or breathe.

4 Aug 2016

Combinations of FDA-approved drugs may prevent vision loss linked to retinal degeneration

Combinations of Food and Drug Administration-approved drugs protect against the loss of cells required for vision in a mouse model of blinding retinal diseases.

4 Aug 2016

NIH launches clinical trial of experimental vaccine candidate for preventing Zika virus infection

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, has launched a clinical trial of a vaccine candidate intended to prevent Zika virus infection.

3 Aug 2016

New biochip test helps identify individuals at increased risk of Alzheimer's disease

Researchers today unveiled results from a new blood test to help identify which patients are at an elevated risk of Alzheimer's disease.

3 Aug 2016

Scientists uncover genetic cause of rare pediatric progressive neuropathy

Researchers from the National Institutes of Health and their colleagues identified the genetic cause and a possible therapeutic target for a rare form of pediatric progressive neuropathy.

3 Aug 2016

Rice University bioengineer receives NIH grant to study use of AAV-based therapy to combat ovarian cancer

Rice University bioengineer Junghae Suh has been awarded a prestigious R01 grant by the National Institutes of Health to research the use of viral gene therapy to fight ovarian cancer.

3 Aug 2016

PD-1-responsive T cells may offer clues to design more effective drugs for cancer

Cancer immunotherapy drugs that block the inhibitory PD-1 pathway have shown success in clinical trials and are now FDA-approved for melanoma, lung cancer and bladder cancer. Yet many patients' tumors do not respond to these drugs.

3 Aug 2016

Scientists engineer therapeutic system with two arms to get better hold on cancer target

Scientists have engineered a sort of biological barbell that can get inside cancer cells and do damage to two proteins that work independently and together to enable cancer's survival and spread.

3 Aug 2016

Lower weight late in life linked to greater risk for Alzheimer's disease

Researchers at Brigham and Women's Hospital and Massachusetts General Hospital have found an association between lower weight and more extensive deposits of the Alzheimer's-associated protein beta-amyloid in the brains of cognitively normal older individuals.

2 Aug 2016

Next-generation sequencing to evaluate cell-free DNA yields more accurate results in diagnosis of MDS

Using next-generation sequencing (NGS) methods to analyze cell-free DNA in the blood of patients with myelodysplastic syndrome (MDS) yields more accurate results than the current standard approach of Sanger sequencing.

2 Aug 2016

Researchers identify crucial innate immunity role for gene linked to ARC syndrome in children

UT Southwestern Medical Center researchers have found an important innate immunity role for a gene linked to a rare, fatal syndrome in children. Their study has implications for a much more common disease: tuberculosis.

2 Aug 2016

Gene News and Research

Latest Gene News and Research

Alcohol-craving rats offer insights into genetic underpinnings of alcoholism

Review provides new insights into diagnosis, treatment for PCOS

New study analyzes evolution of epigenetic mechanisms from bacteria to humans

Research shows alcohol abuse drug inhibits ocular conjunctival scarring in mouse model

Amish farm environment protects children from asthma by shaping immune system

Brazilian study discovers promising therapeutic and diagnostic target for treatment of melanoma

Sickle cell trait may not increase mortality risk

Research could help develop better therapies for new subtype of adenocarcinoma patients

New tool helps researchers make connections between proteins, genes, drugs and diseases

Research findings may have implications for ALS and other neurological disorders

Combinations of FDA-approved drugs may prevent vision loss linked to retinal degeneration

NIH launches clinical trial of experimental vaccine candidate for preventing Zika virus infection

New biochip test helps identify individuals at increased risk of Alzheimer's disease

Scientists uncover genetic cause of rare pediatric progressive neuropathy

Rice University bioengineer receives NIH grant to study use of AAV-based therapy to combat ovarian cancer

PD-1-responsive T cells may offer clues to design more effective drugs for cancer

Scientists engineer therapeutic system with two arms to get better hold on cancer target

Lower weight late in life linked to greater risk for Alzheimer's disease

Next-generation sequencing to evaluate cell-free DNA yields more accurate results in diagnosis of MDS

Researchers identify crucial innate immunity role for gene linked to ARC syndrome in children

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