Gene News and Research

Latest Gene News and Research

Penn researchers identify new immune system mechanism to fight against infections

The innate immune system serves as a first-line defense, responding to infections almost immediately after a pathogen makes its way into the body.

17 Oct 2016

Researchers develop MRI-based method that can track progression of genetically mutated gliomas

UT Southwestern Medical Center researchers have developed an MRI-based method that can track the state and progression of a common type of genetically mutated brain cancer.

17 Oct 2016

Icelandic people more likely to carry novel rare genetic variant linked to risk of Alzheimer's disease

People with Icelandic heritage are more likely to carry a novel rare mutation in the TM2D3 gene, which leads to greater risk for Alzheimer's disease, based on a new study published October 14th, 2016 in PLOS Genetics by Johanna Jakobsdottir of the Icelandic Heart Association, Sven van der Lee of Erasmus University in Rotterdam, and colleagues.

17 Oct 2016

Long-term clinical data, experience supports effectiveness of PRRT for treating neuroendocrine tumors

More than ten years of published clinical data and personal experience using PRRT-based targeted therapy of neuroendocrine tumors supports the effectiveness of this novel treatment approach and the ability to minimize and manage potential toxic side effects.

17 Oct 2016

Research shows how mitochondrial targeting antioxidants could help treat osteoarthritis

High cholesterol might harm more than our cardiovascular systems. New research using animal models, published online in The FASEB Journal, suggests that high cholesterol levels trigger mitochondrial oxidative stress on cartilage cells, causing them to die, and ultimately leading to the development of osteoarthritis.

17 Oct 2016

Immune system plays important role in Duchenne muscular dystrophy, research reveals

A new paper, co-written by faculty at Binghamton University, State University of New York, increases the understanding of Duchenne muscular dystrophy (DMD)—one of the most common lethal genetic disorders—and points to potential therapeutic approaches.

14 Oct 2016

Swedish researchers develop new, low-cost method to examine individual leukemia cells

Leukemia is a disease in which each cell can exhibit different genetic traits, and now Swedish researchers have found a cheap way to examine the individual cells. Reported in Nature Communications, the breakthrough could transform leukemia treatment.

14 Oct 2016

Crohn's disease appears to have two distinct genetic subtypes, study finds

Crohn's disease, a common inflammatory disorder of the intestinal tract, can have devastating consequences for a patient's quality of life and is notoriously hard to treat successfully, in part because its course and severity vary so much from one case to the next.

14 Oct 2016

Study provides insights into how species adapt to changing environments over many generations

Research led by the European Bioinformatics Institute and the University of Washington has shown that the biological diversity needed for evolution can be generated by changes in protein modifications.

14 Oct 2016

Clinical Genomics’ blood test detects twice the number of colorectal cancer recurrence cases than CEA testing

Clinical Genomics, a private company developing innovative diagnostic tools for colorectal cancer, today announced that data supporting its two-gene circulating tumor DNA (ctDNA) blood test for post-surgical monitoring of colorectal cancer (CRC) recurrence have been published online by Cancer Medicine, and will appear in the October issue.

14 Oct 2016

Discovery of neuropilin 2 deficiency may lead to new therapies for edema and lymphedema

Fluid accumulation and swelling (edema) may result from the malfunctioning of regulatory processes controlling vessel permeability in the body.

14 Oct 2016

Researchers develop mouse model to investigate behavioral effects of eating disorder gene

Giving mice a gene mutation linked to eating disorders in people causes feeding and behavior abnormalities similar to symptoms often seen in patients with eating disorders. Only female mice are affected by the gene mutation, and some of the abnormalities in the female mice depend on whether they are housed alone or together with other mice.

13 Oct 2016

Penn researchers receive $5.2 million NIH grant to study mechanisms that promote lung regeneration

Penn Medicine researchers, along with colleagues at Cincinnati Children's Hospital and Boston University, have received a $5.2 million, seven-year grant from the National Heart, Lung, and Blood Institute of the National Institutes of Health to study the cellular and molecular mechanisms that promote lung regeneration.

13 Oct 2016

Wayne State receives NIH funding to develop interventions for better asthma management in youth

A team of researchers led by Richard Slatcher, Ph.D., associate professor of psychology in the College of Liberal Arts and Sciences at Wayne State University, has been awarded $2.74 million from the National Heart, Lung and Blood Institute of the National Institutes of Health for a project that aims to improve asthma management in youth.

13 Oct 2016

OGT announces expansion of Cytocell Aquarius Haematology FISH probe range

Oxford Gene Technology, The Molecular Genetics Company, has today announced a significant expansion of its existing catalogue of Cytocell Aquarius Haematology probes for fluorescence in situ hybridisation (FISH) — underlining the company's position as the one-stop-shop for high-quality FISH probes.

13 Oct 2016

New research reveals key protein involved in heart failure

A key protein that causes heart failure has been revealed through new research from a collaboration based in Kumamoto University, Japan.

13 Oct 2016

New evolutionary analysis provides insights into how Zika virus spreads between populations

In a study published in Pathogens and Global Health, researchers have modelled the evolutionary development and diversity of the Zika virus to better understand how infection spreads between populations and how the virus reacts with the immune system.

13 Oct 2016

High folate intake may increase risk of peripheral neuropathy in older adults with common gene variant

Consuming too much folate (vitamin B9) is associated with increased risk for a nerve-damage disorder in older adults who have a common genetic variant.

12 Oct 2016

Genome engineering-based methods pave way for new treatment of patients with sickle cell disease

A team of physicians and laboratory scientists has taken a key step toward a cure for sickle cell disease, using CRISPR-Cas9 gene editing to fix the mutated gene responsible for the disease in stem cells from the blood of affected patients.

12 Oct 2016

Study identifies mechanistic link between maternal obesity and childhood hypertension

Exposure of babies to high levels of the 'fullness' hormone, leptin, in the womb irreversibly activates receptors in the brain that regulate blood pressure, according to a new study by researchers from King's College London, part-funded by the British Heart Foundation.

12 Oct 2016

Gene News and Research

Latest Gene News and Research

Penn researchers identify new immune system mechanism to fight against infections

Researchers develop MRI-based method that can track progression of genetically mutated gliomas

Icelandic people more likely to carry novel rare genetic variant linked to risk of Alzheimer's disease

Long-term clinical data, experience supports effectiveness of PRRT for treating neuroendocrine tumors

Research shows how mitochondrial targeting antioxidants could help treat osteoarthritis

Immune system plays important role in Duchenne muscular dystrophy, research reveals

Swedish researchers develop new, low-cost method to examine individual leukemia cells

Crohn's disease appears to have two distinct genetic subtypes, study finds

Study provides insights into how species adapt to changing environments over many generations

Clinical Genomics’ blood test detects twice the number of colorectal cancer recurrence cases than CEA testing

Discovery of neuropilin 2 deficiency may lead to new therapies for edema and lymphedema

Researchers develop mouse model to investigate behavioral effects of eating disorder gene

Penn researchers receive $5.2 million NIH grant to study mechanisms that promote lung regeneration

Wayne State receives NIH funding to develop interventions for better asthma management in youth

OGT announces expansion of Cytocell Aquarius Haematology FISH probe range

New research reveals key protein involved in heart failure

New evolutionary analysis provides insights into how Zika virus spreads between populations

High folate intake may increase risk of peripheral neuropathy in older adults with common gene variant

Genome engineering-based methods pave way for new treatment of patients with sickle cell disease

Study identifies mechanistic link between maternal obesity and childhood hypertension

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