Gene News and Research

Latest Gene News and Research

Scientists discover reliable marker to spot CAFs in oral cancer tissues

For the first time, researchers have identified a reliable marker (PDGFRβ) to detect carcinoma-associated fibroblasts (cells within the tumor that encourage growth and metastasis) (CAFs) in oral cancer tissues. With this discovery, anti-PDGFRβ treatment could soon be combined with existing tumor treatments to provide a more effective cancer therapy.

11 May 2016

Jumping genes may play crucial role in generation of cancer

For more than 50 years, scientists have known of the existence of "jumping genes," strands of DNA material that can move from one location in the genome to another.

11 May 2016

New mouse model reveals underlying brain changes linked to autism's social, learning problems

A new mouse model of a genetically-linked type of autism reveals more about the role of genes in the disorder and the underlying brain changes associated with autism's social and learning problems.

11 May 2016

Study suggests ways of minimizing DNA folding errors

Induced pluripotent stem cells hold promise for regenerative medicine because they can, in theory, turn into any type of tissue and because they are made from a patient's own adult cells, guaranteeing compatibility. However, the technique that turns adult cells into these iPS cells is not foolproof; after reverting to their pluripotent state, these cells don't always correctly differentiate back into adult cells.

11 May 2016

Eating seafood once a week may protect against age-related memory loss

Eating a meal of seafood or other foods containing omega-3 fatty acids at least once a week may protect against age-related memory loss and thinking problems in older people, according to a team of researchers at Rush University Medical Center and Wageningen University in the Netherlands.

11 May 2016

Human gut model HuMiX represents actual conditions, processes that occur within intestines

One of the most complex human organs is the digestive tract: Here, the body comes into contact with all manner of diet-derived compounds and with countless bacteria.

11 May 2016

Researchers agree to test new stem cell gene therapy for Sanfilippo disease in human trial

Scientists in Manchester, who have developed a stem cell gene therapy to reverse a fatal childhood illness, have agreed to work with a new therapeutics company to test it in a human trial.

11 May 2016

Patient-specific immunotherapeutic vaccines may improve overall survival of melanoma patients

Two patients with melanoma that had spread to the liver survived for at least 8.5 and 12 years after resection of the hepatic tumor and treatment with patient-specific immunotherapeutic vaccines.

11 May 2016

Genetic variations that increase PKC alpha activity may influence development of Alzheimer's disease

In Alzheimer's disease, plaques of amyloid beta protein accumulate in the brain, damaging connections between neurons.

11 May 2016

MNI scientists move a step forward in efforts to treat hereditary spastic paraplegia

Scientists at the Montreal Neurological Institute and Hospital have identified novel gene mutations that cause hereditary spastic paraplegia (HSP), a step forward in efforts to treat this debilitating disease.

11 May 2016

Mice study reveals signs of stress-related early maturation in vital brain region

Intuition is all one needs to understand that stress in early childhood can create lifelong psychological troubles, but scientists have only begun to explain how those emerge in the brain.

11 May 2016

Titanium dioxide nanoparticles can have low-level effects on oxidative stress genes

A nanoparticle commonly used in food, cosmetics, sunscreen and other products can have subtle effects on the activity of genes expressing enzymes that address oxidative stress inside two types of cells.

11 May 2016

University of Glasgow-led study could lead to improved treatments for lymphoma, other cancers

A study by scientists at the University of Glasgow, which reveals the critical role a common cancer-associated gene plays in lymphoma development, could lead to improved treatments for a range of cancers.

11 May 2016

TSRI scientists expanding web services to improve biomedical research

A team of scientists at The Scripps Research Institute is expanding web services to make biomedical research more efficient. With their free, public projects, MyGene.info and MyVariant.info, researchers around the world have a faster way to spot new connections between genes and disease.

11 May 2016

EvOx Therapeutics raises £10m to target new therapeutic system for untreatable diseases

Oxford spinout EvOx Therapeutics will harness the body’s own precision communications system to deliver drugs to specific parts of the body, with the aim of treating conditions which are currently untreatable including those affecting the brain, as well as autoimmune diseases and cancers.

11 May 2016

Simultaneous DNA, RNA and protein analysis to enhance cancer immunology studies: an interview with Dr Joseph Beechem

Cancer immunology is all about how your immune cells are going to fight and kill your tumor cells. If you look at the pure genetic code of a T-cell that's going to kill your tumor compared to the same cell that has been “put-to-sleep” (by the tumor), the pure genetic DNA content of those two cells are identical.

From NanoString Technologies 11 May 2016

Profiling gamma-retrovirus integration sites may help identify genes linked to specific cancer types

Identifying the sites where gamma-retroviruses commonly insert into the genome may help to identify genes associated with specific cancer types, according to a study published April 20, 2016 in the open-access journal PLOS ONE by Kathryn Gilroy at the University of Glasgow, UK, and colleagues.

10 May 2016

Scientists identify role of non-coding elements in shaping human-specific traits

Human-specific variants of four microRNAs may have altered expression levels and gene targets compared to other great apes, according to a study published April 22, 2016 in the open-access journal PLOS ONE by Alicia Gallego from the Institute of Evolutionary Biology, Spain, and colleagues.

10 May 2016

Study highlights role of specific chromosomal deletion in cancer development, progression

In a typical cancer cell, up to one-quarter of the genome is lost due to large chromosomal deletions, while the concomitant loss of hundreds of genes creates vulnerabilities that are impossible to reveal through the study of individual genes. Prof. Anna Sablina and her team at VIB/KU Leuven optimized a workflow for the generation of cell lines with targeted chromosomal deletions.

10 May 2016

lncRNA in placenta may help protect unborn baby from invading pathogens

The human placenta is an organ unlike any other. During the course of nine months it is formed by the embryo, sustains life and then is shed.

10 May 2016

Gene News and Research

Latest Gene News and Research

Scientists discover reliable marker to spot CAFs in oral cancer tissues

Jumping genes may play crucial role in generation of cancer

New mouse model reveals underlying brain changes linked to autism's social, learning problems

Study suggests ways of minimizing DNA folding errors

Eating seafood once a week may protect against age-related memory loss

Human gut model HuMiX represents actual conditions, processes that occur within intestines

Researchers agree to test new stem cell gene therapy for Sanfilippo disease in human trial

Patient-specific immunotherapeutic vaccines may improve overall survival of melanoma patients

Genetic variations that increase PKC alpha activity may influence development of Alzheimer's disease

MNI scientists move a step forward in efforts to treat hereditary spastic paraplegia

Mice study reveals signs of stress-related early maturation in vital brain region

Titanium dioxide nanoparticles can have low-level effects on oxidative stress genes

University of Glasgow-led study could lead to improved treatments for lymphoma, other cancers

TSRI scientists expanding web services to improve biomedical research

EvOx Therapeutics raises £10m to target new therapeutic system for untreatable diseases

Simultaneous DNA, RNA and protein analysis to enhance cancer immunology studies: an interview with Dr Joseph Beechem

Profiling gamma-retrovirus integration sites may help identify genes linked to specific cancer types

Scientists identify role of non-coding elements in shaping human-specific traits

Study highlights role of specific chromosomal deletion in cancer development, progression

lncRNA in placenta may help protect unborn baby from invading pathogens

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting