Genetics News and Research

Latest Genetics News and Research

Faulty glucose transport weakens insulin release in Type 2 diabetes

Just as smart traffic management ensures smooth vehicular movement during peak hours, our body relies on a molecular traffic system to manage the surge in glucose levels after a meal.

18 Aug 2025

Fucosylation emerges as a key player in digestive inflammatory diseases and cancers

Fucosylation, a crucial post-translational modification, has emerged as a significant factor influencing digestive inflammatory diseases and cancers.

18 Aug 2025

Mitochondrial metabolite glutathione plays key role in breast cancer metastasis

The mitochondria may be the powerhouse of the cell, but mounting evidence suggests this organelle is also a driving force behind cancer.

18 Aug 2025

Targeting mitochondrial biogenesis to improve outcomes in acute kidney injury

Acute kidney injury (AKI) remains a significant global health challenge, with high mortality rates and the potential for progression to chronic kidney disease.

18 Aug 2025

Exploring the complex origins of endothelial cells in tumor angiogenesis

This newly published review article offers a comprehensive examination of the complexities of tumor angiogenesis and the origins of endothelial cells (ECs) within tumors.

18 Aug 2025

Alzheimer’s gene risks differ by ancestry, major study reveals 133 new variants

Researchers used whole-genome sequencing from diverse populations to identify 156 variants, including 133 novel ones, linked to Alzheimer’s disease and related dementias. The study highlights ancestry-specific genetic risk and protective factors, challenging one-size-fits-all approaches to dementia genetics.

17 Aug 2025

Dementia-like protein clumping found in early pancreatic cancer cells

Cancer Research UK-funded scientists have uncovered dementia-like behaviour in pancreas cells at risk of turning into cancer. The findings provide clues that could help in the treatment and prevention of pancreatic cancer, a difficult-to-treat disease linked to 6,900 deaths in the UK every year.

17 Aug 2025

Engineered telomerase RNA offers temporary boost to telomere length in human stem cells

Much the way the caps on the ends of a shoelace prevent it from fraying, telomeres - regions of repetitive DNA sequences and a protein structure - protect the tips of chromosomes from damage.

14 Aug 2025

Origin-recognition complex plays a broad role in the regulation of gene expression

Origin-recognition complex, or ORC, plays an unexpectedly broad role in the regulation of human cell gene expression, according to a study in the journal Cell Reports.

14 Aug 2025

Targeting ferroptosis to eliminate therapy-resistant cancer stem cells

Recent advancements in cancer research are shedding light on a novel therapeutic strategy aimed at overcoming the formidable challenge of cancer stem cells (CSCs).

14 Aug 2025

How circadian biology shapes intestinal regeneration and health

The interplay between the circadian clock, intestinal stem cell niche, and epithelial cell fate is shaping our understanding of how gut homeostasis and cellular regeneration are regulated.

14 Aug 2025

Scientists decode inner speech from brain activity with high accuracy

Scientists have pinpointed brain activity related to inner speech-the silent monologue in people's heads-and successfully decoded it on command with up to 74% accuracy.

14 Aug 2025

Dual epigenetic marks found to regulate cell identity

Shedding light on what determines how cells become what they are meant to be-nerves, bone, muscles, etc.-can also help researchers understand how diseases develop when these biological programs break down.

14 Aug 2025

Smartwatch data helps identify daily activities in real life

Researchers have long been able to use information from smartwatches to identify physical movement, such as sitting or walking, that wearers are performing in a controlled lab setting.

14 Aug 2025

Engineered CD40 antibody shrinks tumors and induces remission

Over the past 20 years, a class of cancer drugs called CD40 agonist antibodies have shown great promise-and induced great disappointment.

14 Aug 2025

New drug discovery platform aims to deliver first-in-class therapies

65LAB has awarded US$1.5 million (approx. S$1.9 million) to Professor Enrico Petretto to advance a breakthrough drug discovery platform developed at Duke-NUS Medical School. The project aims to deliver first-in-class antifibrotic therapies for lung and kidney diseases-conditions that currently have no effective treatment.

14 Aug 2025

Disrupting dopamine pathway stops threadworms from burrowing into the skin

Threadworms, which are a type of parasitic nematode, spend a lot of time crawling around on human skin, poking and prodding to find the best place for entry before burrowing in.

13 Aug 2025

Leading organizations announce research initiative to uncover why ALS affects high-performing populations

Answer ALS, in collaboration with ALS Therapy Development Institute (ALS TDI) and Augie's Quest, today announced plans to launch Champion Insights, an ambitious research initiative designed to uncover critical genetic and metabolic mechanisms that may explain the significantly higher incidence of amyotrophic lateral sclerosis (ALS) among endurance athletes, military service members, and potentially other high-performing populations.

13 Aug 2025

Finnish study reveals why the longest-lived region doesn’t follow Blue Zone rules

Researchers examined four regions in Western Finland to see if any met Blue Zone lifestyle principles and matched high longevity, finding that the most long-lived area, Åland, had top health but low lifestyle adherence, while Swedish-speaking Ostrobothnia showed promising, but unconfirmed potential.

12 Aug 2025

AI discovers promising antibiotic compounds in Archaea microbes

They've survived for billions of years in boiling acid, deep-sea vents and salt flats. Now, some of Earth's oldest life forms - microbes called Archaea - are offering a new weapon in the fight against one of today's most urgent health threats: antibiotic resistance.

12 Aug 2025

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Genetics News and Research

Latest Genetics News and Research

Faulty glucose transport weakens insulin release in Type 2 diabetes

Fucosylation emerges as a key player in digestive inflammatory diseases and cancers

Mitochondrial metabolite glutathione plays key role in breast cancer metastasis

Targeting mitochondrial biogenesis to improve outcomes in acute kidney injury

Exploring the complex origins of endothelial cells in tumor angiogenesis

Alzheimer’s gene risks differ by ancestry, major study reveals 133 new variants

Dementia-like protein clumping found in early pancreatic cancer cells

Engineered telomerase RNA offers temporary boost to telomere length in human stem cells

Origin-recognition complex plays a broad role in the regulation of gene expression

Targeting ferroptosis to eliminate therapy-resistant cancer stem cells

How circadian biology shapes intestinal regeneration and health

Scientists decode inner speech from brain activity with high accuracy

Dual epigenetic marks found to regulate cell identity

Smartwatch data helps identify daily activities in real life

Engineered CD40 antibody shrinks tumors and induces remission

New drug discovery platform aims to deliver first-in-class therapies

Disrupting dopamine pathway stops threadworms from burrowing into the skin

Leading organizations announce research initiative to uncover why ALS affects high-performing populations

Finnish study reveals why the longest-lived region doesn’t follow Blue Zone rules

AI discovers promising antibiotic compounds in Archaea microbes

Sequencing & Genomics: Elevating Science and Healthcare eBook

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR