Genetics News and Research

Latest Genetics News and Research

Exploring the role of SNPs in early diagnosis of coronary microvascular dysfunction

A new review highlights the potential role of single nucleotide polymorphisms (SNPs) in improving the early diagnosis and targeted intervention of coronary microvascular dysfunction (CMD)—a condition linked to myocardial ischemia despite the absence of major artery blockages.

26 Feb 2025

Microphysiological systems in drug discovery

NewsMedical speaks with CN Bio about the translatability between in vitro organ-on-a-chip (OOC) models, microphysiological systems, and their in vivo counterparts.

From CN Bio Innovations Ltd 26 Feb 2025

New low-cost tool could revolutionize type 2 diabetes treatment

Millions of people with type 2 diabetes could receive better treatment thanks to a new, simple low-cost tool, according to groundbreaking research announced today at the Diabetes UK Professional Conference 2025 and published in the Lancet.

26 Feb 2025

Single-cell analysis reveals key chondrocyte subpopulations in osteoarthritis

Chondrocytes are specialized cells that are essential for cartilage maintenance and repair, and their dysfunction is central to the development of joint diseases like osteoarthritis (OA).

26 Feb 2025

New tool could revolutionize brain tumor surgery with rapid cancer cell detection

A novel tool for rapidly identifying the genetic "fingerprints" of cancer cells may enable future surgeons to more accurately remove brain tumors while a patient is in the operating room, new research reveals.

25 Feb 2025

Can coffee push back Parkinson’s? New study uncovers key genetic link

Higher coffee consumption is causally linked to delayed onset of Parkinson’s disease but does not affect disease risk or progression, according to a Mendelian randomization study.

25 Feb 2025

Breast cancer cases and deaths set to surge by 2050—are we prepared?

A global study finds that breast cancer cases will rise by 38% and deaths by 68% by 2050, with the highest incidence in Australia and New Zealand and worsening mortality in low-income countries.

25 Feb 2025

Researchers challenge previous understanding of tumor growth in NF-1

Despite what was previously thought, new research has shown that genetic changes alone cannot explain why and where tumors grow in those with genetic condition neurofibromatosis type 1 (NF-1).

25 Feb 2025

Mass General Brigham study uncovers 16 novel Alzheimer's risk genes

Investigators from Mass General Brigham have conducted a multi-ancestry, whole genome sequencing association study of Alzheimer's disease and found evidence for 16 new susceptibility genes, expanding the study of Alzheimer's disease in underrepresented groups.

25 Feb 2025

Early lung cancer diagnosis improved with ctDNA methylation biomarkers

Early diagnosis of lung cancer is a critical priority in clinical practice. It may help reduce the rate of lung-cancer-related mortality, extend disease-free survival, and allow patients to live without ongoing medical interventions and complications.

25 Feb 2025

Review highlights next-generation cancer therapies targeting PIK3CA mutations

A newly published review in Genes & Diseases explores the oncogenic activation of PIK3CA in cancer and highlights emerging targeted therapies designed to improve treatment efficacy while reducing side effects.

25 Feb 2025

New insights into mTOR pathway offer hope for diabetic nephropathy treatment

A newly published study in Genes & Diseases highlights the crucial role of the mammalian target of rapamycin (mTOR) pathway in the progression of diabetic nephropathy (DN) and explores its potential as a therapeutic target.

25 Feb 2025

Genetic study demonstrates fat-selective weight loss with GLP-1 agonist use

Diabetes and obesity have become pressing health issues worldwide. Glucagon-like peptide-1 (GLP-1) receptor agonists, a class of medications widely used in the treatment of type 2 diabetes (T2D), have shown significant effectiveness in both lowering blood sugar levels and aiding weight loss due to their unique pharmacological mechanisms.

25 Feb 2025

Machine learning algorithm decodes immune system’s hidden data for disease detection

Your immune system harbors a lifetime's worth of information about threats it's encountered - a biological Rolodex of baddies.

24 Feb 2025

New AI tool measures brain aging speed and predicts cognitive health

A new artificial intelligence model measures how fast a patient's brain is aging and could be a powerful new tool for understanding, preventing and treating cognitive decline and dementia, according to USC researchers.

24 Feb 2025

Study unlocks key differences in heart inflammation

A group of Berlin researchers in collaboration with international scientists have found differences in heart inflammation caused by COVID-19, anti-COVID-19 vaccination, and non-COVID-19 myocarditis.

24 Feb 2025

High GATA6 expression predicts improved outcomes in pancreatic cancer

This new review article highlights the crucial role of GATA6, a transcription factor, in pancreatic ductal adenocarcinoma (PDA). The article explores GATA6's dual role in cancer progression and its potential as a biomarker and treatment target.

24 Feb 2025

Study unravels the complex interplay of the UPS in cancer development and treatment

A new review published in Genes & Diseases explores the pivotal role of the ubiquitin-proteasome system (UPS) in regulating the tumor microenvironment (TME) and driving cancer progression. The study provides novel insights into how ubiquitination and deubiquitination impact tumor cells, immune responses, and potential therapeutic strategies for cancer treatment.

24 Feb 2025

Unveiling the role of FAM20C in disease and cancer treatment

A new review published in Genes & Diseases explores the multifaceted role of FAM20C, a Golgi protein kinase, in disease progression.

23 Feb 2025

Aging isn’t just in your genes—your environment plays a bigger role, study shows

Study explores the relative contributions of genetics and environmental factors to aging and premature mortality. It highlights how the exposome—lifetime environmental exposures—shapes disease risks, with socioeconomic status, smoking, and lifestyle choices emerging as key aging determinants.

23 Feb 2025