Genetics News and Research

Latest Genetics News and Research

Arthritis and COPD together raise mortality risk

People with chronic obstructive pulmonary disease (COPD) and arthritis have a higher risk of death than people with arthritis who do not have COPD, according to a new study.

11 Mar 2025

PlasticHeal project sheds light on hidden health effects of nanoplastics

Microplastics and nanoplastics, two of the smallest and most invisible forms of plastic pollution, may pose risks to human health.

11 Mar 2025

Novel regulators in digestive tract disease progression and treatment

This new article published in Genes & Diseases highlights the critical role of tRNA-derived small RNAs (tsRNAs) in digestive tract diseases, positioning these molecules as potential biomarkers for diagnosis, prognosis, and targeted therapies. The comprehensive review explores the biogenesis, classification, and biological functions of tsRNAs, shedding light on their influence over cellular processes such as translation regulation, epigenetic modification, and protein interactions.

11 Mar 2025

Study reveals the role of transcription factors as therapeutic gateways in MAFLD

Metabolic dysfunction-associated fatty liver disease (MAFLD) has become a growing global health concern, affecting millions worldwide. This complex liver disorder ranges from simple steatosis to more severe forms, including metabolic dysfunction-associated steatohepatitis (MASH), which may progress to fibrosis, cirrhosis, and even liver cancer.

11 Mar 2025

Decoding programmed cell death in breast cancer

This review highlights the critical role of ubiquitin-specific proteases (USPs) in regulating programmed cell death (PCD) in breast cancer (BC). As the most prevalent malignant tumor among women, BC remains a significant global health challenge.

11 Mar 2025

Study highlights the role of ELF4 as a key transcription factor in development, immunity, and oncology

ELF4, a transcription factor belonging to the ETS family, has emerged as a pivotal regulator in cell differentiation, immune system function, and cancer progression. This newly published review underscores its molecular complexity and clinical significance, shedding light on its dual role in tumor suppression and oncogenesis.

11 Mar 2025

Deciphering the tumor-immune interplay in endometrial carcinoma

A new review article published in Genes & Diseases sheds light on the complex molecular mechanisms through which tumor-infiltrating immune cells regulate endometrial carcinoma (EC). As one of the most prevalent gynecological cancers, EC continues to challenge researchers and clinicians due to its dynamic interaction with the immune microenvironment.

11 Mar 2025

Study reveals TCM-Based strategies for ferroptosis modulation

Innovative insights into the role of ferroptosis, a unique form of programmed cell death, are reshaping the landscape of disease treatment. This growing field highlights how Traditional Chinese Medicine (TCM) can effectively modulate ferroptosis, offering novel therapeutic approaches for various conditions, including cancer, cardiovascular diseases, neurodegenerative disorders, and organ injuries.

11 Mar 2025

Harnessing lncRNAs for early diagnosis and intervention in acute kidney injury

A new review published in Genes & Diseases on long non-coding RNAs (lncRNAs) highlights their critical role in the development, diagnosis, and potential treatment of acute kidney injury (AKI) and chronic kidney disease (CKD). The findings emphasize the importance of exosomal lncRNAs, which function as molecular regulators in kidney pathology and hold promise for future biomarker discovery and therapeutic advancements.

11 Mar 2025

Limiting screen time and promoting physical activity may help safeguard children’s mental health

A recent Finnish study suggests that limiting screen time and promoting physical activity from childhood may help safeguard mental health in adolescence.

10 Mar 2025

Walking more steps and exercise linked to lower risk of death in postmenopausal cancer survivors

Among postmenopausal women with a history of cancer, taking more daily steps and engaging in moderate-to-vigorous physical activity were both associated with a significantly reduced risk of death from cardiovascular disease, according to preliminary research presented at the American Heart Association's Epidemiology and Prevention | Lifestyle and Cardiometabolic Health Scientific Sessions 2025.

10 Mar 2025

Understanding the role of LSD1 in cellular processes and disease

A new review highlights the pivotal role of LSD1 (lysine-specific demethylase 1) in regulating critical cellular processes and its implications for human diseases.

8 Mar 2025

Unraveling the genetic differences between LUAD and LUSC in lung cancer

Lung cancer remains one of the leading causes of cancer-related mortality, with lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC) representing the most prevalent subtypes of non-small cell lung cancer (NSCLC).

8 Mar 2025

Circular RNA plays key role in cancer biology and therapy

A new review article highlights the transformative role of circular RNA (circRNA) in cancer, revealing its potential as both a key player in tumor biology and a promising avenue for future therapies.

8 Mar 2025

Ubiquitination plays a key role in cancer stem cell function and treatment resistance

This review highlights the critical role of ubiquitination in governing the functionality of cancer stem cells (CSCs), shedding light on potential therapeutic targets for combating tumor progression, recurrence, and drug resistance.

8 Mar 2025

EZH2 inhibition offers hope for fighting treatment-resistant cancers

The critical role of EZH2, an essential epigenetic regulator, in cancer progression and treatment is underscored in this new review article published in Genes & Diseases.

8 Mar 2025

Research reveals genetic connection between obesity in dogs and humans

Researchers studying British Labrador retrievers have identified multiple genes associated with canine obesity and shown that these genes are also associated with obesity in humans.

6 Mar 2025

Study finds link between pregnancy mineral levels and lower blood pressure in midlife

Women with higher levels of essential minerals circulating in their blood during pregnancy, particularly copper and manganese, along with vitamin B12, had a lower risk of developing high blood pressure in middle age, about 20 years later, according to research presented at the American Heart Association's Epidemiology and Prevention | Lifestyle and Cardiometabolic Health Scientific Sessions 2025.

6 Mar 2025

Pacific Islander, Native Hawaiian and Asian American populations show varying heart disease risk factors

Asian American, Native Hawaiian and other Pacific Islander (AANHPI) populations experienced differences in both cardiovascular disease predicted risk and risk factors, according to preliminary research presented at the American Heart Association's Epidemiology and Prevention | Lifestyle and Cardiometabolic Health Scientific Sessions 2025.

6 Mar 2025

New research links early-life microbes to long-term metabolic health

The microbiome shapes development of insulin-producing cells in infancy, leading to long-term changes in metabolism and diabetes risk, new research in mice has found.

6 Mar 2025

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Genetics News and Research

Latest Genetics News and Research

Arthritis and COPD together raise mortality risk

PlasticHeal project sheds light on hidden health effects of nanoplastics

Novel regulators in digestive tract disease progression and treatment

Study reveals the role of transcription factors as therapeutic gateways in MAFLD

Decoding programmed cell death in breast cancer

Study highlights the role of ELF4 as a key transcription factor in development, immunity, and oncology

Deciphering the tumor-immune interplay in endometrial carcinoma

Study reveals TCM-Based strategies for ferroptosis modulation

Harnessing lncRNAs for early diagnosis and intervention in acute kidney injury

Limiting screen time and promoting physical activity may help safeguard children’s mental health

Walking more steps and exercise linked to lower risk of death in postmenopausal cancer survivors

Understanding the role of LSD1 in cellular processes and disease

Unraveling the genetic differences between LUAD and LUSC in lung cancer

Circular RNA plays key role in cancer biology and therapy

Ubiquitination plays a key role in cancer stem cell function and treatment resistance

EZH2 inhibition offers hope for fighting treatment-resistant cancers

Research reveals genetic connection between obesity in dogs and humans

Study finds link between pregnancy mineral levels and lower blood pressure in midlife

Pacific Islander, Native Hawaiian and Asian American populations show varying heart disease risk factors

New research links early-life microbes to long-term metabolic health

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