Genetics News and Research

Latest Genetics News and Research

New, one-stop method developed to avoid de novo genetic disease in embryos

De novo variants (DNVs), genetic mutations that were not previously identifiable in the family history of one of two prospective parents, may cause disease in any children they have.

31 Aug 2021

Finding the genetic cause of childhood epilepsy helps improve treatment and care

Epilepsy is one of the most common chronic neurological diseases, affecting more than 50 million people worldwide. Although it is believed that a large proportion of childhood-onset epilepsies are caused by genetic changes, it remains unknown precisely how many of these patients suffer from a genetic disorder and how often the treatment can be targeted to their specific genetic alteration.

31 Aug 2021

Research sheds light on potential biological mechanisms that impact adherence to medications

How strictly patients follow a prescribed drug treatment (drug adherence) is clearly important if the therapy is to have maximum effect. A number of things can affect adherence, including behavioral and socioeconomic factors, but to date there have been few investigations into the role played by genetics. Now, research to be presented at the annual conference of the European Society of Human Genetics today has thrown new light on the potential biological mechanisms that can affect adherence to treatment.

31 Aug 2021

Genetic tests can provide a better picture of cardiovascular disease risk than blood tests

Determining an individual's blood group based on genetic tests instead of merely traditional blood tests can provide a better picture of the risk of cardiovascular diseases.

30 Aug 2021

Polygenic risk scores could be used as a tool to help diagnose epilepsy

Although epilepsy is a relatively common condition, affecting approximately 1% of individuals worldwide, it is often difficult to diagnose in clinical practice, and it is estimated that up to a quarter of all cases may be misdiagnosed initially.

30 Aug 2021

Molecular autopsy of dried blood spots can identify underlying cause of sudden cardiac death in a young person

The underlying cause of sudden cardiac death (SCD) in a young person is often difficult to identify. A genetic analysis could provide more information in many cases, but blood samples are not collected routinely at the time of death, and DNA extracted from the tissues collected at autopsy is damaged because of the way they are fixed in formalin and paraffin-embedded.

30 Aug 2021

Study may pave way for new treatment strategies to limit the progression of solid tumors

Researchers at the University of British Columbia's faculty of medicine and BC Cancer Research Institute have uncovered a weakness in a key enzyme that solid tumour cancer cells rely on to adapt and survive when oxygen levels are low.

28 Aug 2021

Large analysis identifies 579 genetic locations linked to anti-social behavior and addiction

An analysis of data from 1.5 million people has identified 579 locations in the genome associated with a predisposition to different behaviors and disorders related to self-regulation, including addiction and child behavioral problems.

27 Aug 2021

New MOGONET outperforms existing supervised multi-omics integrative analysis approaches

Genomics, proteomics, metabolomics, transcriptomics -- rapid advances in high-throughput biomedical technologies has enabled the collection of data with unprecedented detail from the growing number of omics.

27 Aug 2021

Study identifies 579 genomic regions associated with predisposition to self-regulating behaviors

Researchers have identified 579 locations in the human genome associated with a predisposition to self-regulation-related behaviors, including addiction and child behavioral problems. With data from 1.5 million people of European descent, the effort is considered to be one of the largest genome-wide association studies to date.

26 Aug 2021

Aging reduces the risk of developing genetically related diseases

Unexpected findings provide insights into how aging and genetically determined diseases are associated.

26 Aug 2021

Research offers new insight into how to treat endometriosis

Endometriosis is a painful, chronic condition in which tissue from the uterus inappropriately grows outside the uterus.

26 Aug 2021

Study uncovers epigenetic mechanisms that promote glioma tumor growth

Northwestern Medicine investigators have discovered the epigenetic mechanisms involved in the regulation of multiple oncogenes in glioma cells, mechanisms that promote overall glioma tumor growth and resistance to therapy, according to a study published in the journal Clinical Cancer Research.

25 Aug 2021

Researchers find clues to how lung damage develops in the aftermath of a respiratory infection

The deadliest time in a viral respiratory illness sometimes is actually after the virus is cleared from the body. Destructive processes that are set in motion during an infection crest in the weeks after the virus is defeated, leading to organ damage that can cause chronic illness or even death.

24 Aug 2021

First-in-kind kidney cancer drug developed at UTSW receives FDA approval

A first-in-kind kidney cancer drug developed from laboratory and translational studies conducted at UT Southwestern Medical Center received approval from the Food and Drug Administration, providing a new treatment for patients with familial kidney cancer.

24 Aug 2021

Researchers develop brain organoids that show neural activity similar to living human brains

Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have developed brain organoids - 3D, brain-like structures grown from human stem cells - that show organized waves of activity similar to those found in living human brains.

24 Aug 2021

Genetics News and Research

Latest Genetics News and Research

New, one-stop method developed to avoid de novo genetic disease in embryos

Finding the genetic cause of childhood epilepsy helps improve treatment and care

Research sheds light on potential biological mechanisms that impact adherence to medications

Genetic tests can provide a better picture of cardiovascular disease risk than blood tests

Polygenic risk scores could be used as a tool to help diagnose epilepsy

Molecular autopsy of dried blood spots can identify underlying cause of sudden cardiac death in a young person

Study may pave way for new treatment strategies to limit the progression of solid tumors

Large analysis identifies 579 genetic locations linked to anti-social behavior and addiction

New MOGONET outperforms existing supervised multi-omics integrative analysis approaches

Study identifies 579 genomic regions associated with predisposition to self-regulating behaviors

Aging reduces the risk of developing genetically related diseases

Research offers new insight into how to treat endometriosis

Study uncovers epigenetic mechanisms that promote glioma tumor growth

Researchers find clues to how lung damage develops in the aftermath of a respiratory infection

First-in-kind kidney cancer drug developed at UTSW receives FDA approval

Researchers develop brain organoids that show neural activity similar to living human brains

Rice bioengineer receives Trailblazer Award to develop technology for reprogramming immune cells

Researchers unravel pathomechanisms involved in Chronic Fatigue Syndrome

VALIDATE Network’s TB vaccine work receives $1.5 million funding boost

New AI blood test found to detect over 90% of lung cancers

eBook: Using iPSCs models for human disease research and drug discovery eBook

How innovation in dried blood spot testing is transforming neurological disease monitoring

Unlocking live single-cell functional insights

How microRNA is transforming science: From discovery to diagnostics