Genetics News and Research

Latest Genetics News and Research

Phase I study of selumetinib drug shows partial response in pediatric neural tumors

In an early-phase clinical trial of a new oral drug, selumetinib, children with the common genetic disorder neurofibromatosis type 1 (NF1) and plexiform neurofibromas, tumors of the peripheral nerves, tolerated selumetinib and, in most cases, responded to it with tumor shrinkage.

29 Dec 2016

Fred Hutch’s new Evergreen Fund to promote commercialization of research into lifesaving therapies

Fred Hutchinson Cancer Research Center announced its first-ever grants from its newly established Evergreen Fund to spur researchers' efforts to advance bold ideas toward creating or partnering with a commercial entity.

28 Dec 2016

Mutations linked to endometrial cancer can be detected in uterine lavage fluid, study reveals

Mutations that have been linked to endometrial cancer can be found in the uterine lavage fluid of pre- and post-menopausal women both with and without detectable cancer, according to a study published in PLOS Medicine by John Martignetti from the Icahn School of Medicine at Mount Sinai, New York, USA, and colleagues.

28 Dec 2016

Study identifies new mechanism of how inhibitory brain cells develop

Scientists have discovered that networks of inhibitory brain cells or neurons develop through a mechanism opposite to the one followed by excitatory networks.

27 Dec 2016

Experimental Ebola vaccine offers high protection against deadly virus, reveals major trial

An experimental Ebola vaccine was highly protective against the deadly virus in a major trial in Guinea, according to results published today in The Lancet. The vaccine is the first to prevent infection from one of the most lethal known pathogens, and the findings add weight to early trial results published last year.

23 Dec 2016

Inherited CD70 deficiency increases susceptibility to Epstein-Barr virus and EBV-related cancer

Investigators at the National Institutes of Health and international colleagues have identified a genetic immune disorder characterized by increased susceptibility and poor immune control of Epstein-Barr virus (EBV) and, in some cases, an EBV-associated cancer called Hodgkin's lymphoma.

23 Dec 2016

Linking human genome sequences to EHR information could influence clinical medicine, says expert

The value of intersecting the sequencing of individuals' exomes or full genomes to find rare genetic variants -- on a large scale -- with their detailed electronic health record information has "myriad benefits, including the illumination of basic human biology, the early identification of preventable and treatable illnesses, and the identification and validation of new therapeutic targets," wrote Daniel J. Rader, MD, chair of the Department of Genetics, in the Perelman School of Medicine at the University of Pennsylvania, in Science this week, with Scott M. Damrauer, MD, an assistant professor of Surgery at Penn and the Veterans Affairs Medical Center in Philadelphia.

23 Dec 2016

Scientists discover OGDHL and NRD1 genes linked to progressive loss of neurological function

An international team of scientists has discovered that the gene, OGDHL, a key protein required for normal function of the mitochondria -- the energy-producing factory of the cell -- and its chaperone, nardilysin (NRD1) are linked to progressive loss of neurological function in humans.

22 Dec 2016

Scientists identify gene variants causing unrecognized developmental disorder

An international team of scientists has identified variants of the gene EBF3 causing a developmental disorder with features in common with autism.

22 Dec 2016

New study explores circadian timekeeping to create genetic knock-out rescue mice

A new study from the laboratory of Hiroki Ueda at the RIKEN Quantitative Biology Center investigates circadian timekeeping with a novel approach to creating genetic knock-out rescue mice.

22 Dec 2016

Researchers use mathematical models to explain how bacteria, cancer cells exploit bet-hedging

Modern medicine and treatments for bacterial infections and cancer have significantly increased life spans and improved quality-of-life. However, many drugs eventually fail because of the outgrowth and survival of treatment-resistant populations.

22 Dec 2016

Discrimination interacts with certain genetic variants to negatively impact health

It's no secret that discrimination is stressful for those who experience it, but turns out the issue is more than skin deep—these stressors can interact with our genetics to negatively impact our health, a new University of Florida study shows.

22 Dec 2016

Music may regulate mood, emotional responses at behavioral and neuronal level

Sounds, such as music and noise, are capable of reliably affecting individuals' moods and emotions, possibly by regulating brain dopamine, a neurotransmitter strongly involved in emotional behavior and mood regulation.

21 Dec 2016

Popular food supplement may be key in reversing detrimental effects of Familial Dysautonomia

A new Tel Aviv University study finds that a popular food supplement called phosphatidylserine may be instrumental in reversing the detrimental effects of Familial Dysautonomia (FD), a debilitating neurodegenerative disorder that affects approximately 1 in 31 Jewish people of Eastern European, or Ashkenazi, ancestry.

21 Dec 2016

Danish researchers uncover bacteria’s secret code language

Antibiotic resistance in pathogenic bacteria is a growing global challenge. Danish researchers have now discovered that bacteria use a code language to avoid being controlled.

21 Dec 2016

Sanford study explores protein's role in improving survival of ovarian cancer patients

A Sanford Research lab is studying a protein's role in improving survival in ovarian cancer patients. Findings published in Oncogenesis indicate a higher level of a specific protein correlates with an increased survival rate and decrease in the spreading of cancer cells.

21 Dec 2016

Wellcome Trust Sanger Institute establishes spin-out company, Microbiotica

Cambridge Innovation Capital plc, a Cambridge-based investor in technology and healthcare companies, and IP Group plc, the developer of intellectual property-based businesses, announce the creation of Microbiotica Ltd, a newly formed spin-out company from the UK’s Wellcome Trust Sanger Institute based at the Wellcome Genome Campus in Hinxton, Cambridge.

21 Dec 2016

Study finds chances for recovery of women with anorexia or bulimia nervosa

A study from Massachusetts General Hospital (MGH) investigators finds that, contrary to what is often believed, around two thirds of women with anorexia nervosa or bulimia nervosa will eventually recover from their eating disorders.

21 Dec 2016

Bionic pancreas system manages blood sugar levels in patients with type 1 diabetes living at home

The bionic pancreas system developed by Boston University investigators proved better than either conventional or sensor-augmented insulin pump therapy at managing blood sugar levels in patients with type 1 diabetes living at home, with no restrictions, over 11 days.

20 Dec 2016

White matter microstructure in children linked to cognitive development

A new study led by UNC School of Medicine researchers concluded that patterns of white matter microstructure present at birth and that develop after birth predict the cognitive function of children at ages 1 and 2.

20 Dec 2016

Genetics News and Research

Latest Genetics News and Research

Phase I study of selumetinib drug shows partial response in pediatric neural tumors

Fred Hutch’s new Evergreen Fund to promote commercialization of research into lifesaving therapies

Mutations linked to endometrial cancer can be detected in uterine lavage fluid, study reveals

Study identifies new mechanism of how inhibitory brain cells develop

Experimental Ebola vaccine offers high protection against deadly virus, reveals major trial

Inherited CD70 deficiency increases susceptibility to Epstein-Barr virus and EBV-related cancer

Linking human genome sequences to EHR information could influence clinical medicine, says expert

Scientists discover OGDHL and NRD1 genes linked to progressive loss of neurological function

Scientists identify gene variants causing unrecognized developmental disorder

New study explores circadian timekeeping to create genetic knock-out rescue mice

Researchers use mathematical models to explain how bacteria, cancer cells exploit bet-hedging

Discrimination interacts with certain genetic variants to negatively impact health

Music may regulate mood, emotional responses at behavioral and neuronal level

Popular food supplement may be key in reversing detrimental effects of Familial Dysautonomia

Danish researchers uncover bacteria’s secret code language

Sanford study explores protein's role in improving survival of ovarian cancer patients

Wellcome Trust Sanger Institute establishes spin-out company, Microbiotica

Study finds chances for recovery of women with anorexia or bulimia nervosa

Bionic pancreas system manages blood sugar levels in patients with type 1 diabetes living at home

White matter microstructure in children linked to cognitive development

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