Genetics News and Research

Latest Genetics News and Research

European Commission approves extended indication for Amgen's Kyprolis (carfilzomib) for the treatment of relapsed multiple myeloma patients

Amgen has announced that the European Commission (EC) has approved a variation to the marketing authorization for Kyprolis® (carfilzomib) to include use in combination with dexamethasone alone for adult patients with multiple myeloma who have received at least one prior therapy. The extended indication marks the second approval for Kyprolis by the EC in less than a year.

6 Jul 2016

Researchers identify astroglia-mediated mechanism for causing FXS symptoms in mice

A study published today in the Journal of Neuroscience led by Yongjie Yang of Tufts University School of Medicine identifies an astroglial trigger mechanism as contributing to symptoms of fragile X syndrome in mice.

6 Jul 2016

Scientists discover new genetic variations linked to increased myeloma risk

Researchers have identified eight new genetic variations in the human genome that could be linked to an increased risk of developing myeloma. The findings provide additional evidence and build on existing research that suggests myeloma can run in families.

5 Jul 2016

LouLou Foundation, ODC announce 11 new grants for research on CDKL5 deficiency

LouLou Foundation and the Orphan Disease Center (ODC) in the Perelman School of Medicine at the University of Pennsylvania are pleased to announce the award of 11 new research grants into CDKL5 deficiency - a rare X-chromosome-linked genetic disorder that causes severe neuro-developmental impairment and early-onset, difficult-to-control seizures.

5 Jul 2016

Scientists identify genetic mutations linked to synchronous colorectal cancers

Researchers have identified genetic mutations affecting the immune system which may lead to the development of more than one bowel tumour at the same time. Understanding how these cancers develop could improve targeting of therapies, according to the study published in Nature Communications.

5 Jul 2016

Novel technique could help discover genes linked to complex traits in any animal model

Mice are one of the most commonly used laboratory organisms, widely used to study everything from autism to infectious diseases. Yet genomic studies in mice have lagged behind those in humans.

4 Jul 2016

Study shows how genetic variants control immune cell response to pathogens

A study that is first in its kind and published in Nature Medicine today has looked at how far genetic factors control the immune cell response to pathogens in healthy individuals.

4 Jul 2016

Scientists develop light-activated injectable device to stimulate nerve cells

In the campy 1966 science fiction movie "Fantastic Voyage," scientists miniaturize a submarine with themselves inside and travel through the body of a colleague to break up a potentially fatal blood clot. Right. Micro-humans aside, imagine the inflammation that metal sub would cause.

4 Jul 2016

Risk of blindness from spinal-fusion surgery has declined, study shows

The risk of blindness caused by spinal fusion, one of the most common surgeries performed in the U.S., has dropped almost three-fold since the late 1990s, according to the largest study of the topic to date.

1 Jul 2016

Women with BRCA1 gene mutation at increased risk of aggressive uterine cancer

Women who carry the BRCA1 gene mutation that dramatically increases their risk of breast and ovarian cancers are also at higher risk for a lethal form of uterine cancer, according to a study led by a Duke Cancer Institute researcher.

1 Jul 2016

Recommendations for integrating genomic results into clinical practice

A quiet transformation has been brewing in medicine, as large-scale DNA results become increasingly available to patients and healthcare providers.

1 Jul 2016

Study links alpha-defensin genes to IgA nephropathy risk

A gene which forms part of our body's first line of defence against infection may be associated with an increased risk with a type of kidney disease, research involving academics at The University of Nottingham has discovered.

30 Jun 2016

Study: Zika virus infections last longer during pregnancy

University of Wisconsin-Madison researchers studying monkeys have shown that one infection with Zika virus protects against future infection, though pregnancy may drastically prolong the time the virus stays in the body.

29 Jun 2016

Mice studies reveal new insights into neurons that cause symptoms of Rett syndrome

Two studies in mice from Baylor College of Medicine, Texas, reveal new insights into neurons that mediate symptoms typical of the postnatal neurological disorder Rett syndrome.

29 Jun 2016

Study demonstrates epigenetic link between environment and pubertal onset in humans

Danish researchers have discovered a possible epigenetic link between the environment and pubertal timing.

28 Jun 2016

High levels of zinc may lead to kidney stone formation

David Killilea, PhD, a staff scientist at Children's Hospital Oakland Research Institute- the research arm of UCSF Benioff Children's Hospital Oakland - co-authored a study into the causes of kidney stones.

28 Jun 2016

Study offers array of new insights into nature of Plasmodium vivax

A team of scientists has uncovered the global, evolving, and historic make-up of Plasmodium vivax, one of the five species of malaria that infect humans.

28 Jun 2016

ISU researchers design nanomachine capable of detecting mock version of Ebola virus

Imagine you want to build an intricate work of architecture, like a castle. Now imagine that, once all its individual components are brought together, the castle builds itself automatically. Finally, imagine this castle is so small that it's measured on the same scale as DNA, viruses and small molecules.

28 Jun 2016

Scientists detect biological markers of chronic fatigue syndrome in gut bacteria

Physicians have been mystified by chronic fatigue syndrome, a condition where normal exertion leads to debilitating fatigue that isn't alleviated by rest. There are no known triggers, and diagnosis requires lengthy tests administered by an expert.

28 Jun 2016

Genomic techniques help scientists understand diversity of P.vivax parasites

While most malaria research has focused on the parasite Plasmodium falciparum, which is common in Africa, another parasite, Plasmodium vivax (P.vivax) is responsible for the majority of malaria infections outside this region, causing an estimated 15.8 million clinical malaria cases each year.

28 Jun 2016

Genetics News and Research

Latest Genetics News and Research

European Commission approves extended indication for Amgen's Kyprolis (carfilzomib) for the treatment of relapsed multiple myeloma patients

Researchers identify astroglia-mediated mechanism for causing FXS symptoms in mice

Scientists discover new genetic variations linked to increased myeloma risk

LouLou Foundation, ODC announce 11 new grants for research on CDKL5 deficiency

Scientists identify genetic mutations linked to synchronous colorectal cancers

Novel technique could help discover genes linked to complex traits in any animal model

Study shows how genetic variants control immune cell response to pathogens

Scientists develop light-activated injectable device to stimulate nerve cells

Risk of blindness from spinal-fusion surgery has declined, study shows

Women with BRCA1 gene mutation at increased risk of aggressive uterine cancer

Recommendations for integrating genomic results into clinical practice

Study links alpha-defensin genes to IgA nephropathy risk

Study: Zika virus infections last longer during pregnancy

Mice studies reveal new insights into neurons that cause symptoms of Rett syndrome

Study demonstrates epigenetic link between environment and pubertal onset in humans

High levels of zinc may lead to kidney stone formation

Study offers array of new insights into nature of Plasmodium vivax

ISU researchers design nanomachine capable of detecting mock version of Ebola virus

Scientists detect biological markers of chronic fatigue syndrome in gut bacteria

Genomic techniques help scientists understand diversity of P.vivax parasites

eBook: Using iPSCs models for human disease research and drug discovery eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting