Genetics News and Research

Latest Genetics News and Research

Epigenetic changes drive successful metastases of pancreatic cancer cells

A multicenter team of researchers reports that a full genomic analysis of tumor samples from a small number of people who died of pancreatic cancer suggests that chemical changes to DNA that do not affect the DNA sequence itself yet control how it operates confer survival advantages on subsets of pancreatic cancer cells.

17 Jan 2017

MGH researchers identify protein that may protect tumor-initiating cells in breast cancer

Massachusetts General Hospital investigators have identified a protein that may play an essential role in maintaining a population of tumor-initiating cells (TICs) -- treatment-resistant cells responsible for cancer recurrence and metastasis -- in breast cancer, as well as a compound that appears to reduce the molecule's ability to protect TICs from the effects of chemotherapy.

17 Jan 2017

Knowledge bank approach could help find best treatment option for AML patients

An international collaboration led by clinical researchers at the Wellcome Trust Sanger Institute has shown proof-of-concept that truly personalised therapy will be possible in the future for people with cancer.

17 Jan 2017

Researchers explore how metastatic pancreatic cancer gets ‘reprogrammed’ for optimal malignancy

Metastatic pancreatic cancer -- cancer that has spread from the pancreas to other tissues and is responsible for most patient deaths -- changes its metabolism and is "reprogrammed" for optimal malignancy, according to new findings reported Jan. 16 in Nature Genetics.

16 Jan 2017

Researchers discover underlying cause for formation of granulomas

Granulomas are tissue nodules of immune cells that occur in diseases such as tuberculosis and sarcoidosis and can damage many organs.

16 Jan 2017

Vaccine campaign targeting freshers could hold key to reducing spread of meningitis

A campaign targeted at students arriving at university for the first time could hold the key to reducing the spread of meningitis and septicaemia, say researchers at the universities of Nottingham and Leicester.

12 Jan 2017

Concussions accelerate Alzheimer's disease-related brain atrophy and cognitive decline, research finds

New research has found concussions accelerate Alzheimer's disease-related brain atrophy and cognitive decline in people who are at genetic risk for the condition.

12 Jan 2017

NovaSeq, the new sequencer by Illumina, said to transform the field of genomics

Illumina, Inc., the global leader in next-generation sequencing technology, today introduced the NovaSeqTM Series, a new and scalable sequencing architecture expected one day to enable a $100 genome. Unveiled at the J.P. Morgan Healthcare Conference, this platform redefines high throughput sequencing with unrivaled throughput, ease of use, low per sample costs, and unmatched flexibility.

From Illumina, Inc. 12 Jan 2017

Inhibition of EZH2 protein could be new strategy to treat multiple myeloma

In a study published in the scientific journal Oncotarget, researchers from Uppsala University show how the protein EZH2 affects the development of multiple myeloma, and that inhibition of EZH2 could be used as a new strategy to treat the disease.

12 Jan 2017

New Vanderbilt Center offers comprehensive care for patients with Marfan syndrome and aortic disease

With the recent opening of the Vanderbilt Marfan Syndrome and Aortic Disorders Center, the state's only comprehensive clinic serving entire families, hundreds of patients with connective tissue disorders now have a one-stop shop for health care.

12 Jan 2017

Epigenetic modification may be cause of adult throat cancers linked to alcohol, tobacco use

A team of researchers at the Research Institute of the McGill University Health Centre has found an epigenetic modification that might be the cause of 15% of adult cancers of the throat linked to alcohol and tobacco use.

12 Jan 2017

Genes implicated in rare pediatric epilepsy contribute to common forms of disorder, study finds

An international study led by Columbia University Medical Center and NewYork-Presbyterian researchers has found that several genes previously implicated only in rare, severe forms of pediatric epilepsy also contribute to common forms of the disorder.

12 Jan 2017

Forensic experts need statistical models to give weight to DNA-evidence

How do forensic scientists deal with complex DNA-evidence found at crime scenes? Giulia Cereda developed new statistical models to analyse them.

11 Jan 2017

CSHL scientists create first model of genetically induced obesity in fruit flies

Why do people become obese? Poor dietary choices and overeating seem like clear causes, but what is at the root of these behaviors? Significantly overweight people may be genetically predisposed to be affected disproportionately when faced with the ready availability of calorie-laden treats.

11 Jan 2017

Study shows how phage-resistant cells become susceptible upon co-incubation with sensitive bacteria

Bacteriophages (phages) are probably the most abundant entities in nature, often exceeding bacterial densities by an order of magnitude.

11 Jan 2017

Folic acid supplements can reduce risk of having pregnancy affected by neural tube defects

Despite the mandatory addition of folic acid to enriched grain products in the United States, many women still do not consume adequate amounts of this important vitamin, according to an editorial written by Laura E. Mitchell, Ph.D., professor in the Department of Epidemiology, Human Genetics and Environmental Sciences at The University of Texas Health Science Center at Houston School of Public Health.

11 Jan 2017

Roswell Park study provides new insights into gene mutations that can lead to cancer

Predisposition to cancer and cancer progression can result from gene mutations that cause elevated rates of genetic damage.

11 Jan 2017

Roswell Park researchers identify gene signatures that may help predict fatal prostate cancers

Standard therapy for prostate cancer, the third-leading cause of cancer-related deaths in American men, is based on blocking androgens, the male sex hormones.

11 Jan 2017

Scientists identify molecular pathway in the brain that may help find better treatments for dementia

Rutgers University scientists have discovered a molecular pathway in the brain that may help provide answers to long-term memory problems in the elderly and aid researchers in identifying drug-based therapies to prevent dementia.

11 Jan 2017

MGH researchers identify gene mutations linked to rare congenital condition involving lack of nose

Researchers from Massachusetts General Hospital led a large, international research team that has identified gene mutations associated with a rare congenital condition involving the absence of a nose and often accompanied by defects involving the eye and reproductive systems.

11 Jan 2017

Genetics News and Research

Latest Genetics News and Research

Epigenetic changes drive successful metastases of pancreatic cancer cells

MGH researchers identify protein that may protect tumor-initiating cells in breast cancer

Knowledge bank approach could help find best treatment option for AML patients

Researchers explore how metastatic pancreatic cancer gets ‘reprogrammed’ for optimal malignancy

Researchers discover underlying cause for formation of granulomas

Vaccine campaign targeting freshers could hold key to reducing spread of meningitis

Concussions accelerate Alzheimer's disease-related brain atrophy and cognitive decline, research finds

NovaSeq, the new sequencer by Illumina, said to transform the field of genomics

Inhibition of EZH2 protein could be new strategy to treat multiple myeloma

New Vanderbilt Center offers comprehensive care for patients with Marfan syndrome and aortic disease

Epigenetic modification may be cause of adult throat cancers linked to alcohol, tobacco use

Genes implicated in rare pediatric epilepsy contribute to common forms of disorder, study finds

Forensic experts need statistical models to give weight to DNA-evidence

CSHL scientists create first model of genetically induced obesity in fruit flies

Study shows how phage-resistant cells become susceptible upon co-incubation with sensitive bacteria

Folic acid supplements can reduce risk of having pregnancy affected by neural tube defects

Roswell Park study provides new insights into gene mutations that can lead to cancer

Roswell Park researchers identify gene signatures that may help predict fatal prostate cancers

Scientists identify molecular pathway in the brain that may help find better treatments for dementia

MGH researchers identify gene mutations linked to rare congenital condition involving lack of nose

eBook: Using iPSCs models for human disease research and drug discovery eBook

Latest eBooks

Industry Focus eBook - Neurology/Neuroscience - 2nd edition

Industry focus eBook: Genomics (4th edition)

Industry Focus eBook - Clinical & Point of Systems Diagnostics (1st edition)

Editorial Focus eBook - Peptides and Oligonucleotides (2nd edition)

How Programmable Nanobiology Could Drive the Fifth Industrial Revolution

Dr. Anthony Grice

Building quality into drug development for safer, faster medicines