Genetics News and Research

Latest Genetics News and Research

GRU combines with national Cooperative to improve treatment of reproductive health

Georgia Regents University has joined the national Cooperative Multicenter Reproductive Medicine Network designed to enable large clinical trials that improve the diagnosis and treatment of reproductive health issues such as male and female infertility.

2 Jan 2014

Integration of Parma Community General Hospital and EMH Healthcare into UH system receives approval

University Hospitals (UH) has received final approval from state and federal government regulators this week for the integration of Parma Community General Hospital and EMH Healthcare into the UH health system.

28 Dec 2013

Protein responsible for excretion of copper in body cells utilizes unique transport mechanism

We are fundamentally dependent on the presence of copper in the cells of the body. Copper is actually part of the body's energy conversion and protective mechanisms against oxygen radicals, as well as part of the immune system, and it also has great importance for the formation of e.g. hormones and neurotransmitters.

28 Dec 2013

Unprecedented, atom-scale simulation of G protein-coupled receptor site's transformation

Roughly 40 percent of all medications act on cells' G protein-coupled receptors (GPCRs). One of these receptors, beta 2 adrenergic receptor site (B2AR), naturally transforms between two base configurations; knowing the precise location of each of approximately 4,000 atoms is crucial for ensuring a snug fit between it and the drug.

28 Dec 2013

Researchers explore ways to overcome transplant rejection

Given that 10.5 % of patients who receive a transplant reject the new organ, researchers at the Center of Research and Advanced Studies of the National Polytechnic Institute (Cinvestav) are working in the design of a tool capable of preventing this problem.

27 Dec 2013

FNIH Biomarkers Consortium announces initial results of I-SPY 2 trial for breast cancer

The I-SPY 2 TRIAL, a randomized phase II clinical trial for breast cancer launched through a unique partnership with the Foundation for the National Institutes of Health (FNIH) Biomarkers Consortium and sponsored by QuantumLeap Healthcare Collaborative has graduated the first two drugs from its innovative, multidrug standing platform trial.

27 Dec 2013

EMA accepts Otsuka's marketing authorisation application for tolvaptan for treatment of ADPKD

Otsuka Pharmaceutical Co., Ltd. announced today that the European Medicines Agency (EMA) has accepted the submission of a marketing authorisation application (MAA) for the potential approval of tolvaptan for the treatment of autosomal dominant polycystic kidney disease (ADPKD).

27 Dec 2013

Genetics of rheumatoid arthritis contributes to biology and drug discovery

The results of the largest international study to date into the genetic basis of rheumatoid arthritis shed light on the biology of the disease and provide evidence that large-scale genetic studies can assist in the identification of new drugs for complex disorders such as rheumatoid arthritis.

26 Dec 2013

Researchers uncover new genetic clue that contributes to increased risk of type 2 diabetes

An international team of researchers in Mexico and the United States has uncovered a new genetic clue that contributes to an increased risk of developing type 2 diabetes, particularly the elevated risk among Mexican and other Latin American populations.

26 Dec 2013

Changes to LZTR1 gene predispose people to develop schwannomas

Changes to a gene called LZTR1 predispose people to develop a rare disorder where multiple tumors called schwannomas form near nerve pathways, according to a study published today in the journal Nature Genetics and led by researchers from the University of Alabama at Birmingham.

24 Dec 2013

Variation in oxytocin receptor gene influences face recognition skills, study finds

New findings suggest the oxytocin receptor, a gene known to influence mother-infant bonding and pair bonding in monogamous species, also plays a special role in the ability to remember faces. This research has important implications for disorders in which social information processing is disrupted, including autism spectrum disorder. In addition, the finding may lead to new strategies for improving social cognition in several psychiatric disorders.

24 Dec 2013

Surgeons at French hospital perform first Navio UKR procedures

Blue Belt Technologies announces the first Navio™ unicondylar knee replacement (UKR) procedures performed in France, completed on September 30th, October 15th and Nov 4th 2013 by Professor Philippe Neyret and Dr. Sébastien Lustig at Hospices Civils de Lyon in France.

23 Dec 2013

Six common diseases arise from DNA changes, finds new research

Many rare disorders are caused by gene mutation, like sickle cell anemia. Yet until now the underlying genetic cause of more common conditions - for example, rheumatoid arthritis - has evaded scientists for years.

22 Dec 2013

Neuroscience researchers discover gene that controls response to cocaine

UT Southwestern neuroscience researchers have identified a gene that controls the response to cocaine by comparing closely related strains of mice often used to study addiction and behavior patterns.

22 Dec 2013

Amgen reports that Phase 3 DESCARTES study for high cholesterol meets primary endpoint

Amgen today announced that the Phase 3 DESCARTES (Durable Effect of PCSK9 Antibody CompARed wiTh PlacEbo Study) study evaluating the long-term 52-week safety and efficacy of evolocumab for the treatment of high cholesterol met its primary endpoint of percent reduction from baseline in low-density lipoprotein cholesterol (LDL-C) at week 52.

20 Dec 2013

UC Irvine scientists find that reprogramming of liver 'clock' may contribute to metabolic disorders

A high-fat diet affects the molecular mechanism controlling the internal body clock that regulates metabolic functions in the liver, UC Irvine scientists have found. Disruption of these circadian rhythms may contribute to metabolic distress ailments, such as diabetes, obesity and high blood pressure.

20 Dec 2013

Researchers identify molecular link between liver cancer, obesity, alcoholism, and hepatitis

Obesity, alcoholism, and chronic hepatitis all increase the risk of getting liver cancer, which is the third leading cause of cancer death worldwide. Obesity in particular is driving a significant increase in liver cancer in the United States.

20 Dec 2013

Researchers map cell's complex genetic interactions to fix UV damaged DNA

Researchers at the University of California, San Diego School of Medicine, with colleagues in The Netherlands and United Kingdom, have produced the first map detailing the network of genetic interactions underlying the cellular response to ultraviolet (UV) radiation.

19 Dec 2013

Neurocognitive abnormalities ‘fundamental’ to schizophrenia

Rare copy-number variants that confer a high risk for schizophrenia or autism are associated with impaired cognition in carriers without psychiatric disorders, researchers report in Nature.

19 Dec 2013

Randomized control trials to study clinical effectiveness of high dose flu vaccine in nursing homes

One of the highest risk groups for developing pneumonia or even dying from the flu is the elderly, especially in group settings such as nursing homes.

19 Dec 2013

Genetics News and Research

Latest Genetics News and Research

GRU combines with national Cooperative to improve treatment of reproductive health

Integration of Parma Community General Hospital and EMH Healthcare into UH system receives approval

Protein responsible for excretion of copper in body cells utilizes unique transport mechanism

Unprecedented, atom-scale simulation of G protein-coupled receptor site's transformation

Researchers explore ways to overcome transplant rejection

FNIH Biomarkers Consortium announces initial results of I-SPY 2 trial for breast cancer

EMA accepts Otsuka's marketing authorisation application for tolvaptan for treatment of ADPKD

Genetics of rheumatoid arthritis contributes to biology and drug discovery

Researchers uncover new genetic clue that contributes to increased risk of type 2 diabetes

Changes to LZTR1 gene predispose people to develop schwannomas

Variation in oxytocin receptor gene influences face recognition skills, study finds

Surgeons at French hospital perform first Navio UKR procedures

Six common diseases arise from DNA changes, finds new research

Neuroscience researchers discover gene that controls response to cocaine

Amgen reports that Phase 3 DESCARTES study for high cholesterol meets primary endpoint

UC Irvine scientists find that reprogramming of liver 'clock' may contribute to metabolic disorders

Researchers identify molecular link between liver cancer, obesity, alcoholism, and hepatitis

Researchers map cell's complex genetic interactions to fix UV damaged DNA

Neurocognitive abnormalities ‘fundamental’ to schizophrenia

Randomized control trials to study clinical effectiveness of high dose flu vaccine in nursing homes

eBook: Using iPSCs models for human disease research and drug discovery eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting