Genetics News and Research

Latest Genetics News and Research

New theory regarding cause and development of endometriosis

Changes to two previously unstudied genes are the centerpiece of a new theory regarding the cause and development of endometriosis, a chronic and painful disease affecting 1 in 10 women.

10 Mar 2014

Edison Pharmaceuticals initiates Phase 2B/3 study of EPI-743 in children with Leigh syndrome

Edison Pharmaceuticals today announced the initiation of a phase 2B/3 study entitled, "A Phase 2B/3 Open-label Study of EPI-743 in Children with Leigh Syndrome" to be conducted in conjunction with Dainippon Sumitomo Pharma Co, Ltd.

10 Mar 2014

Mutations in gene associated with leukaemia may affect growth, intellectual development in children

Mutations in a gene associated with leukaemia cause a newly described condition that affects growth and intellectual development in children, new research reports.

10 Mar 2014

People with type 2 diabetes have epigenetic changes on DNA

People with type 2 diabetes have epigenetic changes on their DNA that healthy individuals do not have. This has been shown in a major study by researchers at Lund University. The researchers also found epigenetic changes in a large number of genes that contribute to reduced insulin production.

9 Mar 2014

STSI releases Scripps Wellderly Genome Resource to explore genetic cause for certain illness

Scientists exploring the genetic causes of illnesses such as Alzheimer's disease, heart disease, cancer and diabetes now have a new tool - a reference DNA dataset built by researchers at Scripps Translational Science Institute (STSI).

7 Mar 2014

BWH researchers explore newer approaches to treat Alzheimer's disease

A team of Alzheimer's disease (AD) researchers at Brigham and Women's Hospital (BWH) has been able to study the underlying causes of AD and develop assays to test newer approaches to treatment by using stem cells derived from related family members with a genetic predisposition to (AD).

7 Mar 2014

TAZ gene represents potential target for drug therapies to treat aggressive types of breast cancer

Significance: Understanding more about how the different types of cells in breast tissue develop improves our knowledge of breast cancer. TAZ represents a potential new target for drug therapies to treat aggressive types of breast cancer.

7 Mar 2014

Ohr Pharmaceutical partners with CSHL to develop trodusquemine and related analogs

Ohr Pharmaceutical, a pharmaceutical company focused on the development of novel therapeutics for large unmet medical needs, and leading global cancer research center Cold Spring Harbor Laboratory (CSHL) today announced the establishment of DepYmed Inc., a new joint venture to develop trodusquemine and related analogs.

6 Mar 2014

New findings shed light on how gene mutation causes motor neurone disease

Researchers have discovered a mechanism that may explain how a recently discovered mutation causes two devastating neurological diseases.

6 Mar 2014

New findings shed light on how gene mutation causes motor neurone disease

Researchers have discovered a mechanism that may explain how a recently discovered mutation causes two devastating neurological diseases.

6 Mar 2014

Safeguard Scientifics reports net income of $24 million for fourth quarter 2013

Safeguard Scientifics, Inc. today announced fourth quarter and full-year 2013 financial results. For the three months ended December 31, 2013, Safeguard's net income was $24.0 million, or $1.10 per share, compared to net loss of $10.8 million, or $0.51 per share for the same period in 2012. For the year ended December 31, 2013, Safeguard's net loss was $35.5 million, or $1.66 per share, compared to $39.4 million, or $1.88 per share for the same period in 2012.

6 Mar 2014

Scientists reveal how a genetic code variation results in devastating brain diseases

New findings reveal how a mutation, a change in the genetic code that causes neurodegeneration, alters the shape of DNA, making cells more vulnerable to stress and more likely to die.

6 Mar 2014

Novel cancer immunotherapy approach may provide new weapon against most deadly tumors

A novel approach to cancer immunotherapy - strategies designed to induce the immune system to attack cancer cells - may provide a new and cost-effective weapon against some of the most deadly tumors, including ovarian cancer and mesothelioma.

6 Mar 2014

Low-dose oral interferon may reduce risk of HCV relapse in patients with mild liver fibrosis

Chronic hepatitis C virus (HCV) infection can lead to serious diseases such as cirrhosis and cancer of the liver, so viral clearance and prevention of relapse are important treatment goals.

6 Mar 2014

Treating cystic fibrosis: an interview with Simon Bedson, Senior Vice President and International General Manager at Vertex

Cystic fibrosis is a rare, life-shortening genetic disease for which there is no cure. It affects more than 75,000 people worldwide. In CF, thick, sticky mucus blocks the passages in many organs, leading to a variety of symptoms. In particular, mucus builds up and clogs airways in the lungs making it easier for bacteria to grow.

5 Mar 2014

Local hyperthermia treatment induces mechanism of anti-tumor immune resistance

A combination of iron-oxide nanoparticles and an alternating magnetic field, which together generate heat, have activated an immune system response to tumors in mice according to an accepted manuscript by Dartmouth-Hitchcock Norris Cotton Center researchers in the journal Nanomedicine: Nanotechnology, Biology and Medicine released online on February 24, 2014.

5 Mar 2014

Chemotherapy induces long-lasting epigenetic changes in survivors' blood cells

Many breast cancer survivors experience fatigue and other debilitating symptoms that persist months to years after their course of treatment has ended.

5 Mar 2014

Studies identify gene signals involved with BMI and their connection to: heart disease, diabetes

Two recent genetic studies expand the list of genes involved with body fat and body mass index, and their connection to major Western health problems: heart disease, high blood pressure and diabetes.

5 Mar 2014

Two genetic studies expand list of genes connected to major Western health problems

Two recent genetic studies expand the list of genes involved with body fat and body mass index, and their connection to major Western health problems: heart disease, high blood pressure and diabetes. One study showed that higher body mass index (BMI) caused harmful effects on the risk of type 2 diabetes, high blood pressure and inflammation, while another study found gene signals linked to higher levels of body fat metrics, without showing causality.

5 Mar 2014

The Gordon & Llura Gund Foundations donates $3M to support Autism Speaks' Aut10K program

Autism Speaks, the world's leading autism science and advocacy organization, today announced that The Gordon & Llura Gund Foundation and The Gordon & Llura Gund 93 Foundation have donated a combined $3 million to support Autism Speaks' Autism Ten Thousand Genomes (Aut10K) program to sequence the world's largest collection of whole genomes of individuals with autism spectrum disorder (ASD) and their family members.

5 Mar 2014

Genetics News and Research

Latest Genetics News and Research

New theory regarding cause and development of endometriosis

Edison Pharmaceuticals initiates Phase 2B/3 study of EPI-743 in children with Leigh syndrome

Mutations in gene associated with leukaemia may affect growth, intellectual development in children

People with type 2 diabetes have epigenetic changes on DNA

STSI releases Scripps Wellderly Genome Resource to explore genetic cause for certain illness

BWH researchers explore newer approaches to treat Alzheimer's disease

TAZ gene represents potential target for drug therapies to treat aggressive types of breast cancer

Ohr Pharmaceutical partners with CSHL to develop trodusquemine and related analogs

New findings shed light on how gene mutation causes motor neurone disease

New findings shed light on how gene mutation causes motor neurone disease

Safeguard Scientifics reports net income of $24 million for fourth quarter 2013

Scientists reveal how a genetic code variation results in devastating brain diseases

Novel cancer immunotherapy approach may provide new weapon against most deadly tumors

Low-dose oral interferon may reduce risk of HCV relapse in patients with mild liver fibrosis

Treating cystic fibrosis: an interview with Simon Bedson, Senior Vice President and International General Manager at Vertex

Local hyperthermia treatment induces mechanism of anti-tumor immune resistance

Chemotherapy induces long-lasting epigenetic changes in survivors' blood cells

Studies identify gene signals involved with BMI and their connection to: heart disease, diabetes

Two genetic studies expand list of genes connected to major Western health problems

The Gordon & Llura Gund Foundations donates $3M to support Autism Speaks' Aut10K program

eBook: Using iPSCs models for human disease research and drug discovery eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research