Genetics News and Research

Latest Genetics News and Research

Research shows mutation in Prox1 gene may lead to memory, learning problems

St. Jude Children's Research Hospital investigators showed a gene named Prox1 is a key player in normal development of a brain structure crucial for learning and memory and remains active throughout life, nurturing the cells vital for making new memories.This study focused on a small region of the hippocampus known as the dentate gyrus, a brain structure needed for memory and learning that is home to the subgranular zone where the neural stem cells destined to become granule cells are housed. The dentate gyrus is one of two regions of the adult brain where neural stem cells continue to produce the precursor cells that ultimately differentiate into neurons.

18 Aug 2010

Study shows increase in IL-6 secretion can reduce Tarceva sensitivity to treat lung tumor cells

One of the most tantalizing developments in anti-cancer therapy over recent years has been the advent of targeted treatments, which have proven highly effective in holding aggressive cancers at bay in certain patients, although typically only for a limited period of time.

18 Aug 2010

Luminex donates new MAGPIX system to Papua New Guinea Institute of Medical Research

Luminex Corporation, the worldwide leader in multiplexed solutions, today announced it has donated the first commercial unit of its newly launched MAGPIX® instrument to Professor Peter Siba and his scientific team at the Papua New Guinea Institute of Medical Research. The instrument will be used onsite in Papua New Guinea to progress malaria research led by Dr. Peter Zimmerman, Professor of International Health, Genetics and Biology at the Center for Global Health and Diseases at Case Western Reserve University.

From Luminex 18 Aug 2010

Xenon Pharmaceuticals commences phase 2 clinical trial of XEN402 therapy for PHN

Xenon Pharmaceuticals Inc. announced today that it has initiated a phase 2 clinical trial evaluating its novel topical XEN402 therapy for the treatment of PHN.

17 Aug 2010

Study discovers multiple effects of SSRIs on cells

A new discovery about selective serotonin reuptake inhibitors (SSRIs) suggests that these drugs, which are used to treat mental health disorders like depression and anxiety, have multiple effects on our cells. In a research report published in the August 2010 issue of GENETICS, researchers used yeast cells to identify secondary drug targets or pathways affected by SSRIs. Such secondary pathways could help explain why different people taking the same drug may experience different effects, and could also lead to new types of drugs altogether.

17 Aug 2010

IBCERCC to improve existing research programs for breast cancer

A newly formed advisory committee will develop and coordinate a strategic federal research agenda on environmental and genetic factors related to breast cancer. The 19 member Interagency Breast Cancer and Environmental Research Coordinating Committee was established by the National Institute of Environmental Health Sciences, in collaboration with the National Cancer Institute, to review all breast cancer research efforts conducted or supported by federal agencies.

17 Aug 2010

Experimental drug benefits women with advanced ovarian or breast tumours caused by BRCA gene faults

An experimental drug called olaparib has been shown to shrink tumours in women whose advanced cancers were caused by faults in their BRCA genes.

17 Aug 2010

Albert Einstein College of Medicine named 1 of 5 Nathan Shock Centers

Albert Einstein College of Medicine of Yeshiva University has been named one of the National Institutes of Health's (NIH) Nathan Shock Centers of Excellence in the Basic Biology of Aging. The select group of five centers nationwide provides leadership in the pursuit of basic research into the biology of aging. Einstein's designation includes a $3.1 million, five-year grant from the NIH's National Institute on Aging.

17 Aug 2010

Non-viral gene therapy delays onset of eye disease

In one of only two studies of its kind, a study from researchers at Tufts University School of Medicine and the Sackler School of Graduate Biomedical Sciences at Tufts demonstrates that non-viral gene therapy can delay the onset of some forms of eye disease and preserve vision. The team developed nanoparticles to deliver therapeutic genes to the retina and found that treated mice temporarily retained more eyesight than controls.

17 Aug 2010

SIK2 impacts cell division cycle, regulates ovarian cancer response to chemotherapy: Research

For the first time, Salt Inducible Kinase 2 (SIK2) has been found to play a critical role in cell division and to regulate the response of some ovarian cancers to chemotherapy.Findings were reported by researchers from The University of Texas MD Anderson Cancer Center in the August issue of Cancer Cell. The study adds to growing evidence that combination therapies targeting different phases of the cell division cycle are vital for optimal cancer treatment.

17 Aug 2010

Parkinson’s disease linked to genetic alteration of immune system: Study

Parkinson’s disease (PD), a severely crippling disease of the nerves and brain has been linked to genes that affect the immune system according to new research. In these patients the immune system may go awry attacking healthy tissues or failing to fight infections that leave people susceptible to the condition scientists say.

16 Aug 2010

Interleukin Genetics transfers stock trading from NYSE Amex to OTCQB Marketplace

Interleukin Genetics, Inc. today announced that trading of shares of the Company's common stock will be transferred from the NYSE Amex to the OTCQB™ Marketplace effective today, August 16, 2010. Investors in the Company can trade the stock easily in this marketplace, where Interleukin Genetics' symbol will now be ILIU.

16 Aug 2010

Recent research on schizophrenia published in journal Current Directions in Psychological Science

It has been nearly a century since the term "schizophrenia" was first used to describe what was then considered a hopeless and incurable disorder of thought and emotion. Schizophrenia is still baffling to both scientists and the general public, but it is no longer considered hopeless. Significant advances have been made on several fronts in fathoming and combating this debilitating mental illness-from genetics to neuroscience to the psychosocial aspects of the disorder.

16 Aug 2010

Researchers pace embryonic heart with laser

Scientists at Case Western Reserve University and Vanderbilt University found that pulsed light can pace contractions in an avian embryonic heart, with no apparent damage to the tissue. The work, "Optical pacing of the embryonic heart," will be published in the advanced online issue of Nature Photonics on Aug. 15, 2010.According to the scientists, this non-invasive device may prove an effective tool in understanding how environmental factors that alter an embryo's heart rate lead to congenital defects. It may also lead to investigations of cardiac electrophysiology at the cellular, tissue and organ levels, and possibly the development of a new generation of pacemakers.

16 Aug 2010

Adverse effects in childhood lead to immune impairment later in life

The emotional pains we suffer in childhood can lead to weakened immune systems later in life, according to a new study.Based on this new research, the amount of this immune impairment even enhances that caused by the stress of caregiving later in life."What happens in childhood really matters when it comes to your immune response in the latter part of your life," explained Janice Kiecolt-Glaser, professor of psychology and psychiatry at Ohio State University. She explained her work at the annual meeting of the American Psychological Association in San Diego.

16 Aug 2010

Researchers discover genetic alterations responsible for Kabuki syndrome

Using a new, rapid and less expensive DNA sequencing strategy, scientists have discovered genetic alterations that account for most cases of Kabuki syndrome, a rare disorder that causes multiple birth defects and mental retardation. Instead of sequencing the entire human genome, the new approach sequences just the exome, the 1-2 percent of the human genome that contains protein-coding genes.

16 Aug 2010

Common genetic variation in HLA region associated with late-onset sporadic Parkinson's disease: Research

A team of researchers has discovered new evidence that Parkinson's disease may have an infectious or autoimmune origin. "Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease" appears online in Nature Genetics.

16 Aug 2010

Legal scholar calls for FDA to regulate all health-related genetic tests

An opinion piece by a legal scholar from the Johns Hopkins Berman Institute of Bioethics in this week's issue of Nature calls for the Food and Drug Administration to regulate all health-related genetic tests — whether available directly to consumers or through a health care provider — using an approach that imposes requirements proportionate to a test's level of risk.

13 Aug 2010

LabCorp announces collaboration between Esoterix Clinical Trials Services, Clearstone Central Laboratories

Laboratory Corporation of America Holdings announced today a collaboration between Esoterix Clinical Trials Services, a division of LabCorp, and Clearstone Central Laboratories, a global central laboratory specializing in drug development and pharmaceutical services.

13 Aug 2010

Interleukin Genetics second-quarter net loss from continuing operations decreases to $1.9 million

Interleukin Genetics, Inc. today announced financial and operational results for the second quarter ended June 30, 2010.

13 Aug 2010

Genetics News and Research

Latest Genetics News and Research

Research shows mutation in Prox1 gene may lead to memory, learning problems

Study shows increase in IL-6 secretion can reduce Tarceva sensitivity to treat lung tumor cells

Luminex donates new MAGPIX system to Papua New Guinea Institute of Medical Research

Xenon Pharmaceuticals commences phase 2 clinical trial of XEN402 therapy for PHN

Study discovers multiple effects of SSRIs on cells

IBCERCC to improve existing research programs for breast cancer

Experimental drug benefits women with advanced ovarian or breast tumours caused by BRCA gene faults

Albert Einstein College of Medicine named 1 of 5 Nathan Shock Centers

Non-viral gene therapy delays onset of eye disease

SIK2 impacts cell division cycle, regulates ovarian cancer response to chemotherapy: Research

Parkinson’s disease linked to genetic alteration of immune system: Study

Interleukin Genetics transfers stock trading from NYSE Amex to OTCQB Marketplace

Recent research on schizophrenia published in journal Current Directions in Psychological Science

Researchers pace embryonic heart with laser

Adverse effects in childhood lead to immune impairment later in life

Researchers discover genetic alterations responsible for Kabuki syndrome

Common genetic variation in HLA region associated with late-onset sporadic Parkinson's disease: Research

Legal scholar calls for FDA to regulate all health-related genetic tests

LabCorp announces collaboration between Esoterix Clinical Trials Services, Clearstone Central Laboratories

Interleukin Genetics second-quarter net loss from continuing operations decreases to $1.9 million

Sequencing & Genomics: Elevating Science and Healthcare eBook

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