Genetics News and Research

Latest Genetics News and Research

Vitiligo associated with genes variations linked to body's immune response

Scientists including researchers from the University of Florida have discovered additional evidence that generalized vitiligo - a disease that typically causes patches of white skin on the face, neck and extremities that pop star Michael Jackson may have experienced - is associated with slight variations in genes that play a role in the body's natural defenses.

8 Jun 2010

$Progenics presents Phase 1 PSMA ADC therapy study data for taxane-refractory prostate cancer at ASCO 2010$

Progenics presents Phase 1 PSMA ADC therapy study data for taxane-refractory prostate cancer at ASCO 2010

Progenics Pharmaceuticals, Inc. today presented the design and rationale of an ongoing phase 1 trial of its prostate-specific membrane antigen antibody drug conjugate (PSMA ADC) therapy at the 2010 Annual Meeting of the American Society of Clinical Oncology (ASCO). This phase 1 trial is assessing the safety, tolerability and initial clinical activity of progressively increasing doses of PSMA ADC in patients with progressive, metastatic, hormone-refractory prostate cancer following prior taxane chemotherapy.

8 Jun 2010

Genetic mutations help predict risk of prostate cancer in younger men: Researchers

Prostate cancer has become more common in younger men, and it's often more aggressive in these men. A new study from researchers at the University of Michigan Comprehensive Cancer Center has found that a series of genetic mutations could help detect this early onset prostate cancer.

8 Jun 2010

Lawsuit to be launched over breast cancer gene patent

BRCA1 and BRCA2 are two genes that have been identified to hold a key to women’s susceptibility to get breast or ovarian cancer. Changes also known as mutations in these genes are significant in women who go on to develop breast or ovarian cancer. Melbourne-based company Genetic Technologies Limited (GTL) has the exclusive license from American biotechnology company Myriad Genetics to carry out testing for the genes in Australia. Myriad holds a patent for these genes.

7 Jun 2010

Promising clinical data on CDX-011 in metastatic melanoma presented at ASCO Annual Meeting

Celldex Therapeutics, Inc. today announced the presentation of promising clinical data on CDX-011 in metastatic melanoma at the 46th Annual Meeting of the American Society of Clinical Oncology in Chicago, Illinois. The Phase 2 study has met its primary endpoint and the results support additional studies in this indication.

7 Jun 2010

Vitiligo is associated with variations in genes that play role in body's natural defenses: Scientists

Scientists including researchers from the University of Florida have discovered additional evidence that generalized vitiligo — a disease that typically causes patches of white skin on the face, neck and extremities that pop star Michael Jackson may have experienced — is associated with slight variations in genes that play a role in the body's natural defenses.

7 Jun 2010

Alcohol consumption, cigarette smoking associated with teen migraines, TTH : Study

A novel study by German researchers reported that alcohol consumption and cigarette smoking were associated with increased migraines and tension-type headaches in high school students. Coffee drinking and physical inactivity were associated specifically with migraines. Results of this study, the first to investigate modifiable risk factors for different types of headaches in a youth population, appear online early in Headache, a journal published by Wiley-Blackwell on behalf of the American Headache Society.

7 Jun 2010

NewLink Genetics reports positive data from Phase 2 trial of HyperAcute-Pancreas cancer immunotherapy

NewLink Genetics Corporation today announced positive Phase 2 clinical trial data of its HyperAcute®-Pancreas cancer immunotherapy combined with standard adjuvant chemotherapy in patients with surgically resectable pancreatic cancer. The study results suggest a potentially longer disease-free survival and one-year overall survival in this patient group than reported in previous studies of surgery and adjuvant therapy alone. These data were presented in a poster session at the American Society of Clinical Oncology (ASCO) annual meeting.

7 Jun 2010

Study identifies potential link between Gilbert's Syndrome, childhood acute lymphoblastic leukemia

Scientists from the Barbara Ann Karmanos Cancer Institute and Wayne State University School of Medicine, both in Detroit, and the Children's Hospital of Michigan/Detroit Medical Center, presented preliminary data that identified a potential link between Gilbert's Syndrome and the development of a specific subtype of childhood acute lymphoblastic leukemia (ALL). The findings were announced today at the 2010 American Society of Clinical Oncology Annual Meeting.

7 Jun 2010

Positive data on retreatment with brentuximab vedotin in Hodgkin lymphoma, ALCL presented at ASCO

Seattle Genetics, Inc. and Millennium: The Takeda Oncology Company, a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, today reported data on Hodgkin lymphoma and systemic anaplastic large cell lymphoma (ALCL) patients retreated with single-agent brentuximab vedotin (SGN-35). Preliminary data demonstrate that objective responses were achieved in seven out of 11 retreatment experiences and that brentuximab vedotin was well-tolerated in the retreatment setting.

7 Jun 2010

Celldex Therapeutics reports mature data from CDX-011 Phase 1/2 study in advanced breast cancer

Celldex Therapeutics, Inc. today announced that mature results from a Phase 1/2 study evaluating CDX-011 in advanced stage breast cancer patients were presented at the 46th Annual Meeting of the American Society of Clinical Oncology (ASCO). CDX-011 is an experimental antibody-drug conjugate (ADC) directed against glycoprotein NMB (GPNMB) and linked to a potent cancer cell-killing drug, monomethyl-auristatin E (MMAE).

7 Jun 2010

Alder Biopharmaceuticals reports positive data from ALD518 Phase 2a clinical trial for NSCLC

Alder Biopharmaceuticals Inc. today announced that patients with late-stage non-small cell lung cancer (NSCLC) showed improvement in cancer-related anemia and symptoms of the disease in a Phase 2a clinical trial of ALD518, a monoclonal antibody directed against interleukin-6 (IL-6).

7 Jun 2010

June Cold Spring Harbor Protocols features electrophoresis in RNA analysis and avian embryos

Gel electrophoresis is one of the most important and frequently used techniques in RNA analysis. Electrophoresis is used for RNA detection, quantification, purification by size and quality assessment. Gels are involved in a wide variety of methods including northern blotting, primer extension, footprinting and analyzing processing reactions. The two most common types of gels are polyacrylamide and agarose.

5 Jun 2010

$2M federal grant to double computing power at Southwest Foundation For Biomedical Research

The "computer ranch" at the Southwest Foundation for Biomedical Research (SFBR), one of the world's largest clusters of computers for human gene research, will more than double in size this summer, thanks to a $2 million federal grant that will speed the pace of discovery at the Foundation's AT&T Genomics Computing Center.

5 Jun 2010

6th Research Congress of the EAPC reflects research in palliative care

The global interest for research in palliative care is increasing rapidly and The 6th Research Congress of the EAPC reflects this with a record number of abstracts and attendees -- more than 660 abstracts from 39 different countries will be presented to over 1200 international researchers and clinicians.

4 Jun 2010

Life Technologies partners to create Genomic Cancer Care Alliance

Life Technologies Corporation today announced the creation of the Genomic Cancer Care Alliance to help people battling cancer gain access to treatment options found through analysis of their genomic information. Founding partners include Fox Chase Cancer Center, Scripps Genomic Medicine, and the Translational Genomics Research Institute (TGen). The announcement came during the Consumer Genetics Conference being held June 2-4 in Boston.

4 Jun 2010

A sense of humor keeps people healthy

A sense of humor helps to keep people healthy and increases their chances of reaching retirement age. But after the age of 70, the health benefits of humor decrease, researchers at the Norwegian University of Science and Technology (NTNU) have found.

4 Jun 2010

Researchers underscore role of jumping genes in maintaining genetic diversity

Using high-throughput sequencing to map the locations of a common type of jumping gene within a person's entire genome, researchers at the University of Pennsylvania School of Medicine found extensive variation in these locations among the individuals they studied, further underscoring the role of these errant genes in maintaining genetic diversity.

4 Jun 2010

GPI executive director announces keynote speakers, panel topics for 2010 World Stem Cell Summit

Bernard Siegel, executive director of the Genetics Policy Institute and co-chair of the 2010 World Stem Cell Summit, announced the selection of keynote speakers for the World Stem Cell Summit, which is taking place at the Detroit Marriott Renaissance Center in Detroit, Michigan, October 4-6.

4 Jun 2010

Researchers identify region of DNA that may contain gene linked to progression, spread of bowel cancer

Scientists have identified a region of DNA that appears to be involved in the development of pre-cancerous bowel growths (polyps) and that may contain a gene involved in the progression of bowel cancer.

4 Jun 2010

Genetics News and Research

Latest Genetics News and Research

Vitiligo associated with genes variations linked to body's immune response

Progenics presents Phase 1 PSMA ADC therapy study data for taxane-refractory prostate cancer at ASCO 2010

Genetic mutations help predict risk of prostate cancer in younger men: Researchers

Lawsuit to be launched over breast cancer gene patent

Promising clinical data on CDX-011 in metastatic melanoma presented at ASCO Annual Meeting

Vitiligo is associated with variations in genes that play role in body's natural defenses: Scientists

Alcohol consumption, cigarette smoking associated with teen migraines, TTH : Study

NewLink Genetics reports positive data from Phase 2 trial of HyperAcute-Pancreas cancer immunotherapy

Study identifies potential link between Gilbert's Syndrome, childhood acute lymphoblastic leukemia

Positive data on retreatment with brentuximab vedotin in Hodgkin lymphoma, ALCL presented at ASCO

Celldex Therapeutics reports mature data from CDX-011 Phase 1/2 study in advanced breast cancer

Alder Biopharmaceuticals reports positive data from ALD518 Phase 2a clinical trial for NSCLC

June Cold Spring Harbor Protocols features electrophoresis in RNA analysis and avian embryos

$2M federal grant to double computing power at Southwest Foundation For Biomedical Research

6th Research Congress of the EAPC reflects research in palliative care

Life Technologies partners to create Genomic Cancer Care Alliance

A sense of humor keeps people healthy

Researchers underscore role of jumping genes in maintaining genetic diversity

GPI executive director announces keynote speakers, panel topics for 2010 World Stem Cell Summit

Researchers identify region of DNA that may contain gene linked to progression, spread of bowel cancer

eBook: Using iPSCs models for human disease research and drug discovery eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging