Genetics News and Research

Latest Genetics News and Research

Multi-ancestry study reveals 187 new genetic risk factors for prostate cancer

In a comprehensive multi-ancestry GWAS meta-analysis, researchers identified 451 risk variants for prostate cancer, including 187 new variants, demonstrating the utility of such studies across diverse populations. This analysis not only increased understanding of genetic risk factors but also differentiated between aggressive and non-aggressive prostate cancer types, underscoring the potential of genetic risk scoring in guiding screening and early detection strategies.

12 Nov 2023

UCI researchers discover gene critical for muscle repair

University of California, Irvine researchers have identified a gene expressed during regeneration that is critical for muscle repair.

12 Nov 2023

Preclinical research points to a promising new treatment option for pancreatic cancer patients

Preclinical research published in the Journal for ImmunoTherapy of Cancer points to a promising new treatment option for people with pancreatic cancer.

10 Nov 2023

New research aims to decipher how animals discard half their genes

New research is underway to decipher a fascinating biological puzzle - how some animals can naturally discard more than half of their genetic information during embryonic development.

9 Nov 2023

Tumor-immune interactions predict treatment responses in multiple myeloma

A multicenter study led by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine shows how interactions between tumor cells and immune components of the microenvironment can impact treatment responses and outcomes in patients newly diagnosed with multiple myeloma who undergo combination treatments that include targeted immunotherapy.

9 Nov 2023

Study compiles the most comprehensive list of genetic variants associated with prostate cancer risk

A globe-spanning scientific team has compiled the most comprehensive list of genetic variants associated with prostate cancer risk - 451 in all - through a whole-genome analysis that ranks as the largest and most diverse investigation into prostate cancer genetics yet.

9 Nov 2023

Cannabis use alters DNA methylation, with implications beyond smoking effects

A large-scale meta-analysis in Molecular Psychiatry reveals that lifetime cannabis use is associated with DNA methylation changes in peripheral blood, which could have implications for understanding the long-term health effects of cannabis consumption.

8 Nov 2023

Study finds 4% of Icelanders to carry an actionable genotype associated with shortened lifespan

Scientists at deCODE genetics, a subsidiary of Amgen, have published a study on actionable genotypes detected in the Icelandic population and their association with lifespan.

8 Nov 2023

Gamma delta T cells engineered to be more potent and long-lasting against cancer

UCLA scientists have developed a new method to engineer more powerful immune cells that can potentially be used for "off-the-shelf" cell therapy to treat challenging cancers.

8 Nov 2023

Study sheds new light on the variety of cellular causes of rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease characterized by inflammation that leads to pain, joint damage, and disability, which affects approximately 18 million people worldwide.

8 Nov 2023

Scientists unravel the mystery of how cells keep glutathione levels in check

If a delivery person leaves a package on your front step without pinging you, you likely won't know it's there.

8 Nov 2023

Can adding RNA sequencing to germline genetic testing improve accuracy and clinical sensitivity over time compared to DNA sequencing alone?

Concurrent sequencing of DNA and RNA to detect the predisposition to hereditary cancer.

8 Nov 2023

Pharmacogenomics holds promise for personalized dementia therapies

Pharmacogenomics-based studies in the research for personalized therapeutics for dementia

8 Nov 2023

Targeting MYC-SPT5 interaction could lead to novel cancer therapies

MYC family genes are essential for the human organism. According to current knowledge, they regulate the expression of most cellular genes.

7 Nov 2023

Study provides insights into the epidemiology and genetics of clonal hematopoiesis

A comprehensive new study from deCODE genetics, a subsidiary of Amgen, published today in Nature Genetics, provides insights into the epidemiology and somatic and germline genetics of clonal hematopoiesis.

7 Nov 2023

To what extent can genetic variations explain the associations between screen time and psychiatric problems in children?

Researchers investigated the role of genetics in the phenotypic association between screen time and psychiatric problems using a large population-based cohort study of preadolescents.

7 Nov 2023

Study links gut bacteria single-nucleotide polymorphisms to BMI

Researchers investigated the potential implications of single-nucleotide variations in gut-residing bacterial species (microbiome) on human health.

7 Nov 2023

Virtual brain bank creates a powerful resource for research on epilepsy, brain tumors

A new virtual brain bank spanning five Chicago academic medical centers and led by University of Illinois Chicago will create a powerful new resource for clinical care and research on epilepsy, brain tumors and neurological disorders.

6 Nov 2023

Individuals with genetic predisposition for physical activity have fewer cardiovascular risk factors

In a study conducted at the University of Jyväskylä's Faculty of Sport and Health Sciences, it was found that individuals with a genetic predisposition for higher levels of physical activity have fewer risk factors for cardiovascular diseases and a reduced risk of developing hypertension, cerebrovascular diseases, and type 2 diabetes.

6 Nov 2023

Telomouse model provides a valuable resource for in-depth aging and cancer research

Researchers introduce the "Telomouse". By making a subtle genetic alteration in standard lab mice, they've made their telomeres, which protect the chromosome ends, more closely resemble those in humans.

6 Nov 2023

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Genetics News and Research

Latest Genetics News and Research

Multi-ancestry study reveals 187 new genetic risk factors for prostate cancer

UCI researchers discover gene critical for muscle repair

Preclinical research points to a promising new treatment option for pancreatic cancer patients

New research aims to decipher how animals discard half their genes

Tumor-immune interactions predict treatment responses in multiple myeloma

Study compiles the most comprehensive list of genetic variants associated with prostate cancer risk

Cannabis use alters DNA methylation, with implications beyond smoking effects

Study finds 4% of Icelanders to carry an actionable genotype associated with shortened lifespan

Gamma delta T cells engineered to be more potent and long-lasting against cancer

Study sheds new light on the variety of cellular causes of rheumatoid arthritis

Scientists unravel the mystery of how cells keep glutathione levels in check

Can adding RNA sequencing to germline genetic testing improve accuracy and clinical sensitivity over time compared to DNA sequencing alone?

Pharmacogenomics holds promise for personalized dementia therapies

Targeting MYC-SPT5 interaction could lead to novel cancer therapies

Study provides insights into the epidemiology and genetics of clonal hematopoiesis

To what extent can genetic variations explain the associations between screen time and psychiatric problems in children?

Study links gut bacteria single-nucleotide polymorphisms to BMI

Virtual brain bank creates a powerful resource for research on epilepsy, brain tumors

Individuals with genetic predisposition for physical activity have fewer cardiovascular risk factors

Telomouse model provides a valuable resource for in-depth aging and cancer research

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