Graft Versus Host Disease News and Research

Latest Graft Versus Host Disease News and Research

Study compares cord blood to bone marrow for transplants

Umbilical cord blood transplants may offer blood cancer patients better outcomes than bone marrow transplants, according to an analysis of outcome data performed at the Statistical Center, Center for Blood and Marrow Transplant Research (CIBMTR), Medical College of Wisconsin, Milwaukee.

14 Jun 2007

New technique allows partial-match cell transplants for children with most resistant leukemia

Clinicians at St. Jude Children's Research Hospital have successfully demonstrated an improved technique for blood stem cell transplantations in children that shows promise for those most likely to fail standard treatment for leukemia.

16 Oct 2006

Enrichment of regulatory CD4+CD25+ T cells by inhibition of phospholipase D signaling

A signaling molecule with an affinity for alcohol has yielded a rapid, inexpensive way to make large numbers of immune cells that work like beat cops keeping misguided cells from attacking the body.

8 Aug 2006

Researchers discover two-way communication and stimulation between blood stem cells and T cells

When a transplant patient suffers complications such as graft rejection or graft-versus-host disease, physicians attempt to stop the body's immune response by targeting a patient's T cells.

13 Jul 2006

SuperGen receives patent for composition and method for treating graft-versus-host disease

SuperGen has announced the issuance of U.S. Patent No. 7,037,900 B2 entitled, "Composition and Method for Treating Graft-versus-Host Disease."

5 Jun 2006

Novel therapy for chronic graft-versus-host disease

A study by Dana-Farber Cancer Institute researchers offers the strongest evidence yet of the effectiveness of a novel therapy for chronic graft-versus-host disease (GVHD), a potentially life-threatening complication of donor bone marrow and stem cell transplants.

28 Mar 2006

Novel therapy for chronic graft-versus-host disease (GVHD) using Rituximab

Dana-Farber researchers found that rituximab reduced the severity of chronic graft-versus-host disease (GVHD) in 70 percent of the study participants.

27 Mar 2006

Scientists fight leukaemia with 'natural killer' cells

Scientists at the University of the West of England and the Bone Marrow Transplant Unit at the Bristol Children's Hospital have just won funding for a two-year project aimed at improving the outcome of bone marrow stem-cell transplants in young leukaemia patients.

8 Mar 2006

Mayo Clinic provides new strategy for designing better treatments for juvenile dermatomyositis

Mayo Clinic researchers, working with colleagues at the University of Minnesota and University of Pittsburgh, are the first to describe a new role for a specialized cell of the immune system in children suffering from a rare muscle-damaging disease known as juvenile dermatomyositis (JDM).

14 Nov 2005

Discovery could help make cellular immunotherapy safer

Researchers at the University of Michigan's Comprehensive Cancer Center have discovered the secret weapon behind the most powerful form of cancer immunotherapy known to medicine.

16 Oct 2005

Possible new therapy for lymphoma and leukemia patients

Marty Holmes, a landscaper from Stockton, Calif., had never heard of a regulatory T cell before his doctor suggested that it could be the key to helping him survive his cancer.

28 Sep 2005

Study addresses critical GVHD complication - limitations of bone marrow transplants

Together with 16 other institutions in the United States, University of Minnesota researchers led the largest study to date in patients with leukemia and related disorders undergoing bone marrow transplantation from unrelated donors.

2 Aug 2005

Maxim Pharmaceuticals issued patent for method of identifying therapeutically effective immunosupressive agents

Maxim Pharmaceuticals have announced the United States Patent and Trademark Office issued U.S. patent number 6,828,091 B2, entitled "Method of Identifying Immunosuppressive Agents."

23 Apr 2005

Cell replacement therapy offers a novel and powerful medical technology

Cell replacement therapy offers a novel and powerful medical technology. A type of embryonic stem cell, called a neural crest stem cell, that persists into adulthood in hair follicles was recently discovered by Maya Sieber-Blum, Ph.D., of the Medical College of Wisconsin, Milos Grim, MD Ph.D., of Charles University Prague, and their collaborators.

13 Dec 2004

New advances in sickle cell disease

Excruciating pain episodes, recurrent pneumonias, strokes, severe infections, chronic hemolytic anemia, and secondary pulmonary hypertension are common complications of sickle cell disease, a life-threatening inherited defect in blood that causes normally disc-shaped red blood cells to take on a sickle shape.

6 Dec 2004

Impaired cognitive and motor function following stem cell transplantation for severe blood disorders can improve

Patients who suffer a loss of cognitive and motor function as a result of stem cell transplantation for severe blood disorders are likely to see those functions return to previous levels after one year, according to a new study in the November 15, 2004, issue of Blood, the official journal of the American Society of Hematology.

8 Nov 2004

Peripheral blood transplants from donors may be more harmful than bone marrow transplants in pediatric leukemia patients

A new study has shown for the first time that transplantation of peripheral blood stem cells (PBSC) from sibling donors may be more harmful than bone marrow in pediatric leukemia patients.

3 Nov 2004

Scientists have developed a new technology capable of improving survival outcomes after bone marrow transplantation

The study was published in the September issue of the prestigious medical journal, British Journal of Hematology. The technology involves the rational design and application of tyrosine kinase inhibitors for the treatment of leukemia, lymphoma, and graft versus host disease.

8 Oct 2004

Bone marrow and stem cell transplantation rejection averted by UV light exposure

One of the unfortunate side effects of bone marrow and stem cell transplantation is that the newly implanted cells often stage an internal attack against the patient they're intended to help.

10 May 2004

Drug duo prevents life-threatening condition in children undergoing stem cell transplant

A drug duo appears to be a safe and effective way to prevent a serious condition called graft-versus-host-disease (GVHD) in youngsters undergoing a stem cell transplant

14 Apr 2004

Graft Versus Host Disease News and Research

Latest Graft Versus Host Disease News and Research

Study compares cord blood to bone marrow for transplants

New technique allows partial-match cell transplants for children with most resistant leukemia

Enrichment of regulatory CD4+CD25+ T cells by inhibition of phospholipase D signaling

Researchers discover two-way communication and stimulation between blood stem cells and T cells

SuperGen receives patent for composition and method for treating graft-versus-host disease

Novel therapy for chronic graft-versus-host disease

Novel therapy for chronic graft-versus-host disease (GVHD) using Rituximab

Scientists fight leukaemia with 'natural killer' cells

Mayo Clinic provides new strategy for designing better treatments for juvenile dermatomyositis

Discovery could help make cellular immunotherapy safer

Possible new therapy for lymphoma and leukemia patients

Study addresses critical GVHD complication - limitations of bone marrow transplants

Maxim Pharmaceuticals issued patent for method of identifying therapeutically effective immunosupressive agents

Cell replacement therapy offers a novel and powerful medical technology

New advances in sickle cell disease

Impaired cognitive and motor function following stem cell transplantation for severe blood disorders can improve

Peripheral blood transplants from donors may be more harmful than bone marrow transplants in pediatric leukemia patients

Scientists have developed a new technology capable of improving survival outcomes after bone marrow transplantation

Bone marrow and stem cell transplantation rejection averted by UV light exposure

Drug duo prevents life-threatening condition in children undergoing stem cell transplant

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Graft Versus Host Disease News and Research

Latest Graft Versus Host Disease News and Research

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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