Graft Versus Host Disease News and Research

Latest Graft Versus Host Disease News and Research

Partially-matched bone marrow transplants can eliminate sickle cell disease in some patients

In a preliminary clinical trial, investigators at Johns Hopkins have shown that even partially-matched bone marrow transplants can eliminate sickle cell disease in some patients, ridding them of painful and debilitating symptoms, and the need for a lifetime of pain medications and blood transfusions.

21 Sep 2012

Study sheds new light on why most bone marrow transplant patients suffer acute GVHD

A team of scientists led by a bone marrow transplant researcher at Fred Hutchinson Cancer Research Center has shed new light on why most bone marrow transplant patients who receive tissue-matched cells from unrelated donors still suffer acute graft-versus-host disease (GVHD).

6 Sep 2012

NCI awards Soligenix $300,000 SBIR grant for orBec Phase 2 chronic GI GVHD trial

Soligenix, Inc., a development stage biopharmaceutical company, announced today that the National Cancer Institute has awarded Soligenix a Small Business Innovation Research grant to support the conduct of a Phase 2 clinical trial designed to evaluate orBec (oral beclomethasone 17,21-dipropionate or BDP) as a treatment for the gastrointestinal manifestation of chronic Graft-versus-Host disease.

5 Sep 2012

Maraviroc reduces incidence of GvHD in blood cancer patients after bone marrow transplantation

An HIV drug that redirects immune cell traffic significantly reduces the incidence of a dangerous complication that often follows bone marrow transplants for blood cancer patients, according to research from the Perelman School of Medicine at the University of Pennsylvania that will be published today in the New England Journal of Medicine.

12 Jul 2012

Velos releases new iPad app for clinicians in oncology, bone marrow transplantation

Velos, Inc. today announced the release of Velos Aversi, an iPad app for clinicians in oncology and bone marrow transplantation. The app is now available for download on the Apple App Store.

1 Jun 2012

Soligenix first quarter revenues decrease to $647,418

Soligenix, Inc., a development stage biopharmaceutical company, announced today its financial results for the quarter ending March 31, 2012.

14 May 2012

Osiris Therapeutics first quarter total revenues decrease to $4.6M

Osiris Therapeutics, Inc., the leading stem cell company focused on developing and commercializing products to treat medical conditions in inflammatory, cardiovascular, orthopedic, and wound healing markets, announced today its results for the first quarter ended March 31, 2012.

11 May 2012

New combination therapy offers potential lifetime cure for advanced type 1 diabetes

City of Hope researchers developed a combination therapy to treat late-stage type 1 diabetes that appears to offer a potential lifetime cure for the disease without toxic side effects. The laboratory study is published in the May 9 edition of Science Translational Medicine.

11 May 2012

SEBM announces winners of 2012 Best Paper Awards

SEBM is pleased to announce the winners of the Best Paper Awards for articles published in the journal Experimental Biology and Medicine during 2011. SEBM recognizes the best paper annually in each of 3 categories: Clinical/Preclinical and Translation Research, Experimental Biology, and Interdisciplinary Research.

21 Apr 2012

UTHealth researcher studies novel cell therapy to prevent GVHD

A researcher at The University of Texas Health Science Center at Houston (UTHealth) is studying a novel cell therapy that could help avoid autoimmune problems after stem cell transplantation, as well as potentially treat other autoimmune diseases.

17 Apr 2012

Platelet activating factor plays a crucial role in development of graft-versus-host disease

A new discovery in mice may lead to new treatments that could make bone marrow transplants more likely to succeed and to be significantly less dangerous.

2 Apr 2012

Relief for dry eyes through scleral contact lenses

Susan Loughman is among the tens of millions of Americans who suffer dry eyes. She has an especially bad condition, which makes it feel like there's sandpaper in her eyes.

23 Mar 2012

CUMC scientists develop a way to recreate personalized immune mouse

Columbia University Medical Center (CUMC) scientists have developed a way to recreate an individual's immune system in a mouse. The "personalized immune mouse" offers researchers an unprecedented tool for individualized analysis of abnormalities that contribute to type 1 diabetes and other autoimmune diseases, starting at the onset of disease.

15 Mar 2012

Researchers identify molecule that helps decrease acute GVHD severity

Researchers have identified a molecule that helps control the severity of graft-versus-host disease, a life-threatening complication for many leukemia patients who receive a bone-marrow transplant.

12 Mar 2012

Some bone marrow cells could prevent rejection of transplanted kidney in recipients: Study

Researchers transplanted certain cells from the kidney donor’s bone marrow along with the new organ. Five of eight transplant recipients who tried the method so far were off immune-suppressing medication up to 2½ years later, the researchers reported Wednesday. The preliminary results were considered important enough to be published in the journal Science Translational Medicine even though the study still is under way, because the technique worked for patients who didn’t have well-matched or related donors.

8 Mar 2012

Bellicum raises $20M in Series B financing

Bellicum Pharmaceuticals, Inc. today announced that it has raised $20 million in a Series B financing. The funding will be used to advance its lead CaspaCIDe and DeCIDe programs through Phase 2 clinical development.

8 Mar 2012

Osiris provides update on status of development, commercialization agreement with Genzyme

Osiris Therapeutics, Inc., today provided an update on the status of the development and commercialization agreement with Genzyme, a Sanofi company.

10 Feb 2012

Researchers present results from 31 major studies of blood-related cancers at ASH 2011 meeting

Researchers from the John Theurer Cancer Center at Hackensack University Medical Center, one of the nation's top 50 best hospitals for cancer, presented results from 31 major studies of blood-related cancers - leukemia, lymphoma and multiple myeloma -- during the American Society of Hematology (ASH) Annual Meeting, December 10-13, 2011 in San Diego.

23 Dec 2011

Maraviroc reduces incidence of GvHD in blood cancer patients after ASCT

An HIV drug that redirects immune cell traffic appears to significantly reduce the dangerous complication graft-versus-host disease (GvHD) in blood cancer patients following allogeneic stem cell transplantation (ASCT), according to new research from the Perelman School of Medicine at the University of Pennsylvania that will be presented today at the 53rd American Society of Hematology Annual Meeting.

14 Dec 2011

Promising results from Fate Therapeutics' ProHema Phase 1b trial on hematologic malignancies

Fate Therapeutics, Inc. announced today promising clinical results from a Phase 1b trial of ProHema (FT1050-enhanced umbilical cord blood) as part of double-umbilical cord blood (UCB) transplants in adult patients with hematologic malignancies who have undergone reduced-intensity conditioning therapy.

14 Dec 2011

Graft Versus Host Disease News and Research

Latest Graft Versus Host Disease News and Research

Partially-matched bone marrow transplants can eliminate sickle cell disease in some patients

Study sheds new light on why most bone marrow transplant patients suffer acute GVHD

NCI awards Soligenix $300,000 SBIR grant for orBec Phase 2 chronic GI GVHD trial

Maraviroc reduces incidence of GvHD in blood cancer patients after bone marrow transplantation

Velos releases new iPad app for clinicians in oncology, bone marrow transplantation

Soligenix first quarter revenues decrease to $647,418

Osiris Therapeutics first quarter total revenues decrease to $4.6M

New combination therapy offers potential lifetime cure for advanced type 1 diabetes

SEBM announces winners of 2012 Best Paper Awards

UTHealth researcher studies novel cell therapy to prevent GVHD

Platelet activating factor plays a crucial role in development of graft-versus-host disease

Relief for dry eyes through scleral contact lenses

CUMC scientists develop a way to recreate personalized immune mouse

Researchers identify molecule that helps decrease acute GVHD severity

Some bone marrow cells could prevent rejection of transplanted kidney in recipients: Study

Bellicum raises $20M in Series B financing

Osiris provides update on status of development, commercialization agreement with Genzyme

Researchers present results from 31 major studies of blood-related cancers at ASH 2011 meeting

Maraviroc reduces incidence of GvHD in blood cancer patients after ASCT

Promising results from Fate Therapeutics' ProHema Phase 1b trial on hematologic malignancies

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

Graft Versus Host Disease News and Research

Latest Graft Versus Host Disease News and Research

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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